NR AMPS
AU Willoughby,K.; Kelly,D.F.; Lyon,D.G.; Wells,G.A.H.
TI Spongiform encephalopathy in a captive puma (Felis concolor)
QU The Veterinary Record 1992 Nov 7; 131(19): 431-4
PT journal article
AB A captive adult puma developed ataxia, a hypermetric gait and whole body tremor. The signs progressed over a period of six weeks. Histopathological examination following euthanasia demonstrated spongiform encephalopathy, gliosis and mild non-suppurative meningoencephalitis. Immunostaining with a polyclonal antiserum revealed prion protein (PrP) associated with these changes in sections of cervical spinal cord and medulla. This is the first confirmed case of a scrapie-like spongiform encephalopathy described in a non-domestic cat in the United Kingdom.
IN Ein in England in Gefangenschaft lebender Puma (8.3.86-16.5.81 [AGMP]) starb an einer spongiformen Encephalopathie. Die TSE-Diagnose wurde histopathologisch und immunhistologisch bestätigt.
MH Animal; Animals, Zoo; Brain/pathology; Brain Diseases/microbiology/pathology/*veterinary; *Carnivora; Case Report; Female; Immunohistochemistry; Medulla Oblongata/microbiology; Prions/isolation & purification; Slow Virus Diseases/microbiology/pathology/*veterinary; Spinal Cord/microbiology/pathology; Support, Non-U.S. Gov't
AD Department of Veterinary Clinical Science, University of Liverpool.
SP englisch
PO England