AXIK - Azadeh,K.S.; Carswell,C.; Quaratino,S.; Martins,S.; Properzi,F.; Mushens,R.; Clarke,A.R.; Jackson,G.S.; Anstee,D.; Collinge,J. - Immunotherapy- Active and Passive Immunisations in Prion Disease - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.155
AXIP - Banner,S.J.; Brown,D.; Thomson,V.; Shillinglaw,S.; Clarke,A.R.; Manson,J.; Gill,A.C. - Analysis of Murine CNS Proteomes from PRP0/0, PRPP101LL, PRPG3 and WT Mice - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.02
AWBJ - Banner,S.J.; Brown,D.; Thomson,V.; Clarke,A.R.; Manson,J.; Gill,A.C. - Analysis of murine CNS proteomes of PrP Knockout and WT mice - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions PA-04
AQHU - Beringue,V.; Vilette,D.; Mallinson,G.; Archer,F.; Kaisar,M.; Tayebi,M.; Jackson,G.S.; Clarke,A.R.; Laude,H.; Collinge,J.; Hawke,S. - PrPsc binding antibodies are potent inhibitors of prion replication in cell lines - The Journal of Biological Chemistry 2004 Sep 17; 279(38): 39671-6
ACQR - Clarke,A.R.; Jackson,G.S.; Collinge,J. - The molecular biology of prion propagation - Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 2001 Feb 28; 356(1406): 185-95
ACTY - Collinge,J.; Whittington,M.A.; Sidle,K.C.L.; Smith,C.J.; Palmer,M.S.; Clarke,A.R.; Jefferys,J.G.R. - Prion protein is necessary for normal synaptic function - Nature 1994 Jul 28; 370(6487): 295-7
AXLI - Edgeworth,J.A.; Weissman,C.; Clarke,A.R.; Jackson,G.S.; Collinge,J. - A Rapid, Quantitative Assay for the Presence of Steel-bound Prion Infectivity in Cultured Cells - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Epidemiology, Risk Assessment and Transmission P04.16
AFFD - Hasnain,S.S.; Murphy,L.M.; Strange,R.W.; Grossmann,J.G.; Clarke,A.R.; Jackson,G.S.; Collinge,J. - XAFS study of the high-affinity copper-binding site of human PrP(91-231) and its low-resolution structure in solution - Journal of Molecular Biology 2001 Aug 17; 311(3): 467-73
AUAW - Hosszu,L.L.P.; Wells,M.A.; Jackson,G.S.; Jones,S.; Batchelor,M.; Clarke,A.R.; Craven,C.J.; Waltho,J.P.; Collinge,J. - Definable equilibrium states in the folding of human prion protein - Biochemistry 2005 Dec 20; 44(50): 16649-57
AQKR - Hosszu,L.L.P.; Jackson,G.S.; Trevitt,C.R.; Jones,S.; Batchelor,M.; Bhelt,D.; Prodromidou,K.; Clarke,A.R.; Waltho,J.P.; Collinge,J. - The residue 129 polymorphism in human prion protein does not confer susceptibility to Creutzfeldt-Jakob disease by altering the structure or global stability of PrPc - The Journal of Biological Chemistry 2004 Jul 2; 279(27): 28515-21
AOUD - Hosszu,L.L.P.; Jackson,G.S.; Trevitt,C.R.; Jones,S.; Batchelor,M.; Prodromidou,K.; Clarke,A.R.; Waltho,J.P.; Collinge,J. - The residue 129 polymorphism in human prion protein does not confer susceptibility to CJD by altering the structure or stability of PrPc - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - BR-76 and BR-110
AFPG - Hosszu,L.L.P.; Baxter,N.J.; Jackson,G.S.; Power,A.; Clarke,A.R.; Waltho,J.P.; Craven,C.J.; Collinge,J. - Structural mobility of the human prion protein probed by backbone hydrogen exchange - Nature Structural Biology 1999 Aug; 6(8): 740-3
ARQJ - Jackson,G.S.; McKintosh,E.; Flechsig,E.; Prodromidou,K.; Hirsch,P.; Linehan,J.; Brandner,S.; Clarke,A.R.; Weissmann,C.; Collinge,J. - An enzyme-detergent method for effective prion decontamination of surgical steel - Journal of General Virology 2005 Mar; 86(3): 869-78
AFXK - Jackson,G.S.; Murray,I.; Hosszu,L.L.P.; Gibbs,N.; Waltho,J.P.; Clarke,A.R.; Collinge,J. - Location and properties of metal-binding sites on the human prion protein - Proceedings of the National Academy of Sciences of the United States of America 2001 Jul 17; 98(15): 8531-5
AFXM - Jackson,G.S.; Clarke,A.R. - Mammalian prion proteins - Current Opinion in Structural Biology 2000 Feb; 10(1): 69-74
AFXN - Jackson,G.S.; Hill,A.F.; Joseph,C.; Hosszu,L.; Power,A.; Waltho,J.P.; Clarke,A.R.; Collinge,J. - Multiple folding pathways for heterologously expressed human prion protein - Biochimica et Biophysica Acta 1999 Apr 12; 1431(1): 1-13
AFXO - Jackson,G.S.; Hosszu,L.L.P.; Power,A.; Hill,A.F.; Kenney,J.; Saibil,H.; Craven,C.J.; Waltho,J.P.; Clarke,A.R.; Collinge,J. - Reversible conversion of monomeric human prion protein between native and fibrilogenic conformations - Science 1999 Mar 19; 283(5409): 1935-7
ASGP - Johnston,A.R.; Black,C.J.; Fraser,J.R.; Manson,J.C.; Hope,J.; Clarke,A.R.; MacLeod,N. - Membrane-properties and synaptic plasticity in mouse ca1 hippocampal-neurons infected with me-7 scrapie or lacking the prion protein, studied in-vitro - Journal of Physiology 1996 Sep; 495: 15
AUBC - Jones,S.; Batchelor,M.; Bhelt,D.; Clarke,A.R.; Collinge,J.; Jackson,G.S. - Recombinant prion protein does not possess SOD-1 activity - Biochemical Journal 2005 Dec 1; 392(2): 309-12
ASKA - Khalili-Shirazi,A.; Quaratino,S.; Londei,M.; Summers,L.; Tayebi,M.; Clarke,A.R.; Hawke,S.H.; Jackson,G.S.; Collinge,J. - Protein conformation significantly influences immune responses to prion protein - Journal of Immunology 2005 Mar 15; 174(6): 3256-63
AXQM - Kristiansen,M.; Deriziotis,P.; Dimcheff,D.E.; Jackson,G.S.; Ovaa,H.; Naumann,H.; Clarke,A.R.; van Leeuwen,F.W.B.; Menendez-Benito,V.; Dantuma,N.P.; Portis,J.L.; Collinge,J.; Tabrizi,S.J. - Disease-associated Prion Protein Oligomers Inhibit the 26S Proteasome - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Oral Abstracts FC4.4
AWZN - Kristiansen,M.; Deriziotis,P.; Dimcheff,D.E.; Jackson,G.S.; Ovaa,H.; Naumann,H.; Clarke,A.R.; van Leeuwen,F.W.B.; Menendez-Benito,V.; Dantuma,N.P.; Portis,J.L.; Collinge,J.; Tabrizi,S.J. - Disease-associated prion protein oligomers inhibit the 26S proteasome - Molecular Cell 2007 Apr 27; 26(2): 175-88
AVBC - Lewis,P.A.; Tattum,M.H.; Jones,S.; Bhelt,D.; Batchelor,M.; Clarke,A.R.; Collinge,J.; Jackson,G.S. - Codon 129 polymorphism of the human prion protein influences the kinetics of amyloid formation - Journal of General Virology 2006 Aug; 87(8): 2443-9
AUIH - Lewis,P.A.; Properzi,F.; Prodromidou,K.; Clarke,A.R.; Collinge,J.; Jackson,G.S. - Removal of the glycosylphosphatidylinositol anchor from PrPsc by cathepsin D does not reduce prion infectivity - Biochemical Journal 2006 Apr 15; 395(2): 443-8
AHTY - Manson,J.C.; Clarke,A.R.; McBride,P.A.; McConnell,I.; Hope,J. - PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology - Neurodegeneration. A Journal for neurodegenerative Disorders, Neuroprotection, and Neuroregeneration 1994 Dec; 3(4): 331-40
AHTZ - Manson,J.C.; Clarke,A.R.; Hooper,M.L.; Aitchison,L.; McConnell,I.; Hope,J. - 129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal - Molecular Neurobiology 1994 Apr-Jun; 8(2-3): 121-7
AXSF - Marshall,A.S.; Manson,J.C.; Winton,D.J.; Clarke,A.R.; Tuzi,N.L. - Investigating the Effect of Conditional Expression of PrP Protein in the Intestine upon TSE Pathogenesis - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.23
AKYZ - Smith,C.J.; Drake,A.F.; Banfield,B.A.; Bloomberg,G.B.; Palmer,M.S.; Clarke,A.R.; Collinge,J. - Conformational properties of the prion octa-repeat and hydrophobic sequences - FEBS Letters 1997 Apr 1; 405(3): 378-84
AVVB - Stone,L.A.; Jackson,G.S.; Collinge,J.; Wadsworth,J.D.F.; Clarke,A.R. - Inhibition of proteinase K activity by copper(II) ions - Biochemistry 2007 Jan 9; 46(1): 245-52
AUJM - Tattum,M.H.; Cohen-Krausz,S.; Khalili-Shirazi,A.; Jackson,G.S.; Orlova,E.V.; Collinge,J.; Clarke,A.R.; Saibil,H.R. - Elongated oligomers assemble into mammalian PrP amyloid fibrils - Journal of Molecular Biology 2006 Mar 31; 357(3): 975-85
ARTZ - Tuzi,N.L.; Clarke,A.R.; Bradford,B.; Aitchison,L.; Thomson,V.; Manson,J.C. - Cre-loxP mediated control of PrP to study transmissible spongiform encephalopathy diseases - Genesis (New York, N.Y. : 2000) 2004 Sep; 40(1): 1-6
AMDO - Wadsworth,J.D.F.; Hill,A.F.; Joiner,S.; Jackson,G.S.; Clarke,A.R.; Collinge,J. - Strain-specific prion-protein conformation determined by metal ions - Nature Cell Biology 1999 May; 1(1): 55-9
AVPZ - Wells,M.A.; Jelinska,C.; Hosszu,L.L.P.; Craven,C.J.; Clarke,A.R.; Collinge,J.; Waltho,J.P.; Jackson,G.S. - Multiple forms of copper (II) co-ordination occur throughout the disordered N-terminal region of the prion protein at pH 7.4. - Biochemical Journal 2006 Dec 15; 400(3): 501-10
AVLY - Wells,M.A.; Jackson,G.S.; Jones,S.; Hosszu,L.L.P.; Craven,C.J.; Clarke,A.R.; Collinge,J.; Waltho,J.P. - A reassessment of copper(II) binding in the full-length prion protein - Biochemical Journal 2006 Nov 1; 399(3): 435-44
ACQS - Clarke,C.E.; Bamford,J.M.; House,A. - Dyskinesia in Creutzfeldt-Jakob disease precipitated by antidepressant therapy - Movement Disorders 1992; 7(1): 86-7
AHTB - Mallucci,G.R.; Campbell,T.A.; Dickinson,A.; Beck,J.A.; Holt,M.; Plant,G.; de Pauw,K.W.; Hakin,R.N.; Clarke,C.E.; Howell,S.; Davies-Jones,G.A.; Lawden,M.; Smith,C.M.; Ince,P.; Ironside,J.W.; Bridges,L.R.; Dean,A.; Weeks,I.; Collinge,J. - Inherited prion disease with an alanine to valine mutation at codon 117 in the prion protein gene - Brain: A Journal of Neurology 1999 Oct; 122(10): 1823-37
AKTH - Shaw,I.; Berry,C.; Lane,E.; Fitzmaurice,P.; Clarke,D.T.; Holden,A. - Studies on the putative interactions between the organophosphorus insecticide Phosmet and recombinant mouse PrP and its implication in the BSE epidemic - Veterinary Research Communications 2002 Jun; 26(4): 263-71
ALHQ - Symmons,M.F.; Buchanan,S.G.S.; Clarke,D.T.; Jones,G.; Gay,N.J. - X-ray diffraction and far-UV CD studies of filaments formed by a leucine-rich repeat peptide: structural similarity to the amyloid fibrils of prions and Alzheimer's disease beta-protein. - FEBS Letters 1997 Jul 28; 412(2): 397-403
ATLY - Clarke,J.; Cook,J.; Dobson,C.; Stumpf,R. - Evaluation of an automated tissue disruption system for use with a rapid TSE assay - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Diagnosis DIA-62
AXKZ - Dobson,C.; Navelkova,Z.; Buchbauerova,J.; Simmons,P.; Campos,S.; Garcia,D.; Cook,J.; Clarke,J.; Heath,N.; O'Brien,A.; Stumpf,R. - Evaluation of Plate Processing Instrumentation for Rapid TSE Assays - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Protein Misfolding P01.73
AWED - Dobson,C.; Heath,N.; Cook,J.; Stumpf,R.; O'Brien,A.; Clarke,J. - Use of probit analysis to compare rapid TSE assays - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions DIA-12
AWGO - Heath,N.; Dobson,C.; Cook,J.; Stumpf,R.; O'Brien,A.; Clarke,J. - Labour, space and resource implications of rapid assay automation - International Conference - Prion 2006: Strategies, advances and trends towards protection of society - 3.10.-6.10.2006, Torino, Italy, Lingotto Conference Centre - Poster sessions DIA-24
AOUT - Klass,M.; Hodges,S.; Lyons,V.; Sayers,R.; Clarke,J. - Testing for TSE: Mad cows, Scrapie Sheep and Wasted Deer and Elk - International Conference - Prion diseases: from basic research to intervention concepts - TSE-Forum, 08.10.-10.10.2003, Gasteig, München - Poster session - DG-18
ATLZ - Simmons,P.; Clarke,J.; Sawano,K.; Stumpf,R. - Performance and requirements for small and large scale labs using the Enfer version 2.0 assay - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Diagnosis DIA-63
ANJW - Scott,P.R.; Aldridge,B.M.; Clarke,M.; Will,R.G. - Cerebrospinal fluid studies in normal cows and cases of bovine spongiform encephalopathy - British Veterinary Journal 1990 Jan-Feb; 146(1): 88-90
AKQO - Scott,P.R.; Aldridge,B.M.; Clarke,M.; Will,R. - Bovine spongiform encephalopathy in a cow in the United Kingdom - Journal of the American Veterinary Medical Association 1989 Dec 15; 195(12): 1745-7
ANKO - Winter,M.H.; Aldridge,B.M.; Scott,P.R.; Clarke,M. - Occurrence of 14 cases of bovine spongiform encephalopathy in a closed dairy herd - British Veterinary Journal 1989 Mar-Apr; 145(2): 191-4
AYFQ - Clarke,M.B.; Forster,P.; Cook,T.M. - Airway management for tonsillectomy: a national survey of UK practice. - British Journal of Anaesthesia 2007 Sep; 99(3): 425-8
AAFP - Alper,T.; Haig,D.A.; Clarke,M.C. - The scrapie agent: evidence against its dependence for replication on intrinsic nucleic acid. - Journal of General Virology 1978 Dec; 41(3): 503-16
AAFT - Alper,T.; Cramp,W.A.; Haig,D.A.; Clarke,M.C. - Does the agent of scrapie replicate without nucleic acid? - Nature 1967 May 20; 214(90): 764-6
AAFU - Alper,T.; Haig,D.A.; Clarke,M.C. - The exceptionally small size of the scrapie agent - Biochemical and Biophysical Research Communications 1966 Feb 3; 22(3): 278-84
ABJL - Birkett,C.R.; Hennion,R.M.; Bembridge,D.A.; Clarke,M.C.; Chree,A.; Bruce,M.E.; Bostock,C.J. - Scrapie strains maintain biological phenotypes on propagation in a cell line in culture - EMBO Journal 2001 Jul 2; 20(13): 3351-8
ACQT - Clarke,M.C.; Kimberlin,R.H. - Pathogenesis of mouse scrapie: distribution of agent in the pulp and stroma of infected spleens. - Veterinary Microbiology 1984 Jul; 9(3): 215-25
ACQU - Clarke,M.C.; Millson,G.C. - The membrane location of scrapie infectivity - Journal of General Virology 1976 Jun; 31(3): 441-5
ACQV - Clarke,M.C.; Millson,G.C. - Infection of a cell line of mouse L fibroblasts with scrapie agent - Nature 1976 May 13; 261(5556): 144-5
ACQW - Clarke,M.C.; Haig,D.A. - The effect of homogenisation on the level of scrapie activity detected in cells from spleens of scrapie affected mice - Research in Veterinary Science 1976 Jan; 20(1): 106-7
ACQX - Clarke,M.C.; Haig,D.A. - An attempt to determine whether maternal transmission of scrapie occurs in mice - British Veterinary Journal 1971 Aug; 127(8): xxxii-xxxi
ACQY - Clarke,M.C.; Haig,D.A. - Multiplication of scrapie agent in mouse spleen - Research in Veterinary Science 1971 Mar; 12(2): 195-7
ACQZ - Clarke,M.C.; Haig,D.A. - Multiplication of scrapie agent in cell culture - Research in Veterinary Science 1970 Sep; 11(5): 500-1
ACRA - Clarke,M.C.; Haig,D.A. - Evidence for the multiplication of scrapie agent in cell culture - Nature 1970 Jan 3; 225(227): 100-1
ACRB - Clarke,M.C. - The antibody response of scrapie-affected mice to immunisation with sheep red blood cells - Research in Veterinary Science 1968 Nov; 9(6): 595-7
ACRC - Clarke,M.C.; Haig,D.A. - Presence of the transmissible agent of scrapie in the serum of affected mice and rats - The Veterinary Record 1967 Apr 22; 80(16): 504
ACRD - Clarke,M.C.; Haig,D.A. - Attempts to demonstrate neutralising antibodies in the sera of scrapie-affected animals - The Veterinary Record 1966 May 7; 78(19): 647-9
AUWL - Corp,C.R.; Clarke,M.C.; Kimberlin,R.H. - Factors in scrapie-infected mouse tissues that influence the metabolism of polyadenylated RNA in cell cultures - Veterinary Microbiology 1979; 4: 305-15
AFAB - Haig,D.A.; Clarke,M.C.; Millson,G.C. - Failure of fluorocarbon treatment to affect sensitivity of scrapie agent to ultraviolet light - Journal of Comparative Pathology 1977 Jan; 87(1): 103-7
AFAC - Haig,D.A.; Clarke,M.C. - Multiplication of the scrapie agent - Nature 1971 Nov 12; 234(5324): 106-7
ASMG - Haig,D.A.; Clarke,M.C.; Blum,E.; Alper,T. - Further studies on the inactivation of the scrapie agent by ultraviolet light - Journal of General Virology 1969 Oct; 5(3): 455-7
AFAD - Haig,D.A.; Clarke,M.C. - The effect of beta-propiolactone on the scrapie agent - Journal of General Virology 1968 Sep; 3(2): 281-3
ASMH - Haig,D.A.; Clarke,M.C. - Observations on the agent of scrapie - NINDB Monograph No.2, Slow, Latent and Temperate Virus Infections, Gajdusek, D.C., Gibbs, C.J.Jr., and Alpers,M., eds. Washington, U.S. Government Printing Office, pp.215-219, 1965
AHBM - Latarjet,R.; Muel,B.; Haig,D.A.; Clarke,M.C.; Alper,T. - Inactivation of the scrapie agent by near monochromatic ultraviolet light - Nature 1970 Sep 26; 227(265): 1341-3
AUXC - Lax,A.J.; Manning,E.J.; Clarke,M.C.; Kimberlin,R.H. - Mouse scrapie and polyadenylated RNA metabolism in L-cells - Veterinary Microbiology 1981; 6: 375-8
AJGY - Pattison,I.H.; Clarke,M.C.; Haig,D.A.; Jebbett,J.N. - Brain cell cultures from mice affected with scrapie or fed with cuprizone - Research in Veterinary Science 1971 Sep; 12(5): 478-80
AYAM - Clarke,P.S.; Will,R.G.; Ghani,A.C. - Is there the potential for an epidemic of variant Creutzfeldt-Jakob disease via blood transfusion in the UK? - Journal of the Royal Society Interface 2007 Aug 22; 4(15): 675-84
AVZT - Clarke,P.S.; Ghani,A.C. - A note on parameter estimation for variant Creutzfeldt-Jakob disease epidemic models - Statistics in Medicine 2007 Feb 10; 26(3): 546-52
AUEV - Clarke,P.S.; Ghani,A.C. - Projections of the future course of the primary vCJD epidemic in the UK: inclusion of subclinical infection and the possibility of wider genetic susceptibility. - Journal of the Royal Society Interface 2005 Mar 22; 2(2): 19-31
AVWM - Garske,T.; Ward,H.J.T.; Clarke,P.S.; Will,R.G.; Ghani,A.C. - Factors determining the potential for onward transmission of variant Creutzfeldt-Jakob disease via surgical instruments - Journal of the Royal Society Interface 2006 Dec 22; 3(11): 757-66
APOS - Clarke,R.A. - The BSE crisis - The Veterinary Record 1996 May 4; 138(18): 451-2