NR ANAF

AU Zimmermann,K.; Gibrat,J.F.

TI In unison: regularization of protein secondary structure predictions that makes use of multiple sequence alignments.

QU Protein Engineering 1998 Oct; 11(10): 861-5

PT journal article

AB We present a method whose purpose is to post-process the fuzzy results of secondary structure prediction methods that use multiple sequence alignments, in order to obtain 'realistic' secondary structures, i.e., secondary structure elements whose length is greater than or equal to some predefined minimum length. This regularization helps with interpretation of the secondary structure prediction.

MH Algorithms; Amino Acid Sequence; Animal; Consensus Sequence; Hamsters; Molecular Sequence Data; Prions/chemistry; *Protein Structure, Secondary; Sensitivity and Specificity; *Sequence Alignment; Software

AD Unite de Bio-Informatique, INRA, Jouy-en-Josas, France.

SP englisch

PO England

EA pdf-Datei

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