NR AUYA
AU Avanzino,L.; Marinelli,L.; Buccolieri,A.; Trompetto,C.; Abbruzzese,G.
TI Creutzfeldt-Jakob disease presenting as corticobasal degeneration: a neurophysiological study.
QU Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2006 Jun; 27(2): 118-21
PT case reports; journal article
AB Creutzfeldt-Jakob disease (CJD) can occasionally present with a clinical picture resembling a corticobasal degeneration (CBD). Transcallosal inhibition, as tested by focal transcranial magnetic stimulation, is frequently absent or highly disrupted in CBD patients. We report a case of CJD presenting at the beginning of the disease as a CBD in which the ipsilateral silent period (iSP) was present and well detectable. This brief report shows that study of the iSP may be a useful diagnostic tool in order to differentiate CBD from syndromes presenting with similar clinical features.
MH Creutzfeldt-Jakob Syndrome/*diagnosis; Diagnosis, Differential; Fatal Outcome; Female; Humans; Middle Aged; Neurodegenerative Diseases/*diagnosis; *Transcranial Magnetic Stimulation
AD Department of Neurosciences, Ophthalmology & Genetics, University of Genoa, Via de Toni 5, I-16132, Genoa, Italy.
SP englisch
PO Italien