NR AMJN
AU Wells,G.A.H.; McGill,I.S.
TI Recently described scrapie-like encephalopathies of animals: case definitions
QU Research in Veterinary Science 1992 Jul; 53(1): 1-10
PT journal article; review; review, tutorial
AB Since 1986, naturally occurring scrapie-like encephalopathies have been described in the United Kingdom in domestic cattle, in five species of captive exotic bovids and in domestic cats. The disease in domestic cattle, bovine spongiform encephalopathy, has been characterised by all currently available diagnostic criteria as a transmissible spongiform encephalopathy or 'prion' disease, and has been shown to have a dietary origin. The pathology in the other species is also entirely consistent with the scrapie-like diseases. The contemporaneous occurrence in the UK of such disease in these species suggests a close epidemiological association. The diagnostic criteria of the scrapie-like encephalopathies of animals are reviewed in the light of experience with the recent extension of their natural host range.
IN Zeitlich und räumlich assoziiert mit der britischen BSE-Epidemie traten im Vereinigten Königreich BSE-ähnliche Prion-Krankheiten bei einem Nyala-Buschbock (Tragelaphus angasi) [ASYI,AGMP], einem Spießbock (Oryx gazella) [ASYI,AGMP], einer Elenantilope (Taurotragus oryx) [AEBJ,AGMP], einer arabischen oder weißen Oryx-Antilope (Oryx leucoryx) und einer großen Kudu-Waldantilope (Tragelaphus strepsiceros) [AGMT,AGMP] sowie bei Katzen auf. Anders als bei BSE fand man bei den betroffenen Katzen starke Schädigungen in der Hirnrinde und basalen Hirnkernen.
ZR 86
MH Animal; Prion Diseases/classification/diagnosis/pathology/*veterinary
AD Pathology Department, Central Veterinary Laboratory, Weybridge, Surrey.
SP englisch
PO England
OR Prion-Krankheiten 8