NR AVPF
AU Mouldi,S.; Le Rhun,E.; Gautier,S.; Devemy,M.; Destee,A.; Defebvre,L.
TI [Lithium-induced encephalopathy mimicking Creutzfeldt-Jakob disease]
OT Encephalopathie induite par le lithium mimant un tableau de maladie de Creutzfeldt-Jakob
QU Revue Neurologique 2006 Nov; 162(11): 1118-21
PT case reports; english abstract; journal article
AB INTRODUCTION: Creutzfeldt-Jakob disease (CJD) has a poor prognosis. Certain clinical presentations can be suggestive yet mimic a curable disease. OBSERVATION: In the present study, we report the case of a 67-year-old man with a one-month history of progressive dementia, with myoclonic jerks and cerebellar syndrome suggesting a diagnosis of Creutzfeldt-Jakob encephalopathy. He had been treated for 9 years with lithium for a bipolar disorder. The results of the different investigations and the favorable course after discontinuation of lithium were in favor of the diagnosis of drug-induced Creutzfeldt-Jakob syndrome. CONCLUSION: This case illustrates the importance for researching a curable etiology in presence of clinical features suggesting a CJD.
MH Aged; Antimanic Agents/*adverse effects; Brain Diseases/*diagnosis/*drug therapy; Creutzfeldt-Jakob Syndrome/*diagnosis; Diagnosis, Differential; Electroencephalography; Female; Humans; Lithium Chloride/*adverse effects; Male; Middle Aged
AD Service de Neurologie et Pathologie du Mouvement, EA 2683, Hopital Roger Salengro, rue du Professeur Emile Laine, CHRU, 59037 Lille Cedex.
SP französisch
PO Frankreich