NR AMFF

AU Wang,Q.; Lu,B.X.

TI Single photon emission computerized tomography of spongiform leukoencephalopathy heroin addicts: analysis of 10 cases.

QU Di Yi Jun Yi Da Xue Xue Bao - Academic Journal of the First Medical College of PLA 2002 Jul; 22(7): 659-60

PT journal article

AB OBJECTIVE: To investigate the changes in cerebral circulation in heroin addicts with pongiform leukoencephalopathy. METHODS: Single photon emission computerized tomography (SPECT) was performed in 10 such patients. RESULTS: Regional cerebral blood flow (rCBF) in the involved white matter of bilateral cerebral and cerebellar hemispheres was obviously reduced. rCBF of temporal lobes, parietal lobes, cerebellar hemispheres and basal ganglion were reduced in varying degrees. CONCLUSION: As demonstrated by the result of SPECT, rCBF in the white matter of bilateral cerebral and cerebellar hemispheres was reduced with partial involvement of the gray matter of heroin addicts with spongiform leukoencephalopathy.

MH Adult; Cerebral Cortex/*blood supply; Creutzfeldt-Jakob Syndrome/physiopathology; Heroin Dependence/*physiopathology; Human; Leukoencephalopathy, Progressive Multifocal/*physiopathology; Male; Regional Blood Flow; Tomography, Emission-Computed, Single-Photon/*methods

AD Department of Neurology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.

SP englisch

PO China

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