AYAB - Atarashi,R.; Moore,R.A.; Sim,V.L.; Hughson,A.G.; Dorward,D.W.; Onwubiko,H.A.; Priola,S.A.; Caughey,B. - Ultrasensitive detection of scrapie prion protein using seeded conversion of recombinant prion protein - Nature Methods 2007 Aug; 4(8): 645-50
AXKI - Caughey,B. - Prion Protein Aggregation, Amplification and Inhibition - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Invited Speakers S1.1
AWZM - Kocisko,D.A.; Bertholet,N.; Moore,R.A.; Caughey,B.; Vaillant,A. - Identification of prion inhibitors by a fluorescence-polarization-based competitive binding assay - Analytical Biochemistry 2007 Apr 1; 363(1): 154-6
AWXV - Raymond,G.J.; Raymond,L.D.; Meade-White,K.D.; Hughson,A.G.; Favara,C.; Gardner,D.; Williams,E.S.; Miller,M.W.; Race,R.E.; Caughey,B. - Transmission and adaptation of chronic wasting disease to hamsters and transgenic mice: evidence for strains. - Journal of Virology 2007 Apr; 81(8): 4305-14
AXXC - Steele,A.; Jackson,W.; Hutter,G.; Aguzzi,A.; King,O.; Raymond,G.; Caughey,B.; Lindquist,S. - A Critical Role for Heat Shock Factor 1 in Prion Pathogenesis - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Oral Abstracts FC4.8
AVAL - Atarashi,R.; Sim,V.L.; Nishida,N.; Caughey,B.W.; Katamine,S. - Prion strain-dependent differences in conversion of mutant prion proteins in cell culture - Journal of Virology 2006 Aug; 80(16): 7854-62
ATYX - Baron,G.S.; Magalhaes,A.C.; Prado,M.A.; Caughey,B.W. - Mouse-adapted scrapie infection of SN56 cells: greater efficiency with microsome-associated versus purified PrP-res. - Journal of Virology 2006 Mar; 80(5): 2106-17
ANLA - Baron,G.S.; Caughey,B.W. - Effect of glycosylphosphatidylinositol anchor-dependent and -independent prion protein association with model raft membranes on conversion to the protease-resistant isoform - The Journal of Biological Chemistry 2003 Apr 25; 278(17): 14883-92
AAZT - Baron,G.S.; Wehrly,K.; Dorward,D.W.; Chesebro,B.; Caughey,B.W. - Conversion of raft associated prion protein to the protease-resistant state requires insertion of PrPres (PrPsc) into contiguous membranes - EMBO Journal 2002 Mar 1; 21(5): 1031-40
ABHT - Bessen,R.A.; Raymond,G.J.; Caughey,B.W. - In situ formation of protease-resistant prion protein in transmissible spongiform encephalopathy-infected brain slices - The Journal of Biological Chemistry 1997 Jun 13; 272(24): 15227-31
AODT - Bessen,R.A.; Kocisko,D.A.; Raymond,G.J.; Marsh,R.F.; Lansbury,P.T.Jr.; Caughey,B.W. - Strain-specific cell-free formation of the prion protein - Journal of Cellular Biochemistry 1995; 1995(S21B): 101
ABHU - Bessen,R.A.; Kocisko,D.A.; Raymond,G.J.; Nandan,S.; Lansbury,P.T.Jr.; Caughey,B.W. - Non-genetic propagation of strain-specific properties of scrapie prion protein - Nature 1995 Jun 22; 375(6533): 698-700
ABNP - Bossers,A.; Belt,P.B.G.M.; Raymond,G.J.; Caughey,B.W.; de Vries,R.; Smits,M.A. - Scrapie susceptibility-linked polymorphisms modulate the in vitro conversion of sheep prion protein to protease-resistant forms - Proceedings of the National Academy of Sciences of the United States of America 1997 May 13; 94(10): 4931-6
ACDW - Callahan,M.A.; Xiong,L.; Caughey,B.W. - Reversibility of scrapie-associated prion protein aggregation - The Journal of Biological Chemistry 2001 Jul 27; 276(30): 28022-8
ARBW - Cashman,N.R.; Caughey,B.W. - Prion diseases - close to effective therapy? - Nature Reviews. Drug Discovery 2004 Oct; 3(10): 874-84
AVHC - Caughey,B.W.; Baron,G.S. - Prions and their partners in crime - Nature 2006 Oct 19; 443(7113): 803-10
AWDB - Caughey,B.W. - Structure, trafficking and inhibition of infectious scrapie particles - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Oral sessions ORAL-10
AWXS - Caughey,B.W.; Caughey,W.S.; Kocisko,D.A.; Lee,K.S.; Silveira,J.R.; Morrey,J.D. - Prions and transmissible spongiform encephalopathy (TSE) chemotherapeutics: A common mechanism for anti-TSE compounds? - Accounts of Chemical Research 2006 Sep; 39(9): 646-53
ATFW - Caughey,B.W. - The most infectious scrapie particle, neuronal traficking of PrP-RES, and effects of anchorless PrP on scrapie - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Oral sessions ORAL-27
APFX - Caughey,B.W.; Kocisko,D.A. - Prion diseases: a nucleic-acid accomplice? - Nature 2003 Oct 16; 425(6959): 673-4
APFY - Caughey,B.W. - Prion protein conversions: insight into mechanisms, TSE transmission barriers and strains. - British Medical Bulletin 2003; 66: 109-20
AORG - Caughey,B.W.; Kocisko,D.A.; Baron,G.S.; Speare,J.O.; Maxson,L. - Prion protein isoform interactions, inhibitors and TSE therapeutics - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Oral sessions OS-06
AOFH - Caughey,B.W. - Probing for prions: recognizing misfolded PrP. - Nature Medicine 2003 Jul; 9(7): 819-20
ANUF - Caughey,B.W.; Raymond,L.D.; Raymond,G.J.; Maxson,L.; Silveira,J.; Baron,G.S. - Inhibition of protease-resistant prion protein accumulation in vitro by curcumin - Journal of Virology 2003 May; 77(9): 5499-502
ANUG - Caughey,B.W.; Lansbury,P.T.Jr. - Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders. - Annual Review of Neuroscience 2003; 26: 267-98
ACJF - Caughey,B.W.; Baron,G.S. - Factors affecting interactions between prion protein isoforms - Biochemical Society Transactions 2002 Aug; 30(4): 565-9
ACJG - Caughey,B.W.; Chesebro,B. - Transmissible spongiform encephalopathies and prion protein interconversions - Advances in Virus Research 2001; 56: 277-311
ACJH - Caughey,B.W.; Raymond,G.J.; Callahan,M.A.; Wong,C.; Baron,G.S.; Xiong,L.W. - Interactions and conversions of prion protein isoforms - Advances in Protein Chemistry 2001; 57: 139-69
ACJI - Caughey,B.W. - Interactions between prion protein isoforms: the kiss of death? - Trends in Biochemical Sciences 2001 Apr; 26(4): 235-42
ACJJ - Caughey,B.W. - Prion protein interconversions - Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 2001 Feb 28; 356(1406): 197-200; discussion 200-2
ACJK - Caughey,B.W. - Formation of protease-resistant prion protein in cell-free systems - Current Issues in Molecular Biology 2000 Jul; 2(3): 95-101
ACJL - Caughey,B.W. - Transmissible spongiform encephalopathies, amyloidoses and yeast prions: common threads? - Nature Medicine 2000 Jul; 6(7): 751-4
ACJM - Caughey,B.W.; Raymond,G.J.; Priola,S.A.; Kocisko,D.A.; Race,R.E.; Bessen,R.A.; Lansbury,P.T.Jr.; Chesebro,B. - Methods for studying prion protein (PrP) metabolism and the formation of protease-resistant PrP in cell culture and cell-free systems. An update. - Molecular Biotechnology 1999 Nov; 13(1): 45-55
ACJN - Caughey,B.W.; Horiuchi,M.; Demaimay,R.; Raymond,G.J. - Assays of protease-resistant prion protein and its formation - Methods in Enzymology 1999; 309: 122-33
ACJO - Caughey,B.W.; Raymond,G.J.; Bessen,R.A. - Strain-dependent differences in beta-sheet conformations of abnormal prion protein - The Journal of Biological Chemistry 1998 Nov 27; 273(48): 32230-5
APNX - Caughey,B.W.; Chesebro,B. - Prion protein and the transmissible spongiform encephalopathies - Trends in Cell Biology 1997 Feb; 7(2): 56-62
ACJP - Caughey,B.W.; Raymond,G.J.; Kocisko,D.A.; Lansbury,P.T.Jr. - Scrapie infectivity correlates with converting activity, protease resistance, and aggregation of scrapie-associated prion protein in guanidine denaturation studies - Journal of Virology 1997 May; 71(5): 4107-10
APNY - Caughey,B.W.; Prusiner,S.B. - Cell-free conversion of protease-sensitive prion protein to the protease-resistant state - requirement for aggregates of scrapie-associated prion protein - general discussion-iv - Ciba Foundation Symposia 1996; 199(): 202-4
ACJQ - Caughey,B.W.; Kocisko,D.A.; Raymond,G.J.; Lansbury,P.T.Jr. - Aggregates of scrapie-associated prion protein induce the cell-free conversion of protease-sensitive prion protein to the protease-resistant state - Chemistry and Biology 1995 Dec; 2(12): 807-17
APNZ - Caughey,B.W.; Brown,K.; Raymond,G.J.; Katzenstein,G.E.; Thresher,W. - Binding of the protease-sensitive form of PrP (Prion protein) to sulfated glycosaminoglycan and congo red (vol 68, pg 2135, 1994) - Journal of Virology 1994 Jun; 68(6): 4107
ACJR - Caughey,B.W.; Race,R.E. - Scrapie-associated PrP accumulation and its inhibition: revisiting the amyloid-glycosaminoglycan connection. - Slow Infections of the Central Nervous System (Ed. Bjornsson, J.; Carp, R.I.; Love, A.; Wisniewski, H.M.) 1994 Jun 6; 724 : 290-295
ACJS - Caughey,B.W.; Brown,K.; Raymond,G.J.; Katzenstein,G.E.; Thresher,W. - Binding of the protease-sensitive form of PrP (prion protein) to sulfated glycosaminoglycan and congo red [corrected] - Journal of Virology 1994 Apr; 68(4): 2135-41
ACJT - Caughey,B.W. - Scrapie-associated PrP accumulation and agent replication: effects of sulphated glycosaminoglycan analogues. - Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 1994 Mar 29; 343(1306): 399-404
ACJU - Caughey,B.W. - Protease-resistant PrP accumulation and scrapie agent replication: a role for sulphated glycosaminoglycans? - Biochemical Society Transactions 1994 Feb; 22(1): 163-7
ACJV - Caughey,B.W. - Scrapie associated PrP accumulation and its prevention: insights from cell culture. - British Medical Bulletin 1993 Oct; 49(4): 860-72
ACJW - Caughey,B.W.; Ernst,D.; Race,R.E. - Congo red inhibition of scrapie agent replication - Journal of Virology 1993 Oct; 67(10): 6270-2
ACJX - Caughey,B.W.; Raymond,G.J. - Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells - Journal of Virology 1993 Feb; 67(2): 643-50
ACJY - Caughey,B.W.; Race,R.E. - Potent inhibition of scrapie-associated PrP accumulation by congo red - Journal of Neurochemistry 1992 Aug; 59(2): 768-71
ACJZ - Caughey,B.W.; Raymond,G.J.; Ernst,D.; Race,R.E. - N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease(s): implications regarding the site of conversion of PrP to the protease-resistant state. - Journal of Virology 1991 Dec; 65(12): 6597-603
ACKA - Caughey,B.W.; Raymond,G.J. - The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive - The Journal of Biological Chemistry 1991 Sep 25; 266(27): 18217-23
ACKI - Caughey,B.W.; Dong,A.; Bhat,K.S.; Ernst,D.; Hayes,S.F.; Caughey,W.S. - Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy - Biochemistry 1991 Aug 6; 30(31): 7672-80
ACKB - Caughey,B.W. - In vitro expression and biosynthesis of prion protein - Current Topics in Microbiology and Immunology 1991; 172: 93-107
ACKC - Caughey,B.W.; Neary,K.; Buller,R.; Ernst,D.; Perry,L.L.; Chesebro,B.; Race,R.E. - Normal and scrapie-associated forms of prion protein differ in their sensitivities to phospholipase and proteases in intact neuroblastoma cells - Journal of Virology 1990 Mar; 64(3): 1093-101
ACKD - Caughey,B.W.; Race,R.E.; Chesebro,B. - Comparative sequence analysis, in vitro expression and biosynthesis of mouse PrP - Progress in Clinical and Biological Research 1989; 317: 619-36
ACKE - Caughey,B.W.; Race,R.E.; Ernst,D.; Buchmeier,M.J.; Chesebro,B. - Prion protein biosynthesis in scrapie-infected and uninfected neuroblastoma cells - Journal of Virology 1989 Jan; 63(1): 175-81
ACKF - Caughey,B.W.; Race,R.E.; Vogel,M.; Buchmeier,M.J.; Chesebro,B. - In vitro expression in eukaryotic cells of a prion protein gene cloned from scrapie-infected mouse brain - Proceedings of the National Academy of Sciences of the United States of America 1988 Jul; 85(13): 4657-61
ACKG - Caughey,B.W.; Race,R.E.; Chesebro,B. - Detection of prion protein mRNA in normal and scrapie-infected tissues and cell lines - Journal of General Virology 1988 Mar; 69(3): 711-6
ACKH - Caughey,B.W.; Race,R.E.; Vogel,M.; Buchmeier,M.J.; Chesebro,B. - In vitro expression of cloned PrP cDNA derived from scrapie-infected mouse brain: lack of transmission of scrapie infectivity. - Ciba Foundation Symposium 1988; 135: 197-208
ACKJ - Caughey,W.S.; Raymond,L.D.; Horiuchi,M.; Caughey,B.W. - Inhibition of protease-resistant prion protein formation by porphyrins and phthalocyanines - Proceedings of the National Academy of Sciences of the United States of America 1998 Oct 13; 95(21): 12117-22
ACLO - Chabry,J.; Caughey,B.W.; Chesebro,B. - Specific inhibition of in vitro formation of protease-resistant prion protein by synthetic peptides - The Journal of Biological Chemistry 1998 May 22; 273(21): 13203-7
ASLY - Chesebro,B.; Trifilo,M.; Race,R.E.; Meade-White,K.; Teng,C.; LaCasse,R.; Raymond,L.D.; Favara,C.; Baron,G.S.; Priola,S.A.; Caughey,B.W.; Masliah,E.; Oldstone,M. - Anchorless prion protein results in infectious amyloid disease without clinical scrapie - Science 2005 Jun 3; 308(5727): 1435-9
ATBM - Chesebro,B.; Caughey,B.W. - Scrapie agent reflication without the prion protein? - Current Biology 1993 Oct 1; 3(10): 696-8
ACOM - Chesebro,B.; Wehrly,K.; Caughey,B.W.; Nishio,J.; Ernst,D.; Race,R.E. - Foreign PrP expression and scrapie infection in tissue culture cell lines - Developments in Biological Standardization 1993; 80: 131-40
ADEH - DebBurman,S.K.; Raymond,G.J.; Caughey,B.W.; Lindquist,S.L. - Chaperone-supervised conversion of prion protein to its protease-resistant form - Proceedings of the National Academy of Sciences of the United States of America 1997 Dec 9; 94(25): 13938-43
ADFY - Demaimay,R.; Chesebro,B.; Caughey,B.W. - Inhibition of formation of protease-resistant prion protein by Trypan Blue, Sirius Red and other Congo Red analogs - Archives of Virology. Supplementum 2000(16): 277-83
ADGA - Demaimay,R.; Harper,J.; Gordon,H.; Weaver,D.; Chesebro,B.; Caughey,B.W. - Structural aspects of Congo red as an inhibitor of protease-resistant prion protein formation - Journal of Neurochemistry 1998 Dec; 71(6): 2534-41
AOFR - Dimcheff,D.E.; Portis,J.L.; Caughey,B.W. - Prion proteins meet protein quality control - Trends in Cell Biology 2003 Jul; 13(7): 337-40
ADML - Doh-ura,K.; Iwaki,T.; Caughey,B.W. - Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation - Journal of Virology 2000 May; 74(10): 4894-7
AFIT - Herrmann,L.M.; Caughey,B.W. - The importance of the disulfide bond in prion protein conversion - Neuroreport 1998 Aug 3; 9(11): 2457-61
AFNX - Horiuchi,M.; Baron,G.S.; Xiong,L.W.; Caughey,B.W. - Inhibition of interactions and interconversions of prion protein isoforms by peptide fragments from the C-terminal folded domain - The Journal of Biological Chemistry 2001 May 4; 276(18): 15489-97
AFNY - Horiuchi,M.; Priola,S.A.; Chabry,J.; Caughey,B.W. - Interactions between heterologous forms of prion protein: binding, inhibition of conversion, and species barriers. - Proceedings of the National Academy of Sciences of the United States of America 2000 May 23; 97(11): 5836-41
AFNZ - Horiuchi,M.; Caughey,B.W. - Prion protein interconversions and the transmissible spongiform encephalopathies - Structure with Folding and Design 1999 Oct 15; 7(10): R231-40
AFOA - Horiuchi,M.; Caughey,B.W. - Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state - EMBO Journal 1999 Jun 15; 18(12): 3193-203
AVNO - Kocisko,D.A.; Caughey,B.W.; Morrey,J.D.; Race,R.E. - Enhanced antiscrapie effect using combination drug treatment - Antimicrobial Agents and Chemotherapy 2006 Oct; 50(10): 3447-9
AUIA - Kocisko,D.A.; Vaillant,A.; Lee,K.S.; Arnold,K.M.; Bertholet,N.; Race,R.E.; Olsen,E.A.; Juteau,J.M.; Caughey,B.W. - Potent antiscrapie activities of degenerate phosphorothioate oligonucleotides - Antimicrobial Agents and Chemotherapy 2006 Mar; 50(3): 1034-44
AUBE - Kocisko,D.A.; Caughey,W.S.; Race,R.E.; Roper,G.; Caughey,B.W.; Morrey,J.D. - A porphyrin increases survival time of mice after intracerebral prion infection - Antimicrobial Agents and Chemotherapy 2006 Feb; 50(2): 759-61
ATXC - Kocisko,D.A.; Caughey,B.W. - Mefloquine, an antimalaria drug with antiprion activity in vitro, lacks activity in vivo - Journal of Virology 2006 Jan; 80(2): 1044-6
AVIX - Kocisko,D.A.; Caughey,B.W. - Searching for anti-prion compounds: cell-based high-throughput in vitro assays and animal testing strategies. - Methods in Enzymology 2006; 412: 223-34
ASZW - Kocisko,D.A.; Engel,A.L.; Harbuck,K.; Arnold,K.M.; Olsen,E.A.; Raymond,L.D.; Vilette,D.; Caughey,B.W. - Comparison of protease-resistant prion protein inhibitors in cell cultures infected with two strains of mouse and sheep scrapie - Neuroscience Letters 2005 Nov 11; 388(2): 106-11
AQWE - Kocisko,D.A.; Morrey,J.D.; Race,R.E.; Chen,J.; Caughey,B.W. - Evaluation of new cell culture inhibitors of protease-resistant prion protein against scrapie infection in mice - Journal of General Virology 2004 Aug; 85(8): 2479-83
AOOI - Kocisko,D.A.; Baron,G.S.; Rubenstein,R.; Chen,J.; Kuizon,S.; Caughey,B.W. - New inhibitors of scrapie-associated prion protein formation in a library of 2000 drugs and natural products - Journal of Virology 2003 Oct; 77(19): 10288-94
AGQB - Kocisko,D.A.; Lansbury,P.T.Jr.; Caughey,B.W. - Partial unfolding and refolding of scrapie-associated prion protein: evidence for a critical 16-kDa C-terminal domain. - Biochemistry 1996 Oct 15; 35(41): 13434-42
AGQC - Kocisko,D.A.; Priola,S.A.; Raymond,G.J.; Chesebro,B.; Lansbury,P.T.Jr.; Caughey,B.W. - Species specificity in the cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barrier. - Proceedings of the National Academy of Sciences of the United States of America 1995 Apr 25; 92(9): 3923-7
AGQD - Kocisko,D.A.; Come,J.H.; Priola,S.A.; Chesebro,B.; Raymond,G.J.; Lansbury,P.T.Jr.; Caughey,B.W. - Cell-free formation of protease-resistant prion protein - Nature 1994 Aug 11; 370(6489): 471-4
AHAB - Lansbury,P.T.Jr.; Caughey,B.W. - The double life of the prion protein - Current Biology 1996 Aug 1; 6(8): 914-6
AHAC - Lansbury,P.T.Jr.; Caughey,B.W. - The chemistry of scrapie infection: implications of the 'ice 9' metaphor. - Chemistry and Biology 1995 Jan; 2(1): 1-5
AVBL - Lima,L.M.T.R.; Cordeiro,Y.; Tinoco,L.W.; Marques,A.F.; Oliveira,C.L.; Sampath,S.; Kodali,R.; Choi,G.; Foguel,D.; Torriani,I.; Caughey,B.W.; Silva,J.L. - Structural insights into the interaction between prion protein and nucleic acid - Biochemistry 2006 Aug 1; 45(30): 9180-7
AUBO - Magalhaes,A.C.; Baron,G.S.; Lee,K.S.; Steele-Mortimer,O.; Dorward,D.; Prado,M.A.; Caughey,B.W. - Uptake and neuritic transport of scrapie prion protein coincident with infection of neuronal cells - Journal of Neuroscience 2005 May 25; 25(21): 5207-16
APJW - Maxson,L.; Wong,C.; Herrmann,L.M.; Caughey,B.W.; Baron,G.S. - A solid-phase assay for identification of modulators of prion protein interactions - Analytical Biochemistry 2003 Dec 1; 323(1): 54-64
AIUW - Neary,K.; Caughey,B.W.; Ernst,D.; Race,R.E.; Chesebro,B. - Protease sensitivity and nuclease resistance of the scrapie agent propagated in vitro in neuroblastoma cells - Journal of Virology 1991 Feb; 65(2): 1031-4
AOCD - Priola,S.A.; Chesebro,B.; Caughey,B.W. - Biomedicine. A view from the top - prion diseases from 10,000 feet. - Science 2003 May 9; 300(5621): 917-9
AJPK - Priola,S.A.; Caughey,B.W.; Caughey,W.S. - Novel therapeutic uses for porphyrins and phthalocyanines in the transmissible spongiform encephalopathies - Current Opinion in Microbiology 1999 Oct; 2(5): 563-6
AJPP - Priola,S.A.; Caughey,B.W.; Wehrly,K.; Chesebro,B. - A 60-kDa prion protein (PrP) with properties of both the normal and scrapie-associated forms of PrP - The Journal of Biological Chemistry 1995 Feb 17; 270(7): 3299-305
AJPQ - Priola,S.A.; Caughey,B.W.; Race,R.E.; Chesebro,B. - Heterologous PrP molecules interfere with accumulation of protease-resistant PrP in scrapie-infected murine neuroblastoma cells - Journal of Virology 1994 Aug; 68(8): 4873-8
AJPR - Priola,S.A.; Caughey,B.W. - Inhibition of scrapie-associated PrP accumulation. Probing the role of glycosaminoglycans in amyloidogenesis. - Molecular Neurobiology 1994 Apr-Jun; 8(2-3): 113-20
AJPS - Priola,S.A.; Caughey,B.W.; Raymond,G.J.; Chesebro,B. - Prion protein and the scrapie agent: in vitro studies in infected neuroblastoma cells. - Infectious Agents and Disease 1994 Apr-Jun; 3(2-3): 54-8
AJUE - Race,R.E.; Meade-White,K.; Raines,A.; Raymond,G.J.; Caughey,B.W.; Chesebro,B. - Subclinical Scrapie Infection in a Resistant Species: Persistence, Replication, and Adaptation of Infectivity during Four Passages. - Journal of Infectious Diseases 2002 Dec 1; 186 Suppl 2: S166-70
AJUF - Race,R.E.; Raines,A.; Raymond,G.J.; Caughey,B.W.; Chesebro,B. - Long-term subclinical carrier state precedes scrapie replication and adaptation in a resistant species: analogies to bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease in humans. - Journal of Virology 2001 Nov; 75(21): 10106-12
AJUJ - Race,R.E.; Ernst,D.; Jenny,A.; Taylor,W.; Sutton,D.; Caughey,B.W. - Diagnostic implications of detection of proteinase K-resistant protein in spleen, lymph nodes, and brain of sheep - American Journal of Veterinary Research 1992 Jun; 53(6): 883-9
AJUQ - Race,R.E.; Graham,K.; Ernst,D.; Caughey,B.W.; Chesebro,B. - Analysis of linkage between scrapie incubation period and the prion protein gene in mice - Journal of General Virology 1990 Feb; 71(2): 493-7
AJUR - Race,R.E.; Caughey,B.W.; Graham,K.; Ernst,D.; Chesebro,B. - Analyses of frequency of infection, specific infectivity, and prion protein biosynthesis in scrapie-infected neuroblastoma cell clones - Journal of Virology 1988 Aug; 62(8): 2845-9
ATXK - Raymond,G.J.; Olsen,E.A.; Lee,K.S.; Raymond,L.D.; Bryant,P.K.3rd; Baron,G.S.; Caughey,W.S.; Kocisko,D.A.; McHolland,L.E.; Favara,C.; Langeveld,J.P.M.; van Zijderveld,F.G.; Mayer,R.T.; Miller,M.W.; Williams,E.S.; Caughey,B.W. - Inhibition of protease-resistant prion protein formation in a transformed deer cell line infected with chronic wasting disease - Journal of Virology 2006 Jan; 80(2): 596-604
AJWU - Raymond,G.J.; Bossers,A.; Raymond,L.D.; O'Rourke,K.I.; McHolland,L.E.; Bryant,P.K.3rd; Miller,M.W.; Williams,E.S.; Smits,M.; Caughey,B.W. - Evidence of a molecular barrier limiting susceptibility of humans, cattle and sheep to chronic wasting disease - EMBO Journal 2000 Sep 1; 19(17): 4425-30
AJWV - Raymond,G.J.; Hope,J.; Kocisko,D.A.; Priola,S.A.; Raymond,L.D.; Bossers,A.; Ironside,J.; Will,R.G.; Chen,S.G.; Petersen,R.B.; Gambetti,P.; Rubenstein,R.; Smits,M.A.; Lansbury,P.T.Jr.; Caughey,B.W. - Molecular assessment of the potential transmissibilities of BSE and scrapie to humans - Nature 1997 Jul 17; 388(6639): 285-8
AWNO - Sethi,J.; Lohman,K.; Silveira,J.; Caughey,B.W.; Rudolph,A.; Orser,C. - Defining interactions between pronucleonTM conformational ligands and the optimal aggregation state of PrP(TSE) substrates for the misfolded protein diagnostic (MPD) assay - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions S-20
AVJG - Silveira,J.R.; Hughson,A.G.; Caughey,B.W. - Fractionation of prion protein aggregates by asymmetrical flow field-flow fractionation - Methods in Enzymology 2006; 412: 21-33
ASXY - Silveira,J.R.; Raymond,G.J.; Hughson,A.G.; Race,R.E.; Sim,V.L.; Hayes,S.F.; Caughey,B.W. - The most infectious prion protein particles - Nature 2005 Sep 8; 437(7056): 257-61
AQPA - Silveira,J.R.; Caughey,B.W.; Baron,G.S. - Prion protein and the molecular features of transmissible spongiform encephalopathy agents - Current Topics in Microbiology and Immunology 2004; 284: 1-50
ANGC - Speare,J.O.; Rush,T.S.3rd; Bloom,M.E.; Caughey,B.W. - The role of helix 1 aspartates and salt bridges in the stability and conversion of prion protein - The Journal of Biological Chemistry 2003 Apr 4; 278(14): 12522-9
AVPX - Tahiri-Alaoui,A.; Sim,V.L.; Caughey,B.W.; James,W. - Molecular heterosis of prion protein beta-oligomers: A potential mechanism of human resistance to disease. - The Journal of Biological Chemistry 2006 Nov 10; 281(45): 34171-8
ALWA - Uptain,S.M.; Sawicki,G.J.; Caughey,B.W.; Lindquist,S.L. - Strains of [PSI(+)] are distinguished by their efficiencies of prion-mediated conformational conversion - EMBO Journal 2001 Nov 15; 20(22): 6236-45
AMGW - Weber,D.J.; McFadden,P.N.; Caughey,B.W. - Measurement of altered aspartyl residues in the scrapie associated form of prion protein - Biochemical and Biophysical Research Communications 1998 May 29; 246(3): 606-8
AMIX - Welker,E.; Raymond,L.D.; Scheraga,H.A.; Caughey,B.W. - Intramolecular versus intermolecular disulfide bonds in prion proteins - The Journal of Biological Chemistry 2002 Sep 6; 277(36): 33477-81
AMSA - Wong,C.; Xiong,L.W.; Horiuchi,M.; Raymond,L.D.; Wehrly,K.; Chesebro,B.; Caughey,B.W. - Sulfated glycans and elevated temperature stimulate PrPsc-dependent cell-free formation of protease-resistant prion protein - EMBO Journal 2001 Feb 1; 20(3): 377-86
AMTT - Xiong,L.W.; Raymond,L.D.; Hayes,S.F.; Raymond,G.J.; Caughey,B.W. - Conformational change, aggregation and fibril formation induced by detergent treatments of cellular prion protein - Journal of Neurochemistry 2001 Nov; 79(3): 669-78
AWXS - Caughey,B.W.; Caughey,W.S.; Kocisko,D.A.; Lee,K.S.; Silveira,J.R.; Morrey,J.D. - Prions and transmissible spongiform encephalopathy (TSE) chemotherapeutics: A common mechanism for anti-TSE compounds? - Accounts of Chemical Research 2006 Sep; 39(9): 646-53
ACKI - Caughey,B.W.; Dong,A.; Bhat,K.S.; Ernst,D.; Hayes,S.F.; Caughey,W.S. - Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy - Biochemistry 1991 Aug 6; 30(31): 7672-80
ACKJ - Caughey,W.S.; Raymond,L.D.; Horiuchi,M.; Caughey,B.W. - Inhibition of protease-resistant prion protein formation by porphyrins and phthalocyanines - Proceedings of the National Academy of Sciences of the United States of America 1998 Oct 13; 95(21): 12117-22
AUBE - Kocisko,D.A.; Caughey,W.S.; Race,R.E.; Roper,G.; Caughey,B.W.; Morrey,J.D. - A porphyrin increases survival time of mice after intracerebral prion infection - Antimicrobial Agents and Chemotherapy 2006 Feb; 50(2): 759-61
AOMN - Priola,S.A.; Raines,A.; Caughey,W.S. - Prophylactic and therapeutic effects of phthalocyanine tetrasulfonate in scrapie-infected mice - Journal of Infectious Diseases 2003 Sep 1; 188(5): 699-705
AJPJ - Priola,S.A.; Raines,A.; Caughey,W.S. - Porphyrin and phthalocyanine antiscrapie compounds - Science 2000 Feb 25; 287(5457): 1503-6
AJPK - Priola,S.A.; Caughey,B.W.; Caughey,W.S. - Novel therapeutic uses for porphyrins and phthalocyanines in the transmissible spongiform encephalopathies - Current Opinion in Microbiology 1999 Oct; 2(5): 563-6
ATXK - Raymond,G.J.; Olsen,E.A.; Lee,K.S.; Raymond,L.D.; Bryant,P.K.3rd; Baron,G.S.; Caughey,W.S.; Kocisko,D.A.; McHolland,L.E.; Favara,C.; Langeveld,J.P.M.; van Zijderveld,F.G.; Mayer,R.T.; Miller,M.W.; Williams,E.S.; Caughey,B.W. - Inhibition of protease-resistant prion protein formation in a transformed deer cell line infected with chronic wasting disease - Journal of Virology 2006 Jan; 80(2): 596-604