NR AWXB

AU Perret,F.; Lazar,A.N.; Coleman,A.W.

TI Biochemistry of the para-sulfonato-calix[n]arenes

QU Chemical Communications (Cambridge, England) 2006 Jun 21(23): 2425-38

PT journal article; research support, non-u.s. gov't; review

AB The biochemistry of the para-sulfonato-calix[n]arenes has shown rapid development during the past ten years, the highly diverse biomedical applications of these molecules now include anti-viral, anti-thrombotic activities, enzyme blocking and protein complexation. The future is even more promising as para-sulfonato-calix[n]arenes have, now, been shown to have potential in the diagnosis of prion-based diseases. Their innocuous nature, as far as is known at present, may open up their future use in medications.

ZR 61

MH Acetylcholine/chemistry; Amino Acids/chemistry; *Anti-Infective Agents/chemical synthesis/chemistry/pharmacology; *Calixarenes/chemical synthesis/chemistry/pharmacology; Models, Molecular; Molecular Structure; Peptides/chemistry; Proteins/chemistry/drug effects; Steroids/chemistry; Structure-Activity Relationship

AD Institut de Biologie et Chimie des Proteines (IBCP UMR5086), CNRS, Universite Lyon 1, IFR128 BioSciences Lyon-Gerland, 7 passage du Vercors, F69367 Lyon, France.

SP englisch

PO England

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