NR AXJF

AU Belay,E.; Weidenbach,K.; Pape,J.; Evdemon-Hogan,M.; Kazmierczak,J.; Curns,A.; Maddox,R.; Schonberger,L.

TI Monitoring the Potential Transmission of Chronic Wasting Disease to Humans

QU International Conference - Prion 2007 (26.-28.9.2007) Edinburgh International Conference Centre, Edinburgh, Scotland, UK - Book of Abstracts: Epidemiology, Risk Assessment and Transmission P04.99

IA http://www.prion2007.com/pdf/Prion Book of Abstracts.pdf

PT Konferenz-Poster

AB Chronic wasting disease (CWD) has been occurring in Colorado and Wyoming for decades and in Wisconsin for several years. Studies have shown the existence of a substantial species barrier for CWD transmission to humans. However, the transmission of bovine spongiform encephalopathy to humans indicates that this barrier may not be completely protective. In the United States, the Wyoming Department of Health (WDH), the Colorado Department of Public Health & Environment (CDPHE), and the Wisconsin Department of Health and Family Services established a follow-up study of hunters to monitor potential CWD transmission to humans. Identifiers from selected hunters are cross-checked with mortality data to determine their mortality status and causes of death. The WDH hunter study includes 966,339 records of licenses purchased during 1996-2005 whereas the CDPHE study contains about 3.9 million licenses purchased during 1995-2005. These licenses represent 292,873 and 919,684 individual hunters in Wyoming and Colorado, respectively. The median age of hunters was 42 years in Wyoming and 48 years in Colorado. About 19% of the hunters in Wyoming and 11% in Colorado purchased licenses to hunt in known CWD-endemic areas. Most of the other hunters had statewide licenses. A total of 194,206 records were cross-checked with mortality data in Wyoming and 470,046 records in Colorado; to date, 2 (including 1 identified by passive surveillance) and 4 hunters, respectively, died of CJD. In Wisconsin, 142 persons were identified as having consumed venison from CWD-positive deer harvested during 2003-2005. Hunter mortality studies are valuable to monitor possible CWD transmission to humans. CJD deaths unrelated to CWD are expected to be identified through cross-matching with mortality databases. Further epidemiologic and laboratory investigations are required to establish a causal association, if any, of the CJD deaths with CWD.

AD E. Belay, A. Curns, R. Maddox, L. Schonberger, Centers for Disease Control and Prevention, USA; K. Weidenbach, Wyoming Department of Health, USA; J. Pape, M. Evdemon-Hogan, Colorado Department of Public Health & Environment, USA; J. Kazmierczak, Wisconsin Department of Health and Family Services, USA

SP englisch

PO Schottland

EA pdf-Datei

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