NR AMTM
AU Wyatt,J.M.; Pearson,G.R.; Smerdon,T.N.; Gruffydd-Jones,T.J.; Wells,G.A.H.; Wilesmith,J.W.
TI Naturally occurring scrapie-like spongiform encephalopathy in five domestic cats
QU The Veterinary Record 1991 Sep 14; 129(11): 233-6
KI Vet Rec. 1991 Oct 5;129(14):320. PMID: 1801815
PT journal article
AB Naturally occurring transmissible spongiform encephalopathies have been recognised in sheep, man, mink, captive deer and cattle. Recently a similar disease was reported in a domestic cat. This paper describes the clinical and pathological findings in five cats with similar signs, including further observations on the original case. All the cats had a progressive, neurological disease involving locomotor disturbances, abnormal behaviour and, in most cases, altered sensory responses. Histopathological examination of the central nervous system revealed changes pathognomonic of the scrapie-like encephalopathies, including widespread vacuolation of the grey matter neuropil, vacuolation of neuronal perikarya and an astrocytic reaction.
IN Die Autoren beschreiben die klinischen und pathologischen Befunde von 5 Hauskatzen, bei denen in England TSE diagnostiziert wurden. Der Bericht erwähnt noch keine Übertragungsversuche, sodass eine Erregerstammtypisierung noch nicht möglich ist. Die Quelle könnte BSE oder Scrapie gewesen sein.
MH Animal; Animals, Domestic/microbiology; Brain Diseases/diagnosis/pathology/*veterinary; Case Report; Cat Diseases/diagnosis/*pathology; Cats; Cattle; Diagnosis, Differential; Female; Male; Scrapie/*diagnosis; Slow Virus Diseases/diagnosis/pathology/*veterinary; Support, Non-U.S. Gov't
AD Department of Pathology and Microbiology, University of Bristol, School of Veterinary Science, Langford.
SP englisch
PO England