ABHB - Bernad,P.G.; Gibbs,C.J.Jr.; Soyer,A.; Loscalzo,M.; Klein,A.E. - Creutzfeldt-Jakob disease diagnosable by EEG and cerebrospinal fluid analysis without brain biopsy: a case report. - Clinical Electroencephalography 1999 Oct; 30(4): 132-5
AJNF - Pollak,L.; Klein,C.; Giladi,R.; Kertesz,J.; Arlazoroff,A. - Progressive deterioration of brainstem auditory evoked potentials in Creutzfeldt-Jakob disease: clinical and electroencephalographic correlation. - Clinical Electroencephalography 1996 Apr; 27(2): 95-9
AUNT - Klein,F.; Lupo,T.; Pielack,D.; Mozola,M. - Validation study of a lateral-flow immunoassay for detection of ruminant by-product material in animal feeds and feed ingredients - Journal of AOAC International 2005 Nov-Dec; 88(6): 1583-92
ASZD - Kühne,M.; Klein,G.; Gasse,H. - Shortening of the Bovine Tongue According to Regulation (EC) 999/2001 is not Complying with the Current Legal Definition of Specified Risk Material - a Macroscopical and Histological Preliminary Study - Journal of Veterinary Medicine. Series B, Infectious Diseases and Veterinary Public Health 2005 Mar; 52(2): 102-4
AEBP - Fogden,M.; Whitehorn,K.; Starr,D.; Persaud,R.; Hannaford,R.; Barbara,J.A.J.; Love,E.; Robinson,A.; Ferguson,E.; Turner,G.; Wallington,T.; Klein,H.; Franklin,I.; Fry,R.; De Wit,J. - Panel Discussion. Millennium Festival of Medicine - Transfusion 2020 - 18 October 2000. - Transfusion Medicine 2001 Apr; 11(2): 136-45
APLB - Reesink,H.W.; Engelfriet,C.P.; Muylle,L.; Wendel,S.; Dickmeiss,E.; Krusius,T.; Maki,T.; Lin,C.K.; O'Riordan,J.; Prati,D.; Rebulla,P.; Shirato,T.; Nakajima,K.; Dupuis,H.M.; Flanagan,P.; Carasa,M.A.; Gallastegui,R.A.; Turek,P.; Hewitt,P.; Bernat,J.L.; Bianco,C.; Dodd,R.Y.; Klein,H.G. - Future counselling of donors and recipients of blood products concerning prion-related diseases - Vox Sanguinis 2003 Aug; 85(2): 126-48
AVTU - Thomas,A.V.; Klein,J.C.; Brockhaus-Dumke,A.; Heiss,W.D.; Jacobs,A.H.; Petereit,H.F. - [Fatal familial insomnia: case presentation and discussion of typical clinical and imaging findings] - Fatale familiäre Insomnie: Kasuistik zur Darstellung der klinischen und bildgebenden Befunde. - Der Nervenarzt 2006 Jun; 77(6): 711-5
AUUL - Thomas,A.V.; Klein,J.C.; Galldiks,N.; Hilker,R.; Grond,M.; Jacobs,A.H. - Multitracer PET imaging in Heidenhain variant of Creutzfeldt-Jakob disease - Journal of Neurology. Zeitschrift für Neurologie 2006 Feb; 253(2): 258-60
AACX - Aguzzi,A.; Brandner,S.; Fischer,M.B.; Furukawa,H.; Glatzel,M.; Hawkins,C.; Heppner,F.L.; Montrasio,F.; Navarro,B.; Parizek,P.; Pekarik,V.; Prinz,M.; Raeber,A.J.; Rockl,C.; Klein,M.A. - Spongiform encephalopathies: insights from transgenic models. - Advances in Virus Research 2001; 56: 313-52
AADB - Aguzzi,A.; Klein,M.A.; Montrasio,F.; Pekarik,V.; Brandner,S.; Furukawa,H.; Kaser,P.; Rockl,C.; Glatzel,M. - Prions: pathogenesis and reverse genetics. - Annals of the New York Academy of Sciences 2000; 920: 140-57
AADG - Aguzzi,A.; D'Angelo,M.G.; Klein,M.A.; Frigg,R.; Fischer,M.B.; Raeber,A.J.; Rockl,C.; Musahl,C.; Hegyi,I.; Brandner,S. - [The new research frontier on prion disease] - Le nuove frontiere della ricerca sulle malattie prioniche - Pathologica 1998 Dec; 90(6): 743-52
AADK - Aguzzi,A.; Klein,M.A.; Musahl,C.; Raeber,A.J.; Blättler,T.; Hegyi,I.; Frigg,R.; Brandner,S. - Use of brain grafts to study the pathogenesis of prion diseases - Essays in Biochemistry 1998; 33: 133-47
APBA - Aguzzi,A.; Weissmann,C.; Blättler,T.; Raeber,A.J.; Brandner,S.; Klein,M.A. - Prions - neurotoxicity and neuroinvasion - Naunyn-Schmiedebergs Archives of Pharmacology 1998; 358(N1): SB 11-B 11
AADM - Aguzzi,A.; Maddalena,A.; Brandner,S.; Klein,M.A. - [Molecular pathogenesis of spongiform encephalopathy] - Patogenesi molecolare delle encefalopatie spongiformi - Pathologica 1997 Oct; 89(5): 481-90
APBD - Aguzzi,A.; Bitiftler,T.; Klein,M.A.; Brandner,S.; Raeber,A.J.; Flechsig,E.; Weissmann,C. - Neurotoxicity and neuroinvasiveness of prions - Brain Pathology 1997; 7(N4): 1137-8
AADR - Aguzzi,A.; Blättler,T.; Klein,M.A.; Raeber,A.J.; Hegyi,I.; Frigg,R.; Brandner,S.; Weissmann,C. - Tracking prions: the neurografting approach. - Cellular and Molecular Life Science 1997 Jun; 53(6): 485-95
AADS - Aguzzi,A.; Raeber,A.J.; Blättler,T.; Flechsig,E.; Klein,M.A.; Weissmann,C.; Brandner,S. - Neurotoxicity and neuroinvasiveness of prions - Journal of Neurovirology 1997 May; 3 Suppl 1: S23-4
ATNR - Bach,P.; Flechsig,E.; Hoffmann,T.; Buchholz,C.J.; Klein,M.A.; Kalinke,U. - PrP-displaying retroparticles as a novel tool for mapping the fine specificity of antibodies binding to the cellular form of the prion protein - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Human prions, risk of blood products, and therapy HUMAN-15
AXIM - Bahlo,A.; Lindner,N.; Flechsig,E.; Klein,M.A. - Unaltered Neurodegeneration in Prion-infected Neurografts Devoid of BCL-2 or BAX - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.22
AUSB - Bahlo,A.; Lindner,N.; Flechsig,E.; Klein,M.A. - Unaltered neurodegeneration in prion-infected neurografts devoid of BCL-2 or BAX - TSE-Forum, 6. Kongress - Nationale TSE-Forschungsplattform, Greifswald 26.6.-28.6.2006, Poster: Pathogenese/Infektion PATH-02
ABKD - Blättler,T.; Brandner,S.; Raeber,A.J.; Klein,M.A.; Voigtländer,T.; Weissmann,C.; Aguzzi,A. - PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain - Nature 1997 Sep 4; 389(6646): 69-73
ABPU - Brandner,S.; Klein,M.A.; Frigg,R.; Pekarik,V.; Parizek,P.; Raeber,A.J.; Glatzel,M.; Schwarz,P.; Rülicke,T.; Weissmann,C.; Aguzzi,A. - Neuroinvasion of prions: insights from mouse models. - Experimental Physiology 2000 Nov; 85(6): 705-12
ABPV - Brandner,S.; Klein,M.A.; Aguzzi,A. - [Mechanisms of neuroinvasion by prions: molecular principles and present state of research] - Mechanismen der Neuroinvasion von Prionen: molekulare Grundlagen und aktueller Stand der Forschung. - Schweizerische medizinische Wochenschrift. Journal Suisse de Medecine 2000 Mar 25; 130(12): 435-42
ABPW - Brandner,S.; Klein,M.A.; Aguzzi,A. - A crucial role for B cells in neuroinvasive scrapie - Transfusion Clinique et Biologique 1999 Feb; 6(1): 17-23
AXLQ - Ermolayev,V.; Cathomen,T.; Klein,M.A.; Flechsig,E. - Prion Disease is Associated with Impaired Axonal Transport of Spinal Cord Projecting Motor Neurons in Mice - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.79
ATQD - Ermolayev,V.; Klein,M.A.; Flechsig,E. - Reduction of retrogradely labelled rubrospinal neurons correlates with onset of clinical prion disease in mice - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Pathogenesis PATH-40
ARGW - Ertmer,A.; Gilch,S.; Yun,S.W.; Flechsig,E.; Klebl,B.; Stein-Gerlach,M.; Klein,M.A.; Schätzl,H.M. - The tyrosine kinase inhibitor STI571 induces cellular clearance of PrPsc in prion-infected cells - The Journal of Biological Chemistry 2004 Oct 1; 279(40): 41918-27
AUQN - Flechsig,E.; Klein,M.A. - Immunotherapeutic approaches for intervention of prion diseases - TSE-Forum, 6. Kongress - Nationale TSE-Forschungsplattform, Greifswald 26.6.-28.6.2006, Vortrag V-06
AEFX - Frigg,R.; Klein,M.A.; Hegyi,I.; Zinkernagel,R.M.; Aguzzi,A. - Scrapie pathogenesis in subclinically infected B-cell-deficient mice - Journal of Virology 1999 Nov; 73(11): 9584-8
AEPR - Glatzel,M.; Brandner,S.; Klein,M.A.; Horstmann,S.; Aguzzi,A. - Prions - Role of the peripheral nervous system - Virus Research 2002 Jan 30; 82(1-2): 53
AEPW - Glatzel,M.; Klein,M.A.; Brandner,S.; Aguzzi,A. - Prions: from neurografts to neuroinvasion. - Archives of Virology. Supplementum 2000(16): 3-12
AFHY - Heppner,F.L.; Musahl,C.; Arrighi,I.; Klein,M.A.; Rülicke,T.; Oesch,B.; Zinkernagel,R.M.; Kalinke,U.; Aguzzi,A. - Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies - Science 2001 Oct 5; 294(5540): 178-82
AFHZ - Heppner,F.L.; Christ,A.D.; Klein,M.A.; Prinz,M.; Fried,M.; Kraehenbuhl,J.P.; Aguzzi,A. - Transepithelial prion transport by M cells - Nature Medicine 2001 Sep; 7(9): 976-7
ATOG - Hoffmann,T.; Ruoff,N.; Guenther,J.; Klein,M.A.; Flechsig,E. - Characterization of novel monoclonal antibodies against PrP - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Human prions, risk of blood products, and therapy HUMAN-30
ARET - Hoffmann,T.; Ruoff,N.; Günter,J.; Klein,M.A.; Flechsig,E. - Characterization of novel monoclonal antibodies against PrP for diagnostic and therapeutic approaches - TSE-Forum, 4. Kongress - Nationale TSE-Forschungsplattform, Düsseldorf 28.10.-29.10.2004, Poster THE-03
AGDD - Kaeser,P.S.; Klein,M.A.; Schwarz,P.; Aguzzi,A. - Efficient lymphoreticular prion propagation requires PrPc in stromal and hematopoietic cells - Journal of Virology 2001 Aug; 75(15): 7097-106
ARCP - Klein,M.A.; Remer,K.; Flechsig,E. - Neuro-immune interaction in peripheral prion pathogenesis - TSE-Forum, 4. Kongress - Nationale TSE-Forschungsplattform, Düsseldorf 28.10.-29.10.2004, Vortrag V-06
AOUU - Klein,M.A. - The neuroimmune connection in prion diseases - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Oral sessions OS-26
AGOG - Klein,M.A.; Kaeser,P.S.; Schwarz,P.; Weyd,H.; Xenarios,I.; Zinkernagel,R.M.; Carroll,M.C.; Verbeek,J.S.; Botto,M.; Walport,M.J.; Molina,H.; Kalinke,U.; Acha-Orbea,H.; Aguzzi,A. - Complement facilitates early prion pathogenesis - Nature Medicine 2001 Apr; 7(4): 488-92
AVUF - Klein,M.A. - Prion diseases and neuroinvasion - Schweizer Archiv für Neurologie und Psychiatrie. Archives Suisses de Neurologie et de Psychiatrie. Archivio Svizzero di Neurologia e Psichiatria 2001; 152(2): 50-4
AGOH - Klein,M.A.; Aguzzi,A. - The Neuroimmune Interface in Prion Diseases - News in Physiological Sciences : an International Journal of Physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society 2000 Oct; 15: 250-255
AGOI - Klein,M.A.; Frigg,R.; Raeber,A.J.; Flechsig,E.; Hegyi,I.; Zinkernagel,R.M.; Weissmann,C.; Aguzzi,A. - PrP expression in B lymphocytes is not required for prion neuroinvasion - Nature Medicine 1998 Dec; 4(12): 1429-33
AGOJ - Klein,M.A.; Frigg,R.; Flechsig,E.; Raeber,A.J.; Kalinke,U.; Bluethmann,H.; Bootz,F.; Suter,M.; Zinkernagel,R.M.; Aguzzi,A. - A crucial role for B cells in neuroinvasive scrapie - Nature 1997 Dec 18-25; 390(6661): 687-90
ANYL - Lötscher,M.; Recher,M.; Hunziker,L.; Klein,M.A. - Immunologically induced, complement-dependent up-regulation of the prion protein in the mouse spleen: follicular dendritic cells versus capsule and trabeculae. - Journal of Immunology 2003 Jun 15; 170(12): 6040-7
AINL - Montrasio,F.; Cozzio,A.; Flechsig,E.; Rossi,D.; Klein,M.A.; Rülicke,T.; Raeber,A.J.; Vosshenrich,C.A.; Proft,J.; Aguzzi,A.; Weissmann,C. - B lymphocyte-restricted expression of prion protein does not enable prion replication in prion protein knockout mice - Proceedings of the National Academy of Sciences of the United States of America 2001 Mar 27; 98(7): 4034-7
AINM - Montrasio,F.; Frigg,R.; Glatzel,M.; Klein,M.A.; Mackay,F.; Aguzzi,A.; Weissmann,C. - Impaired prion replication in spleens of mice lacking functional follicular dendritic cells - Science 2000 May 19; 288(5469): 1257-9
AVLL - Mossner,R.; Yun,S.W.; Lesch,K.P.; Gerlach,M.; Klein,M.A.; Riederer,P. - Unaltered susceptibility to scrapie in serotonin transporter deficient mice - Neurochemistry International 2006 Oct; 49(5): 454-8
AXDO - Nitschke,C.; Flechsig,E.; van den Brandt,J.; Lindner,N.; Lührs,T.; Dittmer,U.; Klein,M.A. - Immunisation strategies against prion diseases: prime-boost immunisation with a PrP DNA vaccine containing foreign helper T-cell epitopes does not prevent mouse scrapie. - Veterinary Microbiology 2007 Aug 31; 123(4): 367-76
AUSY - Nitschke,C.; Flechsig,E.; Dittmer,U.; Klein,M.A. - Cellular and humoral immune response against PrP in mice - TSE-Forum, 6. Kongress - Nationale TSE-Forschungsplattform, Greifswald 26.6.-28.6.2006, Poster: Therapie THE-04
AOXJ - Nitschke,C.; Flechsig,E.; Klein,M.A.; Dittmer,U. - Immune response in mice after immunisation against the prion protein - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - IV-28
AJPF - Prinz,M.; Montrasio,F.; Klein,M.A.; Schwarz,P.; Priller,J.; Odermatt,B.; Pfeffer,K.; Aguzzi,A. - Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells - Proceedings of the National Academy of Sciences of the United States of America 2002 Jan 22; 99(2): 919-24
AJVC - Raeber,A.J.; Montrasio,F.; Hegyi,I.; Frigg,R.; Klein,M.A.; Aguzzi,A.; Weissmann,C. - Studies on prion replication in spleen - Developmental Immunology 2001; 8(3-4): 291-304
AJVE - Raeber,A.J.; Klein,M.A.; Frigg,R.; Flechsig,E.; Aguzzi,A.; Weissmann,C. - PrP-dependent association of prions with splenic but not circulating lymphocytes of scrapie-infected mice - EMBO Journal 1999 May 17; 18(10): 2702-6
AJVF - Raeber,A.J.; Sailer,A.; Hegyi,I.; Klein,M.A.; Rülicke,T.; Fischer,M.; Brandner,S.; Aguzzi,A.; Weissmann,C. - Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication - Proceedings of the National Academy of Sciences of the United States of America 1999 Mar 30; 96(7): 3987-92
AJVG - Raeber,A.J.; Brandner,S.; Klein,M.A.; Benninger,Y.; Musahl,C.; Frigg,R.; Roeckl,C.; Fischer,M.B.; Weissmann,C.; Aguzzi,A. - Transgenic and knockout mice in research on prion diseases - Brain Pathology 1998 Oct; 8(4): 715-33
AJVH - Raeber,A.J.; Klein,M.A.; Frigg,R.; Brandner,S.; Blättler,T.; Aguzzi,A. - [Significance of prion protein in transmission of prions and in pathogenesis of spongiform encephalopathies] - Die Bedeutung des Prion-Proteins in der Ausbreitung von Prionen und in der Pathogenese der spongiformen Enzephalopathien - Wiener Medizinische Wochenschrift 1998; 148(4): 74-7
AOYC - Remer,K.A.; Flechsig,E.; Klein,M.A. - Up-take of prions by dendritic cells after exposure to mouse prions - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - PG-23
AKEH - Rossi,D.; Cozzio,A.; Flechsig,E.; Klein,M.A.; Rülicke,T.; Aguzzi,A.; Weissmann,C. - Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain - EMBO Journal 2001 Feb 15; 20(4): 694-702
ARKN - Thackray,A.M.; McKenzie,A.N.; Klein,M.A.; Lauder,A.; Bujdoso,R. - Accelerated prion disease in the absence of interleukin-10 - Journal of Virology 2004 Dec; 78(24): 13697-707
AOHQ - Thackray,A.M.; Klein,M.A.; Bujdoso,R. - Subclinical prion disease induced by oral inoculation - Journal of Virology 2003 Jul; 77(14): 7991-8
ALQG - Thackray,A.M.; Klein,M.A.; Aguzzi,A.; Bujdoso,R. - Chronic subclinical prion disease induced by low-dose inoculum - Journal of Virology 2002 Mar; 76(5): 2510-7
AMIB - Weissmann,C.; Raeber,A.J.; Montrasio,F.; Hegyi,I.; Frigg,R.; Klein,M.A.; Aguzzi,A. - Prions and the lymphoreticular system - Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 2001 Feb 28; 356(1406): 177-84
AYEU - Yun,S.W.; Kouznetsova,E.; Nitschke,C.; Heinitz,K.; Schliebs,R.; Gerlach,M.; Riederer,P.; Klein,M.A. - ß-Amyloid deposition and prion infection in adult primary brain cell long-term culture model - Biochemical and Biophysical Research Communications 2007 Aug 31; 360(3): 520-4
AUTC - Yun,S.W.; Ertmer,A.; Flechsig,E.; Gilch,S.; Riederer,P.; Gerlach,M.; Schätzl,H.M.; Klein,M.A. - Imatinib mesylate delays prion neuroinvasion by inhibiting prion propagation in the periphery - TSE-Forum, 6. Kongress - Nationale TSE-Forschungsplattform, Greifswald 26.6.-28.6.2006, Poster: Therapie THE-08
AVMB - Yun,S.W.; Gerlach,M.; Riederer,P.; Klein,M.A. - Oxidative stress in the brain at early preclinical stages of mouse scrapie - Experimental Neurology 2006 Sep; 201(1): 90-8
ATJY - Yun,S.W.; Gerlach,M.; Riederer,P.; Klein,M.A. - Oxidative stress is an early event in scrapie pathogenesis - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Diagnosis DIA-10
AGOK - Klein,R. - The politics of risk: the case of BSE. If we want less paternalism we must first educate ourselves. - British Medical Journal 2000 Nov 4; 321(7269): 1091-2
AGOL - Klein,R.; Dumble,L.J. - Transmission of Creutzfeldt-Jakob disease by blood transfusion - Lancet 1993 Mar 20; 341(8847): 768
ASCC - Klein,R.A. - Bonn - BSE a matter of perception in Germany - Lancet 1996; 348(9028): 675
ADQQ - Dumble,L.J.; Klein,R.D. - Creutzfeldt-Jakob legacy for Australian women treated with human pituitary gonadotropins - Lancet 1992 Oct 3; 340(8823): 847-8
ACPU - Choudhuri,R.; Cui,L.; Yong,C.; Bowyer,S.; Klein,R.M.; Welch,K.M.; Berman,N.E. - Cortical spreading depression and gene regulation: relevance to migraine. - Annals of Neurology 2002 Apr; 51(4): 499-506
AGOM - Klein,T.R.; Kirsch,D.; Kaufmann,R.; Riesner,D. - Prion rods contain small amounts of two host sphingolipids as revealed by thin-layer chromatography and mass spectrometry - Biological Chemistry 1998 Jun; 379(6): 655-66
ANCP - Bories,G.; Bridges,J.W.; Garrido Abellan,F.; Gibney,M.; Hardy,A.R.; James,P.T.; Jones,K.H.; Kemper,F.H.; Klein,W.; Knudsen,I.; Kroes,R.; Osterhaus,A.D.M.E.; Pascal,G.; Silano,V.; Vanbelle,M.; Wierup,M. - Scientific Steering Committee - Opinion of the Scientific Steering Committee on the scientific grounds of the Advice of 30 September 1999 of the French Food Safety Agency (the Agence Française de Sécurité Sanitaire des Aliments, AFSSA), to the French Government on the draft Decree amending the Decree of 28 October 1998 establishing specific measures applicable to certain products of bovine origin exported from the United Kingdom - European Commission, Health and Consumer Protection Directorate-General, Directorate B - Scientific Health Opinions, Unit B1 - Monitoring and dissemination of scientific opinions
AQEJ - Grathwohl,P.; Henschler,D.; Klein,W.; Miehlich,G.; Mühle,H.; Thoenes,H.W.; Walther,W.; Wilke,B.M. - Wege zum vorsorgenden Bodenschutz : fachliche Grundlagen und konzeptionelle Schritte für eine erweiterte Boden-Vorsorge - Wissenschaftlicher Beirat Bodenschutz beim BMU, publiziert in Bodenschutz und Altlasten Band 8, Erich Schmidt Verlag GmbH & Co., Berlin 2000
ANVS - Klein,W.; Herrchen,M.; Bachmann,G. - Potential stability of BSE-infectivity in soils. State of knowledge and research needs - Mögliche Langlebigkeit von TSE/BSE-Erregern in Böden. Sachstand und Konsequenzen für die Forschung - Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 2001 Apr; 44(4): 331-5