AUGM - Appel,T.R.; Lucassen,R.W.; Groschup,M.H.; Joncic,M.; Beekes,M.; Riesner,D. - Acid inactivation of prions: efficient at elevated temperature or high acid concentration. - Journal of General Virology 2006 May; 87(5): 1385-94
AAXL - Baldauf,E.; Beekes,M.; Diringer,H. - Evidence for an alternative direct route of access for the scrapie agent to the brain bypassing the spinal cord - Journal of General Virology 1997 May; 78(5): 1187-97
AXJC - Beekes,M.; Schulz-Schaeffer,W.J.; Wrede,A.; Wemheuer,W.; Brenig,B.; Kratzel,C.; Lemmer,K.; Buschmann,A.; Groschup,M.H.; Terytze,K.; Peters,R.; Seidel,B.; Thomzig,A. - Detection of Pathological Prion Protein PrPsc in the Skin of Animals with Experimental or Natural Scrapie, and in Prion Contaminated Soil - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Epidemiology, Risk Assessment and Transmission P04.22
AYGQ - Beekes,M.; Zerr,I.; Groschup,M.H. - Prion research: past, present, and future. - Veterinary Microbiology 2007 Aug 31; 123(4): 285-6
AXDS - Beekes,M.; Lasch,P.; Naumann,D. - Analytical applications of Fourier transform-infrared (FT-IR) spectroscopy in microbiology and prion research - Veterinary Microbiology 2007 Aug 31; 123(4): 305-19
AWTZ - Beekes,M. - Prions and prion diseases - The FEBS Journal 2007 Feb; 274(3): 575
AWTY - Beekes,M.; McBride,P.A. - The spread of prions through the body in naturally acquired transmissible spongiform encephalopathies - The FEBS Journal 2007 Feb; 274(3): 588-605
AUQK - Beekes,M. - On the trail of prions: Tracking, Typing, and Inactivating TSE agents - TSE-Forum, 6. Kongress - Nationale TSE-Forschungsplattform, Greifswald 26.6.-28.6.2006, Vortrag V-03
ATGO - Beekes,M. - PrPsc routing to muscles and strain differentiation in experimental scrapie and BSE - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Oral sessions ORAL-45
AQHR - Beekes,M.; Mielke,M.; Pauli,G.; Baier,M.; Kurth,R. - Aspects of risk assessment and risk management of nosocomial transmission of classical and variant Creutzfeldt-Jakob disease with special attention to German regulations - Contributions to Microbiology 2004; 11: 117-35
AOQG - Beekes,M.; Thomzig,A.; Kratzel,C.; Lenz,G.; Mai,J.; Krüger,D.; Schulz-Schaeffer,W.J.; McBride,P.A. - Pathophysiology of peripheral PrPsc-routing in hamsters fed with scrapie - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Oral sessions OS-25
ANLD - Beekes,M.; Mielke,M.; Kurth,R. - [Clinical aspects of risk assessment and prevention of nosocomial transmission of classical and variant CJD] - Aspekte zur Risikoabschätzung und Prävention nosokomialer Übertragungen der klassischen und varianten CJK - Der Internist 2002 Jun; 43(6): 738, 741-8
ABDV - Beekes,M.; Kurth,R. - [BSE and Creutzfeldt-Jakob disease. Implication on health politics in Germany and Europe] - BSE und Creutzfeldt-Jakob-Krankheit - Gesundheitspolitische Bedeutung für die Bundesrepublik Deutschland und Europa - Deutsche medizinische Wochenschrift 2002 Feb 15; 127(7): 335-40
ABDW - Beekes,M.; McBride,P.A. - Early accumulation of pathological PrP in the enteric nervous system and gut-associated lymphoid tissue of hamsters orally infected with scrapie - Neuroscience Letters 2000 Jan 14; 278(3): 181-4
ABDX - Beekes,M.; Otto,M.; Wiltfang,J.; Bahn,E.; Poser,S.; Baier,M. - Late increase of serum S100 beta protein levels in hamsters after oral or intraperitoneal infection with scrapie - Journal of Infectious Diseases 1999 Aug; 180(2): 518-20
ABDY - Beekes,M.; McBride,P.A.; Baldauf,E. - Cerebral targeting indicates vagal spread of infection in hamsters fed with scrapie - Journal of General Virology 1998 Mar; 79(3): 601-7
ABDZ - Beekes,M.; Baldauf,E.; Diringer,H. - Sequential appearance and accumulation of pathognomonic markers in the central nervous system of hamsters orally infected with scrapie - Journal of General Virology 1996 Aug; 77(8): 1925-34
ABEA - Beekes,M.; Baldauf,E.; Cassens,S.; Diringer,H.; Keyes,P.; Scott,A.C.; Wells,G.A.H.; Brown,P.; Gibbs,C.J.Jr.; Gajdusek,D.C. - Western blot mapping of disease-specific amyloid in various animal species and humans with transmissible spongiform encephalopathies using a high-yield purification method - Journal of General Virology 1995 Oct; 76(10): 2567-76
AQKV - Bertram,J.; Mielke,M.; Beekes,M.; Lemmer,K.; Baier,M.; Pauli,G. - [Inactivation and removal of prions in producing medical products. A contribution to evaluation and declaration of possible methods] - Inaktivierung und Entfernung von Prionen bei der Aufbereitung von Medizinprodukten. Ein Beitrag zur Prüfung und Deklaration geeigneter Verfahren. - Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 2004 Jan; 47(1): 36-40
AQVH - Bieschke,J.G.; Weber,P.; Sarafoff,N.; Beekes,M.; Giese,A.; Kretzschmar,H.A. - Autocatalytic self-propagation of misfolded prion protein - Proceedings of the National Academy of Sciences of the United States of America 2004 Aug 17; 101(33): 12207-11
AOQK - Bieschke,J.G.; Weber,P.; Sarafoff,N.; Beekes,M.; Giese,A.; Kretzschmar,H.A. - Loss of infectivity in autocatalytic self-propagation of misfolded prion protein - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - BR-48
AUGW - Birkmann,E.; Schäfer,O.; Weinmann,N.; Dumpitak,C.; Beekes,M.; Jackman,R.; Thorne,L.; Riesner,D. - Detection of prion particles in samples of BSE and scrapie by fluorescence correlation spectroscopy without proteinase K digestion - Biological Chemistry 2006 Jan; 387(1): 95-102
ATBQ - Blümel,J.; Burger,R.; Gerlich,W.; Gürtler,L.; Heiden,M.; Hitzler,W.; Jansen,B.; Klamm,H.; Ludwig,W.D.; Montag-Lessing,T.; Offergeld,R.; Paessens,A.; Pauli,G.; Seitz,R.; Schlenkrich,U.; Schottstedt,V.; Willkommen,H.; Beekes,M.; Zerr,I. - Ar beits kreis Blut - [Variants of Creutzfeldt-Jakob disease. Opinion of the Working Group on Blood of the Federal Ministry for Health and Social Security] - Variante Creutzfeldt-Jakob-Krankheit. Stellungnahmen des Arbeitskreises Blut des Bundesministeriums für Gesundheit und Soziale Sicherung. - Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 2005 Sep; 48(9): 1082-90
AXKT - De Pascalis,A.; Cardone,F.; Berardi,V.; Valanzano,A.; Graziano,S.; Abdel-Haq,H.; Heinz,V.; Buchow,R.; Mathys,A.; Beekes,M.; Knorr,D.; Meyer,R.; Pocchiari,M.; Brown,P. - High Pressure/Temperature Inactivation of TSE Agents in Specified Risk Materials - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Epidemiology, Risk Assessment and Transmission P04.81
ADKU - Diringer,H.; Roehmel,J.; Beekes,M. - Effect of repeated oral infection of hamsters with scrapie - Journal of General Virology 1998 Mar; 79(3): 609-12
ADKV - Diringer,H.; Beekes,M.; Özel,M.; Simon,D.; Queck,I.; Cardone,F.; Pocchiari,M.; Ironside,J.W. - Highly infectious purified preparations of disease-specific amyloid of transmissible spongiform encephalopathies are not devoid of nucleic acids of viral size - Intervirology 1997; 40(4): 238-46
ADKY - Diringer,H.; Beekes,M.; Oberdieck,U. - The nature of the scrapie agent: The virus theory. - Annals of the New York Academy of Sciences 1994 Jun 6; 724: 246-58
ADKZ - Diringer,H.; Oberdieck,U.; Malchow,M.; Beekes,M. - Transmissible spongiform encephalopathies: virally transmitted amyloidoses. - Developments in Biological Standardization 1993; 80: 25-9
ATZW - Dumpitak,C.; Beekes,M.; Weinmann,N.; Metzger,S.; Winklhofer,K.F.; Tatzelt,J.; Riesner,D. - The polysaccharide scaffold of PrP 27-30 is a common compound of natural prions and consists of alpha-linked polyglucose - Biological Chemistry 2005 Nov; 386(11): 1149-55
AUQQ - Giese,A.; Weber,P.; Piening,N.; Mitteregger,G.; Thomzig,A.; Beekes,M.; Kretzschmar,H.A. - Cell-free formation of misfolded prion protein with genuine prion infectivity - TSE-Forum, 6. Kongress - Nationale TSE-Forschungsplattform, Greifswald 26.6.-28.6.2006, Vortrag V-09
ATFR - Giese,A.; Weber,P.; Piening,N.; Thomzig,A.; Beekes,M.; Kretzschmar,H.A. - Cell-free generation of prion infectivity by serial PMCA - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Oral sessions ORAL-22
AEXE - Groschup,M.H.; Beekes,M.; McBride,P.A.; Hardt,M.; Hainfellner,J.A.; Budka,H. - Deposition of disease-associated prion protein involves the peripheral nervous system in experimental scrapie - Acta Neuropathologica 1999 Nov; 98(5): 453-7
AQLP - Kneipp,J.; Miller,L.M.; Spassov,S.; Sokolowski,F.; Lasch,P.; Beekes,M.; Naumann,D. - Scrapie-infected cells, isolated prions, and recombinant prion protein: a comparative study. - Biopolymers 2004 May-Jun 5; 74(1-2): 163-7
APIS - Kneipp,J.; Miller,L.M.; Joncic,M.; Kittel,M.; Lasch,P.; Beekes,M.; Naumann,D. - In situ identification of protein structural changes in prion-infected tissue - Biochimica et Biophysica Acta 2003 Nov 20; 1639(3): 152-8
AGPD - Kneipp,J.; Beekes,M.; Lasch,P.; Naumann,D. - Molecular changes of preclinical scrapie can be detected by infrared spectroscopy - Journal of Neuroscience 2002 Apr 15; 22(8): 2989-97
AGPE - Kneipp,J.; Lasch,P.; Baldauf,E.; Beekes,M.; Naumann,D. - Detection of pathological molecular alterations in scrapie-infected hamster brain by Fourier transform infrared (FT-IR) spectroscopy - Biochimica et Biophysica Acta 2000 Jun 15; 1501(2-3): 189-99
AVUS - Kratzel,C.; Mai,J.; Madela,K.; Beekes,M.; Krüger,D. - Propagation of scrapie in peripheral nerves after footpad infection in normal and neurotoxin exposed hamsters - Veterinary Research 2007 Jan-Feb; 38(1): 127-39
ARDN - Kratzel,C.; Mai,J.; Madela,K.; Schulz-Schaeffer,W.J.; Beekes,M. - Infektionsausbreitung im peripheren Nervensystem von scrapie-infizierten Hamstern: Befunde nach Desorganisation axonaler Zytoskelettkomponenten durch ß, ß'-iminodiproprionitril (IDPN) - TSE-Forum, 4. Kongress - Nationale TSE-Forschungsplattform, Düsseldorf 28.10.-29.10.2004, Poster PATH-01
AVGX - Kretlow,A.; Wang,Q.; Kneipp,J.; Lasch,P.; Beekes,M.; Miller,L.; Naumann,D. - FTIR-microspectroscopy of prion-infected nervous tissue - Biochimica et Biophysica Acta 2006 Jul; 1758(7): 948-59
AREB - Kretlow,A.; Wang,Q.; Beekes,M.; Miller,L.; Naumann,D. - In situ characterization of prion protein structure and metal accumulation in scrapie-infected cells by synchrotron infrared and x-ray microspectroscopy - TSE-Forum, 4. Kongress - Nationale TSE-Forschungsplattform, Düsseldorf 28.10.-29.10.2004, Poster GL-10
AOVE - Krüger,D.; Lenz,G.; Thomzig,A.; Beekes,M. - Monitoring the Gut Wall of Hamsters Fed with Scrapie - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - PG-10
AWYG - Lasch,P.; Beekes,M.; Schmitt,J.; Naumann,D. - Detection of preclinical scrapie from serum by infrared spectroscopy and chemometrics - Analytical and Bioanalytical Chemistry 2007 Mar; 387(5): 1791-800
APJF - Lasch,P.; Schmitt,J.; Beekes,M.; Udelhoven,T.; Eiden,M.; Fabian,H.; Petrich,W.; Naumann,D. - Antemortem identification of bovine spongiform encephalopathy from serum using infrared spectroscopy - Analytical Chemistry 2003 Dec 1; 75(23): 6673-8
AOVM - Lasch,P.; Schmitt,J.; Beekes,M.; Udelhoven,T.; Eiden,M.; Fabian,H.; Petrich,W.; Naumann,D. - Ante mortem identification of BSE from serum by infrared spectroscopy - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - DG-16
ATJF - Lemmer,K.; Mielke,M.; Kratzel,C.; Joncic,M.; Kampf,K.; Borchers,U.; Pauli,G.; Beekes,M. - Prion-decontamination of surgical instruments: Comparison of in vivo and in vitro results - A follow up study - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Decontamination DEC-12
ARIH - Lemmer,K.; Mielke,M.; Pauli,G.; Beekes,M. - Decontamination of surgical instruments from prion proteins: in vitro studies on the detachment, destabilization and degradation of PrPsc bound to steel surfaces. - Journal of General Virology 2004 Dec; 85(12): 3805-16
AREZ - Lemmer,K.; Mielke,M.; Pauli,G.; Beekes,M. - In vitro-Studien zur materialverträglichen Dekontamination von PrPsc-kontaminierten Stahloberflächen - TSE-Forum, 4. Kongress - Nationale TSE-Forschungsplattform, Düsseldorf 28.10.-29.10.2004, Poster INAK-02
AOVT - Lemmer,K.; Mielke,M.; Pauli,G.; Beekes,M. - Prion-decontamination of surgical instruments: In vitro studies on the destabilization, degradation and removal of surface-bound PrPsc - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - IV-02
AUSQ - Löschner,C.; Thomzig,A.; Beekes,M. - Amplification of PrPres from hamster-adapted BSE- and Scrapie-strains by Protein Misfolding Cyclic Amplification (PMCA) - TSE-Forum, 6. Kongress - Nationale TSE-Forschungsplattform, Greifswald 26.6.-28.6.2006, Poster: Diagnostik DIA-06
AIDP - McBride,P.A.; Schulz-Schaeffer,W.J.; Donaldson,M.I.; Bruce,M.E.; Diringer,H.; Kretzschmar,H.A.; Beekes,M. - Early spread of scrapie from the gastrointestinal tract to the central nervous system involves autonomic fibers of the splanchnic and vagus nerves - Journal of Virology 2001 Oct; 75(19): 9320-7
AYFH - McBride,P.A.; Donaldson,M.I.; Beekes,M. - Evidence that spread of scrapie from the gastrointestinal tract to the CNS involves transport along autonomic fibres of the splanchnic and vagus nerves - Research in Veterinary Science 2000 Jun; 68(Suppl.1): 20, NE06
AIDQ - McBride,P.A.; Beekes,M. - Pathological PrP is abundant in sympathetic and sensory ganglia of hamsters fed with scrapie - Neuroscience Letters 1999 Apr 16; 265(2): 135-8
AJCH - Otto,M.; Beekes,M.; Wiltfang,J.; Bahn,E.; Poser,S.; Diringer,H. - Elevated levels of serum S100 beta protein in scrapie hamsters - Journal of Neurovirology 1998 Oct; 4(5): 572-3
AVNW - Piening,N.; Weber,P.; Högen,T.; Beekes,M.; Kretzschmar,H.A.; Giese,A. - Photo-induced crosslinking of prion protein oligomers and prions - Amyloid 2006 Jun; 13(2): 67-77
AKNR - Schmitt,J.; Beekes,M.; Brauer,A.; Udelhoven,T.; Lasch,P.; Naumann,D. - Identification of scrapie infection from blood serum by Fourier transform infrared spectroscopy - Analytical Chemistry 2002 Aug 1; 74(15): 3865-8
AXCJ - Seidel,B.; Thomzig,A.; Buschmann,A.; Groschup,M.H.; Peters,R.; Beekes,M.; Terytze,K. - Scrapie Agent (Strain 263K) can transmit disease via the oral route after persistence in soil over years - PLoS ONE 2007; 2: e435
AUZW - Spassov,S.; Beekes,M.; Naumann,D. - Structural differences between TSEs strains investigated by FT-IR spectroscopy - Biochimica et Biophysica Acta 2006 Jul; 1760(7): 1138-49
AWON - Strammiello,R.; Cescatti,M.; Farquhar,C.; Marshall,A.; Mai,J.; Beekes,M.; Parchi,P. - Physico-chemical properties of PrPres in peripheral tissues of experimental TSEs - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions PR-31
AWZY - Thomzig,A.; Schulz-Schaeffer,W.J.; Wrede,A.; Wemheuer,W.; Brenig,B.; Kratzel,C.; Lemmer,K.; Beekes,M. - Accumulation of pathological prion protein PrPsc in the skin of animals with experimental and natural scrapie - PLoS Pathogens 2007 May 25; 3(5): e66
AUBU - Thomzig,A.; Cardone,F.; Krüger,D.; Pocchiari,M.; Brown,P.; Beekes,M. - Pathological prion protein in muscles of hamsters and mice infected with rodent-adapted BSE or vCJD - Journal of General Virology 2006 Jan; 87(1): 251-4
ATPP - Thomzig,A.; Cardone,F.; Krüger,D.; Pocchiari,M.; Brown,P.W.; Beekes,M. - Pathological Prion Protein in Muscles of Rodents Infected with BSE or vCJD - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Pathogenesis PATH-26
ARCO - Thomzig,A.; Naumann,D.; Schulz-Schaeffer,W.J.; Beekes,M. - PrPsc in Muskeln und Stammdifferenzierung von TSE-Erregern - TSE-Forum, 4. Kongress - Nationale TSE-Forschungsplattform, Düsseldorf 28.10.-29.10.2004, Vortrag V-05
AQPR - Thomzig,A.; Spassov,S.; Friedrich,M.; Naumann,D.; Beekes,M. - Discriminating scrapie and bovine spongiform encephalopathy isolates by infrared spectroscopy of pathological prion protein - The Journal of Biological Chemistry 2004 Aug 6; 279(32): 33847-54
AQGZ - Thomzig,A.; Schulz-Schaeffer,W.J.; Kratzel,C.; Mai,J.; Beekes,M. - Preclinical deposition of pathological prion protein PrPsc in muscles of hamsters orally exposed to scrapie - Journal of Clinical Investigation 2004 May; 113(10): 1465-72
AOZU - Thomzig,A.; Diringer,H.; Beekes,M. - Clinico-Pathological and Biochemical Characteristics of a New BSE-Isolate in Hamsters - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - PG-08
ANVN - Thomzig,A.; Kratzel,C.; Lenz,G.; Krüger,D.; Beekes,M. - Widespread PrPsc accumulation in muscles of hamsters orally infected with scrapie - EMBO Reports 2003 May; 4(5): 530-3
AXYN - Weber,P.; Giese,A.; Piening,N.; Mitteregger,G.; Reznicek,L.; Thomzig,A.; Beekes,M.; Kretzschmar,H.A. - Size Matters - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Protein Misfolding P01.49
AXDU - Weber,P.; Giese,A.; Piening,N.; Mitteregger,G.; Thomzig,A.; Beekes,M.; Kretzschmar,H.A. - Generation of genuine prion infectivity by serial PMCA - Veterinary Microbiology 2007 Aug 31; 123(4): 346-57
AVOF - Weber,P.; Giese,A.; Piening,N.; Mitteregger,G.; Thomzig,A.; Beekes,M.; Kretzschmar,H.A. - Cell-free formation of misfolded prion protein with authentic prion infectivity - Proceedings of the National Academy of Sciences of the United States of America 2006 Oct 24; 103(43): 15818-23
AUSI - Weber,P.; Giese,A.; Piening,N.; Mitteregger,G.; Thomzig,A.; Beekes,M.; Kretzschmar,H.A. - Cell-free formation of misfolded prion protein with genuine prion infectivity - TSE-Forum, 6. Kongress - Nationale TSE-Forschungsplattform, Greifswald 26.6.-28.6.2006, Poster: Pathogenese/Infektion PATH-09
ATQL - Weber,P.; Piening,N.; Thomzig,A.; Beekes,M.; Kretzschmar,H.A.; Giese,A. - In vitro generated misfolded prion protein is infectious - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Structure of PrP and molecular determinants of infectivity STRCT-01
AXYY - Wrede,A.; Beekes,M.; Thomzig,A.; Schulz-Schaeffer,W.J. - Subcellular Localization of PrPsc in Muscle Fibres - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.12
ARCQ - Wrede,A.; Thomzig,A.; Beekes,M.; Schulz-Schaeffer,W.J. - Intramuskuläre Ausbreitung von PrPsc - TSE-Forum, 4. Kongress - Nationale TSE-Forschungsplattform, Düsseldorf 28.10.-29.10.2004, Vortrag V-07