NR ANRS
AU Machida,K.
TI [Bacillus anthracis, prions, Coxiella burnetii]
QU Rinsho Byori. Japanese Journal of Clinical Pathology 2002 Nov; Suppl 123: 79-87
PT journal article
AB The detection kits for Bacillus anthracis, an isoform of host prion and Coxiella burnetii, using genetic technology are still not generalized. For B. anthracis target genes for detection would be genes of toxins. Although it is difficult to detect prions related to prion diseases before death, some mutants of prion gene in leukocytes and 14-3-3 proteins in cerebrospinal fluid are detectable in living patients suffering from Creutzfeldt-Jakob disease. The gene of superoxide dismutase in Coxiella burnetii is a useful target for detecting this Rickettsiae.
AD Department of Laboratory Medicine, Jikei University School of Medicine.
SP japanisch
PO Japan