NR AVXW
AU Ohnari,K.; Matsunaga,K.; Uozumi,T.; Tamagawa,A.; Hashimoto,T.; Tsuji,S.
TI Unilateral positive-negative myoclonus in Creutzfeldt-Jakob disease
QU Movement Disorders 2006 Nov; 21(11): 1963-6
PT case reports; journal article
AB We report a patient with Creutzfeldt-Jakob disease who presented asymmetric myoclonus. Positive-negative myoclonus was seen only in the right extremities in association with periodic synchronous discharges (PSDs) on the electroencephalogram, although pure positive myoclonus was rarely seen in the left extremities, independently in PSDs. The duration of the silent period recorded in the right-hand muscle produced by transcranial magnetic stimulation was much longer than that in the left-hand muscle or that in normal subjects. Brain MRI diffusion-weighted images showed signal hyperintensities in the putamen and cerebral cortex, including the motor cortex, predominantly on the left side.
MH Brain/pathology/physiopathology; Creutzfeldt-Jakob Syndrome/*complications/pathology; Electroencephalography/methods; Electromyography/methods; Evoked Potentials, Motor/physiology; *Functional Laterality; Humans; Magnetic Resonance Imaging/methods; Male; Middle Aged; Myoclonus/classification/*etiology/pathology
AD Department of Neurology, University of Occupational and Environmental Health, School of Medicine, Kitakyushu City, Japan.
SP englisch
PO USA