NR AMNJ
AU Wilkins,D.E.; Hallett,M.; Berardelli,A.; Walshe,T.; Alvarez,N.
TI Physiologic analysis of the myoclonus of Alzheimer's disease
QU Neurology 1984 Jul; 34(7): 898-903
PT journal article
AB Ten patients with clinically diagnosed Alzheimer's disease, including three cases of trisomy 21 (Down's syndrome), developed a chronic myoclonic disorder. The technique of jerk-locked averaging of EEG activity was used to analyze the myoclonus. Seven subjects demonstrated a focal, contralateral central, negative cerebral potential antecedent to the myoclonic jerks. This EEG event differs from that previously reported to be associated with the myoclonus of subacute spongiform encephalopathy (Creutzfeldt-Jakob disease).
MH Aged; Alzheimer Disease/*physiopathology; Down Syndrome/complications/physiopathology; Electroencephalography; Female; Human; Male; Middle Age; Myoclonus/complications/*physiopathology
SP englisch
PO USA