NR AXJH
AU Bergmann,J.; Janetzky,B.; Preddie,E.
TI A Novel Model Advances the Understanding of TSE Pathology
QU International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Pathology and Pathogenesis P03.99
IA http://www.prion2007.com/pdf/Prion Book of Abstracts.pdf
PT Konferenz-Poster
AB All attempts at models to explain TSE fall short because there is insufficient understanding of the pathology of these diseases. Our discoveries of, and work with prionins, and implicating them in a re-interpretation of data published by others allowed us to design a new model which is simple to test and which provides new insights into the pathology of TSEs. Guided by this model we were able to identify novel, readily accessible, molecular targets which can be used for early diagnosis and against which therapeutic agents can be directed without concern for toxic effects in the subjects that are treated.
AD J. Bergmann, E. Preddie, Altegen, Inc., Germany; B. Janetzky, Carl-Gustav-Carus University of Dresden, Department of Neurology, Germany
SP englisch
PO Schottland