NR AQMJ
AU Madhavaiah,C.; Verma,S.
TI Self-aggregation of reverse bis peptide conjugate derived from the unstructured region of the prion protein
QU Chemical Communications (Cambridge, England) 2004 Mar 21(6): 638-9
PT journal article
AB A novel bis scaffold containing a pentapeptide PHGGG, derived from the prion octarepeat, forms fibrils of nanometric dimensions, thus indicating that certain segments in the unstructured region of the prion protein may facilitate an initial fibrillation event.
MH Molecular Structure; Peptides/*chemical synthesis/*chemistry; Prions/*chemistry; Research Support, Non-U.S. Gov't
AD Department of Chemistry, Indian Institute of Technology-Kanpur, Kanpur-208016, UP, India.
SP englisch
PO England