NR AMTW
AU Yagishita,S.; Iwabuchi,K.; Amano,N.; Yokoi,S.
TI Further observation of Japanese Creutzfeldt-Jakob disease with widespread amyloid plaques
QU Journal of Neurology. Zeitschrift für Neurologie 1989 Mar; 236(3): 145-8
PT journal article
AB An autopsy case of Creutzfeldt-Jakob disease with widespread amyloid plaques is reported. A 45-year-old Japanese man, whose father had died of a similar disease, had a 5-year illness characterized by progressive cerebellar signs. Mental changes and brain-stem signs developed in the late stage. Myoclonus frequently occurred. Akinetic mutism ensued. The autopsy revealed spongiform encephalopathy with widespread amyloid plaques and extensive degeneration of the white matter. This disease, Western Gerstmann-Sträussler-Scheinker disease and panencephalopathic type of Creutzfeldt-Jakob disease are discussed.
MH Amyloid/*analysis; Amyloid beta-Protein; Brain/metabolism/*pathology; Case Report; Creutzfeldt-Jakob Syndrome/metabolism/*pathology; Human; Japan; Male; Middle Age
AD Division of Pathology, Kanagawa Rehabilitation Centre, Japan.
SP englisch
PO Westdeutschland