AGAT - Jin,T.; Gu,Y.; Zanusso,G.; Sy,M.; Kumar,A.; Cohen,M.L.; Gambetti,P.; Singh,N. - The chaperone protein BiP binds to a mutant prion protein and mediates its degradation by the proteasome - The Journal of Biological Chemistry 2000 Dec 8; 275(49): 38699-704
AVVL - Adamson,C.S.; Yao,Y.; Vasiljevic,S.; Sy,M.S.; Ren,J.; Jones,I.M. - Novel single chain antibodies to the prion protein identified by phage display - Virology 2007 Feb 5; 358(1): 166-77
ABSK - Brown,D.R.; Iordanova,I.K.; Wong,B.S.; Venien-Bryan,C.; Hafiz,F.; Glasssmith,L.L.; Sy,M.S.; Gambetti,P.; Jones,I.M.; Clive,C.; Haswell,S.J. - Functional and structural differences between the prion protein from two alleles prnp(a) and prnp(b) of mouse - European Journal of Biochemistry 2000 Apr; 267(8): 2452-9
ACEP - Capellari,S.; Parchi,P.; Russo,C.M.; Sanford,J.; Sy,M.S.; Gambetti,P.; Petersen,R.B. - Effect of the E200K mutation on prion protein metabolism. Comparative study of a cell model and human brain. - American Journal of Pathology 2000 Aug; 157(2): 613-22
ASOG - Cardinale,A.; Filesi,I.; Vetrugno,V.; Pocchiari,M.; Sy,M.S.; Biocca,S. - Trapping prion protein in the endoplasmic reticulum impairs PrPc maturation and prevents PrPsc accumulation - The Journal of Biological Chemistry 2005 Jan 7; 280(1): 685-94
AVQB - Chang,B.; Cheng,X.; Yin,S.; Pan,T.; Zhang,H.; Wong,P.; Kang,S.C.; Xiao,F.; Yan,H.; Li,C.; Wolfe,L.L.; Miller,M.W.; Wisniewski,T.; Greene,M.I.; Sy,M.S. - Test for detection of disease-associated prion aggregate in the blood of infected but asymptomatic animals - Clinical and Vaccine Immunology 2007 Jan; 14(1): 36-43
AOJK - Cui,T.; Daniels,M.; Wong,B.S.; Li,R.; Sy,M.S.; Sassoon,J.; Brown,D.R. - Mapping the functional domain of the prion protein - European Journal of Biochemistry 2003 Aug; 270(16): 3368-76
AROZ - Drisaldi,B.; Coomaraswamy,J.; Mastrangelo,P.; Strome,B.; Yang,J.; Watts,J.C.; Chishti,M.A.; Marvi,M.; Windl,O.; Ahrens,R.; Major,F.; Sy,M.S.; Kretzschmar,H.A.; Fraser,P.E.; Mount,H.T.J.; Westaway,D. - Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPc offset pro-apoptotic activity of the Doppel helix B/B' region. - The Journal of Biological Chemistry 2004 Dec 31; 279(53): 55443-54
AVQL - Franscini,N.; El Gedaily,A.; Matthey,U.; Franitza,S.; Sy,M.S.; Bürkle,A.; Groschup,M.H.; Braun,U.; Zahn,R. - Prion protein in milk - PLoS ONE 2006 Dec 20; 1: e71
AVWO - Goh,A.X.; Li,C.; Sy,M.S.; Wong,B.S. - Altered prion protein glycosylation in the aging mouse brain - Journal of Neurochemistry 2007 Feb; 100(3): 841-54
ASUW - Goni,F.; Knudsen,E.; Schreiber,F.; Scholtzova,H.; Pankiewicz,J.; Carp,R.I.; Meeker,H.C.; Rubenstein,R.; Brown,D.R.; Sy,M.S.; Chabalgoity,J.A.; Sigurdsson,E.M.; Wisniewski,T. - Mucosal vaccination delays or prevents prion infection via an oral route - Neuroscience 2005; 133(2): 413-21
AFIR - Herrmann,L.M.; Davis,W.C.; Knowles,D.P.; Wardrop,K.J.; Sy,M.S.; Gambetti,P.; O'Rourke,K.I. - Cellular prion protein is expressed on peripheral blood mononuclear cells but not platelets of normal and scrapie-infected sheep - Haematologica 2001 Feb; 86(2): 146-53
AQLG - Kang,S.C.; Brown,D.R.; Whiteman,M.; Li,R.; Pan,T.; Perry,G.; Wisniewski,T.; Sy,M.S.; Wong,B.S. - Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice - Journal of Pathology 2004 May; 203(1): 603-8
ANRD - Kang,S.C.; Li,R.; Wang,C.; Pan,T.; Liu,T.; Rubenstein,R.; Barnard,G.; Wong,B.S.; Sy,M.S. - Guanidine hydrochloride extraction and detection of prion proteins in mouse and hamster prion diseases by ELISA - Journal of Pathology 2003 Apr; 199(4): 534-41
ATDF - Kong,Q.; Huang,S.; Zou,W.Q.; Vanegas,D.; Wang,M.; Wu,D.; Yuan,J.; Zheng,M.; Bai,H.; Deng,H.; Chen,K.; Jenny,A.L.; O'Rourke,K.I.; Belay,E.D.; Schonberger,L.B.; Petersen,R.B.; Sy,M.S.; Chen,S.G.; Gambetti,P. - Chronic wasting disease of elk: transmissibility to humans examined by transgenic mouse models. - Journal of Neuroscience 2005 Aug 31; 25(35): 7944-9
AGZC - Laine,J.; Marc,M.E.; Sy,M.S.; Axelrad,H. - Cellular and subcellular morphological localization of normal prion protein in rodent cerebellum - European Journal of Neuroscience 2001 Jul; 14(1): 47-56
AXGQ - Li,C.; Wong,P.; Pan,T.; Xiao,F.; Yin,S.; Chang,B.; Kang,S.C.; Ironside,J.; Sy,M.S. - Normal cellular prion protein is a ligand of selectins: binding requires Le(X) but is inhibited by sLe(X). - Biochemical Journal 2007 Sep 1; 406(2): 333-41
ANRQ - Li,R.; Liu,T.; Yoshihiro,F.; Tary-Lehmann,M.; Obrenovich,M.; Kuekrek,H.; Kang,S.C.; Pan,T.; Wong,B.S.; Medof,M.E.; Sy,M.S. - On the same cell type GPI-anchored normal cellular prion and DAF protein exhibit different biological properties - Biochemical and Biophysical Research Communications 2003 Apr 4; 303(2): 446-51
AHGB - Li,R.; Liu,D.; Zanusso,G.; Liu,T.; Fayen,J.D.; Huang,J.H.; Petersen,R.B.; Gambetti,P.; Sy,M.S. - The expression and potential function of cellular prion protein in human lymphocytes - Cellular Immunology 2001 Jan 10; 207(1): 49-58
AHGC - Li,R.; Liu,T.; Wong,B.S.; Pan,T.; Morillas,M.; Swietnicki,W.; O'Rourke,K.I.; Gambetti,P.; Surewicz,W.K.; Sy,M.S. - Identification of an epitope in the C terminus of normal prion protein whose expression is modulated by binding events in the N terminus - Journal of Molecular Biology 2000 Aug 18; 301(3): 567-73
AHLZ - Liu,T.; Li,R.; Pan,T.; Liu,D.; Petersen,R.B.; Wong,B.S.; Gambetti,P.; Sy,M.S. - Intercellular transfer of the cellular prion protein - The Journal of Biological Chemistry 2002 Dec 6; 277(49): 47671-8
AHMA - Liu,T.; Zwingman,T.; Li,R.; Pan,T.; Wong,B.S.; Petersen,R.B.; Gambetti,P.; Herrup,K.; Sy,M.S. - Differential expression of cellular prion protein in mouse brain as detected with multiple anti-PrP monoclonal antibodies - Brain Research 2001 Mar 30; 896(1-2): 118-29
AHMB - Liu,T.; Li,R.; Wong,B.S.; Liu,D.; Pan,T.; Petersen,R.B.; Gambetti,P.; Sy,M.S. - Normal cellular prion protein is preferentially expressed on subpopulations of murine hemopoietic cells - Journal of Immunology 2001 Mar 15; 166(6): 3733-42
AHOH - Lu,K.; Wang,W.; Xie,Z.; Wong,B.S.; Li,R.; Petersen,R.B.; Sy,M.S.; Chen,S.G. - Expression and structural characterization of the recombinant human doppel protein - Biochemistry 2000 Nov 7; 39(44): 13575-83
AHTX - Manson,J.C.; Jamieson,E.; Baybutt,H.N.; Tuzi,N.L.; Barron,R.M.; McConnell,I.; Somerville,R.; Ironside,J.; Will,R.; Sy,M.S.; Melton,D.W.; Hope,J.; Bostock,C.J. - A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy - EMBO Journal 1999 Dec 1; 18(23): 6855-64
ATAI - Pan,T.; Chang,B.; Wong,P.; Li,C.; Li,R.; Kang,S.C.; Robinson,J.D.; Thompsett,A.R.; Tein,P.; Yin,S.; Barnard,G.; McConnell,I.; Brown,D.R.; Wisniewski,T.; Sy,M.S. - An aggregation-specific enzyme-linked immunosorbent assay: detection of conformational differences between recombinant PrP protein dimers and PrPsc aggregates. - Journal of Virology 2005 Oct; 79(19): 12355-64
ARSL - Pan,T.; Li,R.; Wong,B.S.; Kang,S.C.; Ironside,J.; Sy,M.S. - Novel antibody-lectin enzyme-linked immunosorbent assay that distinguishes prion proteins in sporadic and variant cases of Creutzfeldt-Jakob disease - Journal of Clinical Microbiology 2005 Mar; 43(3): 1118-26
ARSM - Pan,T.; Li,R.; Kang,S.C.; Pastore,M.; Wong,B.S.; Ironside,J.; Gambetti,P.; Sy,M.S. - Biochemical fingerprints of prion diseases: scrapie prion protein in human prion diseases that share prion genotype and type. - Journal of Neurochemistry 2005 Jan; 92(1): 132-42
ARMN - Pan,T.; Wong,P.; Chang,B.; Li,C.; Li,R.; Kang,S.C.; Wisniewski,T.; Sy,M.S. - Biochemical fingerprints of prion infection: accumulations of aberrant full-length and N-terminally truncated PrP species are common features in mouse prion disease. - Journal of Virology 2005 Jan; 79(2): 934-43
AQZB - Pan,T.; Li,R.; Kang,S.C.; Wong,B.S.; Wisniewski,T.; Sy,M.S. - Epitope scanning reveals gain and loss of strain specific antibody binding epitopes associated with the conversion of normal cellular prion to scrapie prion - Journal of Neurochemistry 2004 Sep; 90(5): 1205-17
AJEH - Pan,T.; Wong,B.S.; Liu,T.; Li,R.; Petersen,R.B.; Sy,M.S. - Cell-surface prion protein interacts with glycosaminoglycans - Biochemical Journal 2002 Nov 15; 368(1): 81-90
AJEI - Pan,T.; Li,R.; Wong,B.S.; Liu,T.; Gambetti,P.; Sy,M.S. - Heterogeneity of normal prion protein in two-dimensional immunoblot: presence of various glycosylated and truncated forms. - Journal of Neurochemistry 2002 Jun; 81(5): 1092-101
AJEJ - Pan,T.; Colucci,M.; Wong,B.S.; Li,R.; Liu,T.; Petersen,R.B.; Chen,S.; Gambetti,P.; Sy,M.S. - Novel differences between two human prion strains revealed by two-dimensional gel electrophoresis - The Journal of Biological Chemistry 2001 Oct 5; 276(40): 37284-8
AUYP - Pankiewicz,J.; Prelli,F.; Sy,M.S.; Kascsak,R.J.; Kascsak,R.B.; Spinner,D.S.; Carp,R.I.; Meeker,H.C.; Sadowski,M.; Wisniewski,T. - Clearance and prevention of prion infection in cell culture by anti-PrP antibodies - European Journal of Neuroscience 2006 May; 23(10): 2635-47
ANGA - Sigurdsson,E.M.; Sy,M.S.; Li,R.; Scholtzova,H.; Kascsak,R.J.; Kascsak,R.; Carp,R.I.; Meeker,H.C.; Frangione,B.; Wisniewski,T. - Anti-prion antibodies for prophylaxis following prion exposure in mice - Neuroscience Letters 2003 Jan 23; 336(3): 185-7
ALHO - Sy,M.S.; Gambetti,P.; Wong,B.S. - Human prion diseases - Medical Clinics of North America 2002 May; 86(3): 551-71, vi-vii
ALHP - Sy,M.S.; Gambetti,P. - Prion replication - once again blaming the dendritic cell - Nature Medicine 1999 Nov; 5(11): 1235-7
AXXR - Thackray,A.M.; Burke,D.F.; Fitzmaurice,T.M.; Hopkins,L.; Yu,S.; Sy,M.S.; Bujdoso,R. - Ease of Unwinding of Helix-2 Correlates with Stability of Allelic Variants of Ovine Prion Protein - International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Protein Misfolding P01.70
ALUS - Tuo,W.; Zhuang,D.; Knowles,D.P.; Cheevers,W.P.; Sy,M.S.; O'Rourke,K.I. - Prp-c and Prp-Sc at the fetal-maternal interface - The Journal of Biological Chemistry 2001 May 25; 276(21): 18229-34
ATER - Vetrugno,V.; Cardinale,A.; Filesi,I.; Mattei,S.; Sy,M.S.; Pocchiari,M.; Biocca,S. - KDEL-tagged anti-prion intrabodies impair PrP lysosomal degradation and inhibit scrapie infectivity - Biochemical and Biophysical Research Communications 2005 Dec 30; 338(4): 1791-7
ATIG - Vetrugno,V.; Cardinale,A.; Filesi,I.; Mattei,S.; Sy,M.S.; Pocchiari,M.; Biocca,S. - KDEL tagged anti-prion scFvs inhibit scrapie infection in vitro - International Conference - Prion 2005: Between fundamentals and society's needs - 19.10.-21.10.2005, Congress Center Düsseldorf - Poster Session: Cell Biology of PrPc and PrPsc CELL-38
ASRT - Wang,X.; Wang,F.; Sy,M.S.; Ma,J. - Calpain and other cytosolic proteases can contribute to the degradation of retro-translocated prion protein in the cytosol - The Journal of Biological Chemistry 2005 Jan 7; 280(1): 317-25
AOHZ - Wong,B.S.; Li,R.; Sassoon,J.; Kang,S.C.; Liu,T.; Pan,T.; Greenspan,N.S.; Wisniewski,T.; Brown,D.R.; Sy,M.S. - Mapping the antigenicity of copper-treated cellular prion protein with the scrapie isoform - Cellular and Molecular Life Science 2003 Jun; 60(6): 1224-34
AMRP - Wong,B.S.; Brown,D.R.; Pan,T.; Whiteman,M.; Liu,T.; Bu,X.; Li,R.; Gambetti,P.; Olesik,J.; Rubenstein,R.; Sy,M.S. - Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities - Journal of Neurochemistry 2001 Nov; 79(3): 689-98
AMRQ - Wong,B.S.; Brown,D.R.; Sy,M.S. - A Yin-Yang role for metals in prion disease - Panminerva Medica 2001 Dec; 43(4): 283-7
AMRR - Wong,B.S.; Chen,S.G.; Colucci,M.; Xie,Z.; Pan,T.; Liu,T.; Li,R.; Gambetti,P.; Sy,M.S.; Brown,D.R. - Aberrant metal binding by prion protein in human prion disease - Journal of Neurochemistry 2001 Sep; 78(6): 1400-8
AMRS - Wong,B.S.; Green,A.J.E.; Li,R.; Xie,Z.; Pan,T.; Liu,T.; Chen,S.G.; Gambetti,P.; Sy,M.S. - Absence of protease-resistant prion protein in the cerebrospinal fluid of Creutzfeldt-Jakob disease - Journal of Pathology 2001 May; 194(1): 9-14
AMRT - Wong,B.S.; Liu,T.; Paisley,D.; Li,R.; Pan,T.; Chen,S.G.; Perry,G.; Petersen,R.B.; Smith,M.A.; Melton,D.W.; Gambetti,P.; Brown,D.R.; Sy,M.S. - Induction of HO-1 and NOS in doppel-expressing mice devoid of PrP: implications for doppel function. - Molecular and Cellular Neurosciences 2001 Apr; 17(4): 768-75
AMRU - Wong,B.S.; Liu,T.; Li,R.; Pan,T.; Petersen,R.B.; Smith,M.A.; Gambetti,P.; Perry,G.; Manson,J.C.; Brown,D.R.; Sy,M.S. - Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein - Journal of Neurochemistry 2001 Jan; 76(2): 565-72
AMRV - Wong,B.S.; Venien-Bryan,C.; Williamson,R.A.; Burton,D.R.; Gambetti,P.; Sy,M.S.; Brown,D.R.; Jones,I.M. - Copper refolding of prion protein - Biochemical and Biophysical Research Communications 2000 Oct 5; 276(3): 1217-24
AMRW - Wong,B.S.; Pan,T.; Liu,T.; Li,R.; Petersen,R.B.; Jones,I.M.; Gambetti,P.; Brown,D.R.; Sy,M.S. - Prion disease: A loss of antioxidant function? - Biochemical and Biophysical Research Communications 2000 Aug 28; 275(2): 249-52
AMRX - Wong,B.S.; Pan,T.; Liu,T.; Li,R.; Gambetti,P.; Sy,M.S. - Differential contribution of superoxide dismutase activity by prion protein in vivo - Biochemical and Biophysical Research Communications 2000 Jun 24; 273(1): 136-9
AMRY - Wong,B.S.; Clive,C.; Haswell,S.J.; Williamson,R.A.; Burton,D.R.; Gambetti,P.; Sy,M.S.; Jones,I.M.; Brown,D.R. - Copper has differential effect on prion protein with polymorphism of position 129 - Biochemical and Biophysical Research Communications 2000 Mar 24; 269(3): 726-31
AXBG - Yin,S.; Pham,N.; Yu,S.; Li,C.; Wong,P.; Chang,B.; Kang,S.C.; Biasini,E.; Tien,P.; Harris,D.A.; Sy,M.S. - Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans - Proceedings of the National Academy of Sciences of the United States of America 2007 May 1; 104(18): 7546-51
AUPB - Yin,S.; Yu,S.; Li,C.; Wong,P.; Chang,B.; Xiao,F.; Kang,S.C.; Yan,H.; Xiao,G.; Grassi,J.; Tien,P.; Sy,M.S. - Prion proteins with insertion mutations have altered N-terminal conformation and increased ligand binding activity and are more susceptible to oxidative attack - The Journal of Biological Chemistry 2006 Apr 21; 281(16): 10698-705
AQTZ - Yin,S.M.; Sy,M.S.; Yang,H.Y.; Tien,P. - Interaction of Doppel with the full-length laminin receptor precursor protein - Archives of Biochemistry and Biophysics 2004 Aug 15; 428(2): 165-9
AQQO - Yin,S.M.; Sy,M.S.; Po,T. - An engineered PrPsc-like molecule from the chimera of mammalian prion protein and yeast Ure2p prion-inducing domain - Acta Biochimica et Biophysica Sinica 2004 Feb; 36(2): 128-32
AWVA - Yu,S.; Yin,S.; Li,C.; Wong,P.; Chang,B.; Xiao,F.; Kang,S.C.; Yan,H.; Xiao,G.; Tien,P.; Sy,M.S. - Aggregation of prion protein with insertion mutations is proportional to the number of inserts - Biochemical Journal 2007 Apr 15; 403(2): 343-51
ARLG - Yu,S.L.; Jin,L.; Sy,M.S.; Mei,F.H.; Kang,S.L.; Sun,G.H.; Tien,P.; Wang,F.S.; Xiao,G.F. - Polymorphisms of the PRNP gene in Chinese populations and the identification of a novel insertion mutation - European Journal of Human Genetics 2004 Oct; 12(10): 867-70
ASUM - Zaidi,S.I.A.; Richardson,S.L.; Capellari,S.; Song,L.; Smith,M.A.; Ghetti,B.; Sy,M.S.; Gambetti,P.; Petersen,R.B. - Characterization of the F198S prion protein mutation: enhanced glycosylation and defective refolding. - Journal of Alzheimer's Disease : JAD 2005 Apr; 7(2): 159-71; discussion 173-80
ANPJ - Zanusso,G.; Casalone,C.; Acutis,P.L.; Bozzetta,E.; Farinazzo,A.; Gelati,M.; Fiorini,M.; Forloni,G.; Sy,M.S.; Monaco,S.; Caramelli,M. - Molecular analysis of iatrogenic scrapie in Italy - Journal of General Virology 2003 Apr; 84(4): 1047-52
AMXU - Zanusso,G.; Liu,D.; Ferrari,S.; Hegyi,I.; Yin,X.; Aguzzi,A.; Hornemann,S.; Liemann,S.; Glockshuber,R.; Manson,J.C.; Brown,P.; Petersen,R.B.; Gambetti,P.; Sy,M.S. - Prion protein expression in different species: analysis with a panel of new mAbs. - Proceedings of the National Academy of Sciences of the United States of America 1998 Jul 21; 95(15): 8812-6
APNK - Zou,W.Q.; Capellari,S.; Parchi,P.; Sy,M.S.; Gambetti,P.; Chen,S.G. - Identification of novel proteinase K-resistant C-terminal fragments of PrP in Creutzfeldt-Jakob disease - The Journal of Biological Chemistry 2003 Oct 17; 278(42): 40429-36