NR ANUU
AU Madar,R.; Maslenova,D.; Ranostajova,K.; Straka,S.; Baska,T.
TI Analysis of unusual accumulation of Creutzfeldt-Jakob disease cases in Orava and Liptov regions (northern Slovak focus) 1983-2000
QU Central European Journal of Public Health 2003 Mar; 11(1): 19-22
PT journal article
AB While familial cases of Creutzfeldt-Jakob disease are extremely rare all over the world, 3 familial clusters were observed between 1983-2000 in a relatively small area situated in the North of Slovakia. Prevalence of CJD in this area exceeded the overall prevalence in Slovakia more than 8 times. The majority of CJD patients admitted consuming sheep brain. Most patients lived in small secluded villages with rather common familial intermarriage. CJD affected both sexes equally. All patients were prior to the disease mentally normal individuals. Shortly after the onset of CJD their mental status deteriorated remarkably with an average survival rate of 3.6 months.
MH Adolescent; Adult; Age Distribution; Aged; Animal; Cluster Analysis; Comparative Study; Consanguinity; Creutzfeldt-Jakob Syndrome/*epidemiology/genetics; Family Health; Female; Human; Male; Meat Products/adverse effects; Middle Age; Prevalence; Sex Distribution; Sheep; Slovakia/epidemiology
AD Institute of Epidemiology, Jessenius Faculty of Medicine, Comenius University, Sklabinska 26, Martin, 037 53 Slovakia. MADAR@jfmed.uniba.sk
SP englisch
PO Tschechische Republik