NR AMUH
AU Yamada,S.; Aiba,T.; Endo,Y.; Hara,M.; Kitamoto,T.; Tateishi,J.
TI Creutzfeldt-Jakob disease transmitted by a cadaveric dura mater graft
QU Neurosurgery 1994 Apr; 34(4): 740-3; discussion 743-4
PT journal article; review; review of reported cases
AB We report a case of Creutzfeldt-Jakob disease developing in a 31-year-old woman 56 months after she received a cadaveric dura mater graft after the removal of a giant pituitary adenoma. Creutzfeldt-Jakob disease was confirmed by a brain autopsy and the existence of an abnormal isoform of prion protein, verified by both immunohistochemical and Western blot analysis. Moreover, prion protein gene analysis was shown in this case to possess a wild-type genotype. The characteristics of Creutzfeldt-Jakob disease after a cadaveric dura mater graft are reviewed and discussed.
IN Bei einer 31 Jahre alten Frau entwickelte sich 56 Monate nach Implatation einer harten Hirnhaut die Creutzfeldt-Jakob-Krankheit.
ZR 43
MH Adenoma/pathology/*surgery; Adult; Blotting, Western; Brain/pathology; Case Report; Collagen/*adverse effects; *Craniotomy; Creutzfeldt-Jakob Syndrome/diagnosis/genetics/pathology/*transmission; Fatal Outcome; Female; Follow-Up Studies; Growth Hormone/*secretion; Human; Magnetic Resonance Imaging; Neurologic Examination; Pituitary Neoplasms/pathology/*surgery; Postoperative Complications/*diagnosis/pathology; Prions/genetics
AD Department of Neurosurgery, Toranomon Hospital, Tokyo, Japan.
SP englisch
PO USA