APHG - Fraser,E.; McDonagh,A.M.; Head,M.; Bishop,M.T.; Ironside,J.W.; Mann,D.M.A. - Neuronal and astrocytic responses involving the serotonergic system in human spongiform encephalopathies - Neuropathology and Applied Neurobiology 2003 Oct; 29(5): 482-95
ABRI - Brion,J.P.; Fraser,H.; Flament-Durand,J.; Dickinson,A.G. - Amyloid scrapie plaques in mice, and Alzheimer senile plaques, share common antigens with tau, a microtubule-associated protein - Neuroscience Letters 1987 Jul 9; 78(1): 113-8
ABTP - Brown,K.L.; Stewart,K.; Ritchie,D.; Fraser,H.; Morrison,W.I.; Bruce,M.E. - Follicular dendritic cells in scrapie pathogenesis - Archives of Virology. Supplementum 2000(16): 13-21
ABTQ - Brown,K.L.; Stewart,K.; Ritchie,D.L.; Mabbott,N.A.; Williams,A.; Fraser,H.; Morrison,W.I.; Bruce,M.E. - Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells - Nature Medicine 1999 Nov; 5(11): 1308-12
ABTR - Brown,K.L.; Stewart,K.; Bruce,M.E.; Fraser,H. - Severely combined immunodeficient (SCID) mice resist infection with bovine spongiform encephalopathy - Journal of General Virology 1997 Oct; 78(10): 2707-10
ABTS - Brown,K.L.; Stewart,K.; Bruce,M.E.; Fraser,H. - Scrapie in immunodeficient mice - Biochemical Society Transactions 1997 May; 25(2): 173S
ABXE - Bruce,M.E.; Boyle,A.; Cousens,S.N.; McConnell,I.; Foster,J.; Goldmann,W.; Fraser,H. - Strain characterization of natural sheep scrapie and comparison with BSE - Journal of General Virology 2002 Mar; 83(3): 695-704
ABXI - Bruce,M.E.; Will,R.G.; Ironside,J.W.; McConnell,I.; Drummond,D.; Suttie,A.; McCardle,L.; Chree,A.; Hope,J.; Birkett,C.R.; Cousens,S.N.; Fraser,H.; Bostock,C.J. - Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent - Nature 1997 Oct 2; 389(6650): 498-501
ABXD - Bruce,M.E.; Chree,A.; McConnell,I.; Foster,J.; Pearson,G.; Fraser,H. - Transmission of bovine spongiform encephalopathy and scrapie to mice: strain variation and the species barrier. - Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 1994 Mar 29; 343(1306): 405-11
AUQE - Bruce,M.E.; Chree,A.; Mconnell,I.; Foster,J.; Pearson,G.; Fraser,H. - Agent strain variation in BSE and scrapie - Transmissible Spongiform Encephalopathies. A Consultation on BSE with the Scientific Veterinary Committee of the Commission of the European Communities held in Brussels, September 14-15, 1993. Edited by R. Bradley and B. Marchant. European Commission, Agriculture, Document VI/4131/94-EN 1994, pp. 189-204
ABXL - Bruce,M.E.; McConnell,I.; Fraser,H.; Dickinson,A.G. - The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis. - Journal of General Virology 1991 Mar; 72(3): 595-603
ABXM - Bruce,M.E.; Fraser,H. - Scrapie strain variation and its implications - Current Topics in Microbiology and Immunology 1991; 172: 125-38
ABXS - Bruce,M.E.; Fraser,H. - Effects of age on cerebral amyloid plaques in murine scrapie - Neuropathology and Applied Neurobiology 1982 Jan-Feb; 8(1): 71-4
ABXT - Bruce,M.E.; Fraser,H. - Focal and asymmetrical vacuolar lesions in the brains of mice infected with certain strains of scrapie - Acta Neuropathologica 1982; 58(2): 133-40
ABXV - Bruce,M.E.; Fraser,H. - Effect of route of infection on the frequency and distribution of cerebral amyloid plaques in scrapie mice - Neuropathology and Applied Neurobiology 1981 Jul-Aug; 7(4): 289-98
ACZD - Curtis,R.; Fraser,H.; Foster,J.D.; Scott,J.R. - The correlation of electroretinographic and histopathological findings in the eyes of mice infected with the 79A strain of scrapie - Neuropathology and Applied Neurobiology 1989 Jan-Feb; 15(1): 75-89
ADIN - Dickinson,A.G.; Fraser,H.; McConnell,I.; Outram,G.W. - Mitogenic stimulation of the host enhances susceptibility to scrapie - Nature 1978 Mar 2; 272(5648): 54-5
ADIP - Dickinson,A.G.; Fraser,H.; Outram,G.W. - Scrapie incubation time can exceed natural lifespan - Nature 1975 Aug 28; 256(5520): 732-3
ADIK - Dickinson,A.G.; Fraser,H.; McConnell,I.; Outram,G.W.; Sales,D.I.; Taylor,D.M. - Extraneural competition between different scrapie agents leading to loss of infectivity - Nature 1975 Feb 13; 253(5492): 556
ADIS - Dickinson,A.G.; Taylor,D.M.; Fraser,H. - Depression of polymorph counts by various scrapie agents - Nature 1974 Apr 5; 248(448): 510-1
ADIV - Dickinson,A.G.; Fraser,H. - Scrapie: effect of Dh gene on incubation period of extraneurally injected agent. - Heredity 1972 Aug; 29(1): 91-3
ADIW - Dickinson,A.G.; Fraser,H.; Meikle,V.M.; Outram,G.W. - Competition between different scrapie agents in mice - Nature New Biology 1972 Jun 21; 237(77): 244-5
ADIY - Dickinson,A.G.; Fraser,H. - Genetical control of the concentration of ME7 scrapie agent in mouse spleen - Journal of Comparative Pathology 1969 Jul; 79(3): 363-6
ADIZ - Dickinson,A.G.; Fraser,H. - Modification of the pathogenesis of scrapie in mice by treatment of the agent - Nature 1969 May 31; 222(196): 892-3
ADJC - Dickinson,A.G.; Meikle,V.M.; Fraser,H. - Genetical control of the concentration of ME7 scrapie agent in the brain of mice - Journal of Comparative Pathology 1969 Jan; 79(1): 15-22
ADJE - Dickinson,A.G.; Meikle,V.M.; Fraser,H. - Identification of a gene which controls the incubation period of some strains of scrapie agent in mice - Journal of Comparative Pathology 1968 Jul; 78(3): 293-9
ADSS - Eikelenboom,P.; Rozemuller,J.M.; Kraal,G.; Stam,F.C.; McBride,P.A.; Bruce,M.E.; Fraser,H. - Cerebral amyloid plaques in Alzheimer's disease but not in scrapie-affected mice are closely associated with a local inflammatory process - Virchows Archiv. B, Cell Pathology Including Molecular Pathology 1991; 60(5): 329-36
ADST - Eikelenboom,P.; Scott,J.R.; McBride,P.A.; Rozemuller,J.M.; Bruce,M.E.; Fraser,H. - No evidence for involvement of plasma proteins or blood-borne cells in amyloid plaque formation in scrapie-affected mice. An immunohistoperoxidase study. - Virchows Archiv. B, Cell Pathology Including Molecular Pathology 1987; 53(4): 251-6
AECR - Foster,J.D.; McKelvey,W.; Fraser,H.; Chong,A.; Ross,A.; Parnham,D.; Goldmann,W.; Hunter,N. - Experimentally induced bovine spongiform encephalopathy did not transmit via goat embryos - Journal of General Virology 1999 Feb; 80(2): 517-24
AECX - Foster,J.D.; Hunter,N.; Williams,A.; Mylne,M.J.A.; McKelvey,W.A.C.; Hope,J.; Fraser,H.; Bostock,C.J. - Observations on the transmission of scrapie in experiments using embryo transfer - The Veterinary Record 1996 Jun 8; 138(23): 559-62
AECY - Foster,J.D.; Bruce,M.; McConnell,I.; Chree,A.; Fraser,H. - Detection of BSE infectivity in brain and spleen of experimentally infected sheep - The Veterinary Record 1996 Jun 1; 138(22): 546-8
AECZ - Foster,J.D.; Hope,J.; McConnell,I.; Bruce,M.; Fraser,H. - Transmission of bovine spongiform encephalopathy to sheep, goats, and mice - Slow Infections of the Central Nervous System (Ed. Bjornsson,J.; Carp,R.I.; Love,A.; Wisniewski,H.M.) 1994 Jun 6; 724 : 300-3
AUVQ - Foster,J.D.; McKelvey,W.A.C.; Mylne,M.J.A.; Williams,A.; Hunter,N.; Hope,J.; Fraser,H. - Studies on vertical transmission of scrapie in sheep and BSE in goats using embryo transfer - Transmissible Spongiform Encephalopathies. A Consultation on BSE with the Scientific Veterinary Committee of the Commission of the European Communities held in Brussels, September 14-15, 1993. Edited by R. Bradley and B. Marchant. European Commission, Agriculture, Document VI/4131/94-EN 1994, pp. 229-237
AEDA - Foster,J.D.; Hope,J.; Fraser,H. - Transmission of bovine spongiform encephalopathy to sheep and goats - The Veterinary Record 1993 Oct 2; 133(14): 339-41
AEDB - Foster,J.D.; McKelvey,W.A.C.; Mylne,M.J.A.; Williams,A.; Hunter,N.; Hope,J.; Fraser,H. - Studies on maternal transmission of scrapie in sheep by embryo transfer - The Veterinary Record 1992 Apr 18; 130(16): 341-3
AEDD - Foster,J.D.; Scott,J.R.; Fraser,H. - The use of monosodium glutamate in identifying neuronal populations in mice infected with scrapie - Neuropathology and Applied Neurobiology 1990 Oct; 16(5): 423-30
AEDH - Foster,J.D.; Davies,D.J.; Fraser,H. - Primary retinopathy in scrapie in mice deprived of light - Neuroscience Letters 1986 Dec 3; 72(1): 111-4
AEDI - Foster,J.D.; Fraser,H.; Bruce,M.E. - Retinopathy in mice with experimental scrapie - Neuropathology and Applied Neurobiology 1986 Mar-Apr; 12(2): 185-96
APXR - Fraser,H. - Continuing anxiety about BSE - The Veterinary Record 2004 Jan 10; 154(2): 62
ANMI - Fraser,H. - Origin of BSE - The Veterinary Record 2002 Nov 16; 151(20): 616
AEEE - Fraser,H. - Phillips report and the origin of BSE - The Veterinary Record 2000 Dec 16; 147(25): 724
AEEF - Fraser,H. - BSE and hindsight - The Veterinary Record 1998 Feb 28; 142(9): 227
AEEG - Fraser,H.; Brown,K.L.; Stewart,K.; McConnell,I.; McBride,P.A.; Williams,A. - Replication of scrapie in spleens of SCID mice follows reconstitution with wild-type mouse bone marrow - Journal of General Virology 1996 Aug; 77(8): 1935-40
AEEH - Fraser,H.; Behan,W.; Chree,A.; Crossland,G.; Behan,P. - Mouse inoculation studies reveal no transmissible agent in amyotrophic lateral sclerosis - Brain Pathology 1996 Apr; 6(2): 89-99
ANCG - Fraser,H.; Foster,J.D. - Transmission to mice, sheep and goats and bioassay of bovine tissues - Transmissible Spongiform Encephalopathies. A Consultation on BSE with the Scientific Veterinary Committee of the Commission of the European Communities held in Brussels, September 14-15, 1993. Edited by R. Bradley and B. Marchant. European Commission, Agriculture, Document VI/4131/94-EN 1994, pp. 145-159
AEEI - Fraser,H.; Pearson,G.R.; McConnell,I.; Bruce,M.E.; Wyatt,J.M.; Gruffydd-Jones,T.J. - Transmission of feline spongiform encephalopathy to mice - The Veterinary Record 1994 Apr 23; 134(17): 449
AEEJ - Fraser,H. - Diversity in the neuropathology of scrapie-like diseases in animals - British Medical Bulletin 1993 Oct; 49(4): 792-809
AEEK - Fraser,H.; Bruce,M.E.; Chree,A.; McConnell,I.; Wells,G.A.H. - Transmission of bovine spongiform encephalopathy and scrapie to mice - Journal of General Virology 1992 Aug; 73(8): 1891-7
APZJ - Fraser,H.; Bruce,M.E.; McConnell,I. - Murine scrapie strains, BSE models and genetics - Sub-Acute Spongiform Encephalopathies, edited by Ray Bradley, Marc Savey and Brian Marchant - Proceedings of a Seminar in the CEC Agricultural Research Programme, held in Brussels, 12-14 November 1990, 1991; 55: 131-47
AEEL - Fraser,H.; Bruce,M.E.; McBride,P.A.; Scott,J.R. - The molecular pathology of scrapie and the biological basis of lesion targeting - Progress in Clinical and Biological Research 1989; 317: 637-44
AEEM - Fraser,H.; Farquhar,C.F.; McConnell,I.; Davies,D. - The scrapie disease process is unaffected by ionising radiation - Progress in Clinical and Biological Research 1989; 317: 653-8
ANIC - Fraser,H.; McConnell,I.; Wells,G.A.H.; Dawson,M. - Transmission of bovine spongiform encephalopathy to mice - The Veterinary Record 1988 Oct 29; 123(18): 472
AEEN - Fraser,H.; Farquhar,C.F. - Ionising radiation has no influence on scrapie incubation period in mice - Veterinary Microbiology 1987 Mar; 13(3): 211-23
AEEO - Fraser,H. - Brain tumours in mice, with particular reference to astrocytoma - Food and Chemical Toxicology 1986 Feb; 24(2): 105-11
AEEP - Fraser,H.; Dickinson,A.G. - Targeting of scrapie lesions and spread of agent via the retino-tectal projection - Brain Research 1985 Oct 28; 346(1): 32-41
AEEQ - Fraser,H.; Bruce,M.E. - Experimental control of cerebral amyloid in scrapie in mice - Progress in Brain Research 1983; 59: 281-90
AEER - Fraser,H. - Neuronal spread of scrapie agent and targeting of lesions within the retino-tectal pathway - Nature 1982 Jan 14; 295(5845): 149-50
AEES - Fraser,H.; Dickinson,A.G. - Studies of the lymphoreticular system in the pathogenesis of scrapie: the role of spleen and thymus. - Journal of Comparative Pathology 1978 Oct; 88(4): 563-73
AEET - Fraser,H.; Hancock,P.M. - An investigation of the macrophage electrophoretic mobility test in the diagnosis of scrapie in sheep - Journal of Comparative Pathology 1977 Apr; 87(2): 267-74
AEEU - Fraser,H. - The pathology of a natural and experimental scrapie - Frontiers of Biology 1976; 44: 267-305
AEEV - Fraser,H.; Bruce,M. - Argyrophilic plaques in mice inoculated with scrapie from particular sources - Lancet 1973 Mar 17; 1(7803): 617-8
AEEW - Fraser,H.; Dickinson,A.G. - Scrapie in mice. Agent-strain differences in the distribution and intensity of grey matter vacuolation. - Journal of Comparative Pathology 1973 Jan; 83(1): 29-40
AEEX - Fraser,H.; Dickinson,A.G. - Pathogenesis of scrapie in the mouse: the role of the spleen. - Nature 1970 May 2; 226(244): 462-3
AEEY - Fraser,H. - The occurrence of nerve fiber degeneration in brains of mice inoculated with scrapie - Research in Veterinary Science 1969 Jul; 10(4): 338-41
AEEZ - Fraser,H. - Bilateral thalamic calcification in ageing mice - Journal of Pathology and Bacteriology 1968 Jul; 96(1): 220-2
AEFA - Fraser,H.; Dickinson,A.G. - The sequential development of the brain lesion of scrapie in three strains of mice - Journal of Comparative Pathology 1968 Jul; 78(3): 301-11
AEFB - Fraser,H.; Dickinson,A.G. - Distribution of experimentally induced scrapie lesions in the brain - Nature 1967 Dec 3; 216(122): 1310-1
AEFG - Fraser,J.R.; Foster,J.D.; Fraser,H. - Creutzfeldt-Jakob disease and bovine spongiform encephalopathy. Scrapie can be transmitted to mice by instillation of inoculum into the conjunctiva. - British Medical Journal 1996 Jan 20; 312(7024): 181
AEOF - Gibson,P.H.; Somerville,R.A.; Fraser,H.; Foster,J.D.; Kimberlin,R.H. - Scrapie associated fibrils in the diagnosis of scrapie in sheep - The Veterinary Record 1987 Feb 7; 120(6): 125-7
AFZU - Jeffrey,M.J.; Scott,J.R.; Williams,A.; Fraser,H. - Ultrastructural features of spongiform encephalopathy transmitted to mice from three species of bovidae - Acta Neuropathologica 1992; 84(5): 559-69
AFZV - Jeffrey,M.J.; Scott,J.R.; Fraser,H. - Scrapie inoculation of mice: light and electron microscopy of the superior colliculi. - Acta Neuropathologica 1991; 81(5): 562-71
AGJV - Kimberlin,R.H.; Walker,C.A.; Fraser,H. - The genomic identity of different strains of mouse scrapie is expressed in hamsters and preserved on reisolation in mice - Journal of General Virology 1989 Aug; 70(8): 2017-25
AHOK - Lucassen,P.J.; Williams,A.; Chung,W.C.J.; Fraser,H. - Detection of apoptosis in murine scrapie - Neuroscience Letters 1995 Oct 6; 198(3): 185-8
AIDS - McBride,P.A.; Eikelenboom,P.; Kraal,G.; Fraser,H.; Bruce,M.E. - PrP protein is associated with follicular dendritic cells of spleens and lymph nodes in uninfected and scrapie-infected mice - Journal of Pathology 1992 Dec; 168(4): 413-8
AIDT - McBride,P.A.; Bruce,M.E.; Fraser,H. - Immunostaining of scrapie cerebral amyloid plaques with antisera raised to scrapie-associated fibrils (SAF) - Neuropathology and Applied Neurobiology 1988 Jul-Aug; 14(4): 325-36
AIEA - McDermott,J.R.; Fraser,H.; Dickinson,A.G. - Reduced choline-acetyltransferase activity in scrapie mouse brain - Lancet 1978 Aug 5; 2(8084): 318-9
AJCO - Outram,G.W.; Dickinson,A.G.; Fraser,H. - Slow encephalopathies, inflammatory responses and arachis oil - Lancet 1975 Jan 25; 1(7900): 198-200
AJCP - Outram,G.W.; Dickinson,A.G.; Fraser,H. - Reduced susceptibility to scrapie in mice after steroid administration - Nature 1974 Jun 28; 249(460): 855-6
AJCQ - Outram,G.W.; Dickinson,A.G.; Fraser,H. - Developmental maturation of susceptibility to scrapie in mice - Nature 1973 Feb 23; 241(5391): 536-7
AJCR - Outram,G.W.; Fraser,H.; Wilson,D.T. - Scrapie in mice. Some effects on the brain lesion profile of ME7 agent due to genotype of donor, route of injection and genotype of recipient. - Journal of Comparative Pathology 1973 Jan; 83(1): 19-28
AKPX - Scott,J.R.; Foster,J.D.; Fraser,H. - Conjunctival instillation of scrapie in mice can produce disease - Veterinary Microbiology 1993 Apr; 34(4): 305-9
AKPY - Scott,J.R.; Davies,D.; Fraser,H. - Scrapie in the central nervous system: neuroanatomical spread of infection and Sinc control of pathogenesis. - Journal of General Virology 1992 Jul; 73(7): 1637-44
AKQA - Scott,J.R.; Fraser,H. - Enucleation after intraocular scrapie injection delays the spread of infection - Brain Research 1989 Dec 18; 504(2): 301-5
AKQB - Scott,J.R.; Fraser,H. - Transport and targeting of scrapie infectivity and pathology in the optic nerve projections following intraocular infection - Progress in Clinical and Biological Research 1989; 317: 645-52
AKQC - Scott,J.R.; Fraser,H. - Degenerative hippocampal pathology in mice infected with scrapie - Acta Neuropathologica 1984; 65(1): 62-8
ALNG - Taylor,D.M.; McConnell,I.; Fraser,H. - Scrapie infection can be established readily through skin scarification in immunocompetent but not immunodeficient mice - Journal of General Virology 1996 Jul; 77(7): 1595-9
ALNP - Taylor,D.M.; Fraser,H.; McConnell,I.; Brown,D.A.; Brown,K.L.; Lamza,K.A.; Smith,G.R. - Decontamination studies with the agents of bovine spongiform encephalopathy and scrapie - Archives of Virology 1994; 139(3-4): 313-26
ALON - Taylor,D.M.; Dickinson,A.G.; Fraser,H.; Marsh,R.F. - Evidence that transmissible mink encephalopathy agent is biologically inactive in mice - Neuropathology and Applied Neurobiology 1986 Mar-Apr; 12(2): 207-15
ALOP - Taylor,D.M.; Dickinson,A.G.; Fraser,H.; Robertson,P.A.; Salacinski,P.R.; Lowry,P.J. - Preparation of growth hormone free from contamination with unconventional slow viruses - Lancet 1985 Aug 3; 2(8449): 260-2
AMOW - Williams,A.; van Dam,A.M.; Ritchie,D.; Eikelenboom,P.; Fraser,H. - Immunocytochemical appearance of cytokines, prostaglandin E2 and lipocortin-1 in the CNS during the incubation period of murine scrapie correlates with progressive PrP accumulations - Brain Research 1997 Apr 18; 754(1-2): 171-80
AMOZ - Williams,A.E.; van Dam,A.M.; Man-A-Hing,W.K.H.; Berkenbosch,F.; Eikelenboom,P.; Fraser,H. - Cytokines, prostaglandins and lipocortin-1 are present in the brains of scrapie-infected mice - Brain Research 1994 Aug 22; 654(2): 200-6
AMPA - Williams,A.E.; Lawson,L.J.; Perry,V.H.; Fraser,H. - Characterization of the microglial response in murine scrapie - Neuropathology and Applied Neurobiology 1994 Feb; 20(1): 47-55
AMRG - Wisniewski,H.M.; Bruce,M.E.; Fraser,H. - Infectious etiology of neuritic (senile) plaques in mice - Science 1975 Dec 12; 190(4219): 1108-10
AMTC - Wrathall,A.E.; Brown,K.F.D.; Sayers,A.R.; Wells,G.A.H.; Simmons,M.M.; Farrelly,S.S.J.; Bellerby,P.J.; Squirrell,J.; Spencer,Y.I.; Wells,M.; Stack,M.J.; Bastiman,B.; Pullar,D.; Scatcherd,J.; Heasman,L.; Parker,J.; Hannam,D.A.; Helliwell,D.W.; Chree,A.; Fraser,H. - Studies of embryo transfer from cattle clinically affected by bovine spongiform encephalopathy (BSE) - The Veterinary Record 2002 Mar 23; 150(12): 365-78
AVOI - Wrathall,A.E.; Brown,K.F.D.; Fraser,H.; Chree,A.; Ferguson,C.A. - Embryos and uterine flush fluids from cattle with bovine spongiform encephalopathy are not infective for mice - Theriogenology 1997 Jan 1; 47(1): 384
AECS - Foster,J.D.; Farquhar,C.F.; Fraser,J.R; Somerville,R.A. - Immunolocalization of the prion protein in scrapie affected rodent retinas - Neuroscience Letters 1999 Jan 22; 260(1): 1-4
AXIV - Barr,J.; Ironside,J.W.; Watson,M.; Harris,N.; Fraser,J.R.; Barron,R. - A Proteomics Approach to Establishing New Surrogate Markers for the Diagnosis of TSE Disease - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.165
AWBP - Barr,J.B.; Watson,M.; Harris,N.; Brown,D.A.; Head,M.; Ironside,J.; Fraser,J.R.; Barron,R.M. - SELDI-assisted identification of biomarkers for TSE diagnosis - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions DIA-06
AQGR - Barr,J.B.; Somerville,R.A.; Chung,Y.L.; Fraser,J.R. - Microdissection: a method developed to investigate mechanisms involved in transmissible spongiform encephalopathy pathogenesis. - BMC Infectious Diseases 2004 Mar 3; 4(1): 8
ABCF - Baxter,H.C.; Fraser,J.R.; Liu,W.G.; Forster,J.L.; Clokie,S.; Steinacker,P.; Otto,M.; Bahn,E.; Wiltfang,J.; Aitken,A. - Specific 14-3-3 isoform detection and immunolocalization in prion diseases - Biochemical Society Transactions 2002 Aug; 30(4): 387-91
ABCG - Baxter,H.C.; Liu,W.G.; Forster,J.L.; Aitken,A.; Fraser,J.R. - Immunolocalisation of 14-3-3 isoforms in normal and scrapie-infected murine brain - Neuroscience 2002; 109(1): 5-14
ABEO - Belichenko,P.V.; Brown,D.A.; Jeffrey,M.J.; Fraser,J.R. - Dendritic and synaptic alterations of hippocampal pyramidal neurones in scrapie-infected mice - Neuropathology and Applied Neurobiology 2000 Apr; 26(2): 143-9
ABJQ - Black,C.J.; Johnston,A.R.; Fraser,J.R.; MacLeod,N. - Electrophysiological properties of dorsal lateral geniculate neurons in brain slices from ME7 scrapie-infected mice - Experimental Neurology 1998 Jan; 149(1): 253-61
AXJV - Brown,D.A.; Ironside,J.W.; Fraser,J.R.; Tuzi,N.L. - Cytoskeletal Disruption and the Role of The MAP Kinase Pathways in Two Neuronal Loss Models of Murine Scrapie - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.173
ANXD - Brown,D.A.; Bruce,M.E.; Fraser,J.R. - Comparison of the neuropathological characteristics of bovine spongiform encephalopathy (BSE) and variant Creutzfeldt-Jakob disease (vCJD) in mice - Neuropathology and Applied Neurobiology 2003 Jun; 29(3): 262-72
ABRX - Brown,D.A.; Belichenko,P.V.; Sales,J.; Jeffrey,M.J.; Fraser,J.R. - Early loss of dendritic spines in murine scrapie revealed by confocal analysis - Neuroreport 2001 Jan 22; 12(1): 179-83
ABTN - Brown,K.L.; Brown,J.; Ritchie,D.L.; Sales,J.; Fraser,J.R. - Fetal cell grafts provide long-term protection against scrapie induced neuronal loss - Neuroreport 2001 Jan 22; 12(1): 77-82
APGH - Chung,Y.L.; Barr,J.B.; Bhakoo,K.; Williams,S.C.R.; Bell,J.D.; Fraser,J.R. - N-acetyl aspartate estimation: a potential method for determining neuronal loss in the transmissible spongiform encephalopathies. - Neuropathology and Applied Neurobiology 2003 Oct; 29(5): 445-50
ACVO - Connolly,J.G.; Tate,R.J.; McLennan,N.F.; Brown,D.A.; Telling,G.C.; Fraser,J.R.; Head,M.W. - Properties of the cellular prion protein expressed in Xenopus oocytes - Neuroreport 2002 Jul 2; 13(9): 1229-33
ANWH - Fraser,J.R. - Recent progress in Transmissible Spongiform Encephalopathies - Neuropathology and Applied Neurobiology 2003; 29: 207-8
AEFD - Fraser,J.R. - What is the basis of transmissible spongiform encephalopathy induced neurodegeneration and can it be repaired? - Neuropathology and Applied Neurobiology 2002 Feb; 28(1): 1-11
AEFE - Fraser,J.R.; Brown,J.M.; Bruce,M.E.; Jeffrey,M.J. - Scrapie-induced neuron loss is reduced by treatment with basic fibroblast growth factor - Neuroreport 1997 Jul 7; 8(9-10): 2405-9
AEFF - Fraser,J.R. - Infectivity in extraneural tissues following intraocular scrapie infection - Journal of General Virology 1996 Oct; 77(10): 2663-8
APZI - Fraser,J.R. - Infectifity in extraneural tissues following intraocular scrapie infection - Journal of General Virology 1996 Aug; 77(8): 2663-8
AEFG - Fraser,J.R.; Foster,J.D.; Fraser,H. - Creutzfeldt-Jakob disease and bovine spongiform encephalopathy. Scrapie can be transmitted to mice by instillation of inoculum into the conjunctiva. - British Medical Journal 1996 Jan 20; 312(7024): 181
AEFC - Fraser,J.R.; Jeffrey,M.J.; Halliday,W.G.; Fowler,N.; Goodsir,C.M.; Brown,D.A. - Early loss of neurons and axon terminals in scrapie-affected mice revealed by morphometry and immunocytochemistry - Molecular and Chemical Neuropathology 1995 Feb-Apr; 24(2-3): 245-9
AEWF - Gregoire,N.; Fraser,J.R.; Pellissier,J.F.; Nicoli,J. - Synthetic growth hormone has no inducting effect in the development of a prion disease: an experimental study on the scrapie model in hamsters. - Journal of the Neurological Sciences 1997 Nov 25; 152(2): 224-5
ANES - Head,M.W.; Farquhar,C.F.; Mabbott,N.A.; Fraser,J.R. - The transmissible spongiform encephalopathies: pathogenic mechanisms and strategies for therapeutic intervention. - Expert Opinion on Therapeutic Targets 2001 Oct; 5(5): 569-585
AFYE - Jamieson,E.; Jeffrey,M.J.; Ironside,J.W.; Fraser,J.R. - Activation of Fas and caspase 3 precedes PrP accumulation in 87V scrapie - Neuroreport 2001 Nov 16; 12(16): 3567-72
AFYF - Jamieson,E.; Jeffrey,M.J.; Ironside,J.W.; Fraser,J.R. - Apoptosis and dendritic dysfunction precede prion protein accumulation in 87V scrapie - Neuroreport 2001 Jul 20; 12(10): 2147-53
AFZA - Jeffrey,M.J.; Martin,S.; Barr,J.B.; Chong,A.; Fraser,J.R. - Onset of accumulation of PrPres in murine ME7 scrapie in relation to pathological and PrP immunohistochemical changes - Journal of Comparative Pathology 2001 Jan; 124(1): 20-8
AFZC - Jeffrey,M.J.; Fraser,J.R. - Tubulovesicular particles occur early in the incubation period of murine scrapie - Acta Neuropathologica 2000 May; 99(5): 525-8
AFZE - Jeffrey,M.J.; Halliday,W.G.; Bell,J.; Johnston,A.R.; MacLeod,N.K.; Ingham,C.; Sayers,A.R.; Brown,D.A.; Fraser,J.R. - Synapse loss associated with abnormal PrP precedes neuronal degeneration in the scrapie-infected murine hippocampus - Neuropathology and Applied Neurobiology 2000 Feb; 26(1): 41-54
AFZF - Jeffrey,M.J.; Goodsir,C.M.; Holliman,A.; Higgins,R.J.; Bruce,M.E.; McBride,P.A.; Fraser,J.R. - Determination of the frequency and distribution of vascular and parenchymal amyloid with polyclonal and N-terminal-specific PrP antibodies in scrapie-affected sheep and mice - The Veterinary Record 1998 May 16; 142(20): 534-7
AFZG - Jeffrey,M.J.; Goodsir,C.M.; Bruce,M.E.; McBride,P.A.; Fraser,J.R. - In vivo toxicity of prion protein in murine scrapie: ultrastructural and immunogold studies. - Neuropathology and Applied Neurobiology 1997 Apr; 23(2): 93-101
AFZJ - Jeffrey,M.J.; Fraser,J.R.; Halliday,W.G.; Fowler,N.; Goodsir,C.M.; Brown,D.A. - Early unsuspected neuron and axon terminal loss in scrapie-infected mice revealed by morphometry and immunocytochemistry - Neuropathology and Applied Neurobiology 1995 Feb; 21(1): 41-9
AGBT - Johnston,A.R.; Fraser,J.R.; Jeffrey,M.J.; MacLeod,N. - Synaptic plasticity in the CA1 area of the hippocampus of scrapie-infected mice - Neurobiology of Disease 1998 Sep; 5(3): 188-95
AGBU - Johnston,A.R.; Fraser,J.R.; Jeffrey,M.J.; MacLeod,N. - Alterations in potassium currents may trigger neurodegeneration in murine scrapie - Experimental Neurology 1998 Jun; 151(2): 326-33
AGBV - Johnston,A.R.; Black,C.J.; Fraser,J.R.; MacLeod,N. - Scrapie infection alters the membrane and synaptic properties of mouse hippocampal CA1 pyramidal neurones - The Journal of Physiology 1997 Apr 1; 500(1): 1-15
ASGP - Johnston,A.R.; Black,C.J.; Fraser,J.R.; Manson,J.C.; Hope,J.; Clarke,A.R.; MacLeod,N. - Membrane-properties and synaptic plasticity in mouse ca1 hippocampal-neurons infected with me-7 scrapie or lacking the prion protein, studied in-vitro - Journal of Physiology 1996 Sep; 495: 15
ASGQ - Johnston,A.R.; Black,C.J.; Fraser,J.R.; MacLeod,N. - Physiological and morphological properties of scrapie- infected ca1 hippocampal pyramidal cells in the mouse - Journal of Physiology 1995 Nov; 489: 19-20
AOGR - Liu,W.G.; Brown,D.A.; Fraser,J.R. - Immunohistochemical comparison of anti-prion protein (PrP) antibodies in the CNS of mice infected with scrapie - Journal of Histochemistry and Cytochemistry 2003 Aug; 51(8): 1065-71
ASHT - Stewart,B.; Ironside,J.W.; Fraser,J.R. - Quantification or scrapie pathology following infection by the intramuscular, intraperitoneal and oral routes - Brain Pathology 1997; 7(4): 1380
ALMS - Taylor,D.M.; Fraser,J.R. - The potential risk of transmitting vCJD through surgery - The Journal of Hospital Infection 2000 Apr; 44(4): 318-9
AEFH - Fraser,K.B. - Systems of virus survival - Journal of Clinical Pathology. Supplement (Royal College of Pathologists) 1972; 6: 152-3
AIAG - Mastrangelo,P.; Serpell,L.; Dafforn,T.; Lesk,A.; Fraser,P.; Westaway,D. - A cluster of familial Creutzfeldt-Jakob disease mutations recapitulate conserved residues in Doppel: a case of molecular mimicry? - FEBS Letters 2002 Dec 4; 532(1-2): 21-6
ABTB - Brown,D.R.; Qin,K.; Herms,J.W.; Madlung,A.; Manson,J.; Strome,R.; Fraser,P.E.; Kruck,T.; von Bohlen,A.; Schulz-Schaeffer,W.J.; Giese,A.; Westaway,D.; Kretzschmar,H.A. - The cellular prion protein binds copper in vivo - Nature 1997 Dec 18-25; 390(6661): 684-7
ACVJ - Come,J.H.; Fraser,P.E.; Lansbury,P.T.Jr. - A kinetic model for amyloid formation in the prion diseases: importance of seeding. - Proceedings of the National Academy of Sciences of the United States of America 1993 Jul 1; 90(13): 5959-63
AROZ - Drisaldi,B.; Coomaraswamy,J.; Mastrangelo,P.; Strome,B.; Yang,J.; Watts,J.C.; Chishti,M.A.; Marvi,M.; Windl,O.; Ahrens,R.; Major,F.; Sy,M.S.; Kretzschmar,H.A.; Fraser,P.E.; Mount,H.T.J.; Westaway,D. - Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPc offset pro-apoptotic activity of the Doppel helix B/B' region. - The Journal of Biological Chemistry 2004 Dec 31; 279(53): 55443-54
ANSH - Qin,K.; Coomaraswamy,J.; Mastrangelo,P.; Yang,Y.; Lugowski,S.; Petromilli,C.; Prusiner,S.B.; Fraser,P.E.; Goldberg,J.M.; Chakrabartty,A.; Westaway,D. - The PrP-like protein Doppel binds copper - The Journal of Biological Chemistry 2003 Mar 14; 278(11): 8888-96
AJTU - Qin,K.; Yang,D.S.; Yang,Y.; Chishti,M.A.; Meng,L.J.; Kretzschmar,H.A.; Yip,C.M.; Fraser,P.E.; Westaway,D. - Copper(II)-induced conformational changes and protease resistance in recombinant and cellular PrP. Effect of protein age and deamidation. - The Journal of Biological Chemistry 2000 Jun 23; 275(25): 19121-31
ARVW - Silverman,G.L.; Yao,H.; Strome,R.; Laplanche,J.L.; Foncin,J.F.; George-Hyslop,P.St; Fraser,P.E.; Westaway,D. - Proteins which interact with wild-type and mutant N-terminal domains of human PrPc - Journal of Neuropathology and Experimental Neurology 1997; 56(N5): 596 Nr. 99
ANKD - Sunde,M.; Serpell,L.C.; Bartlam,M.; Fraser,P.E.; Pepys,M.B.; Blake,C.C. - Common core structure of amyloid fibrils by synchrotron X-ray diffraction - Journal of Molecular Biology 1997 Oct 31; 273(3): 729-39
AXYM - Watts,J.C.; Ng,V.; Horne,P.; Schmitt-Ulms,G.; Fraser,P.E.; Westaway,D. - Biochemical Properties of Wild Type Shadoo Protein from Mice - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.119
AWQF - Watts,J.C.; Drisaldi,B.; Yang,J.; Strome,B.; Horne,P.; Fraser,P.E.; Mount,H.T.J.; Schmitt-Ulms,G. - The novel CNS protein shadoo and PrPc share functional homology - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Oral sessions ORAL-35
AUQW - Watts,J.C.; Drisaldi,B.; Yang,J.; Strome,B.; Horne,P.; Fraser,P.E.; Mount,H.T.J.; Schmitt-Ulms,G.; Westaway,D. - Functional Analysis of Mammalian Prion Proteins: Shadoo and PrPc have overlapping activities - TSE-Forum, 6. Kongress - Nationale TSE-Forschungsplattform, Greifswald 26.6.-28.6.2006, Vortrag V-15
AXYP - Westaway,D.; Watts,J.C.; Ng,V.; Daude,N.; Yang,J.; Horne,P.; Strome,B.; Young,R.; Carlson,G.A.; Fraser,P.E.; Schmitt-Ulms,G. - Biological Activities of the Shadoo Protein - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.185
ANAU - Zou,W.Q.; Yang,D.S.; Fraser,P.E.; Cashman,N.R.; Chakrabartty,A. - All or none fibrillogenesis of a prion peptide - European Journal of Biochemistry 2001 Sep; 268(18): 4885-91