NR ALQP
AU Thiel,H.J.; Erb,C.; Heckmann,J.; Lang,C.J.G.; Neundörfer,B.
TI [Manifestation of Creutzfeldt-Jakob disease 30 years after corneal transplantation]
OT Manifestation einer Creutzfeldt-Jakobschen Erkrankung 30 Jahre nach einer Hornhauttransplantation
QU Klinische Monatsblätter für Augenheilkunde 2000 Nov; 217(5): 303-7
PT journal article
AB BACKGROUND: Creutzfeldt-Jakob disease, currently viewed as one of the prionic diseases, occurs in by far the majority of cases sporadically, sometimes in families, and in rare instances as a transmissible disease with every conceivable interval of latency. HISTORY AND SIGNS: This report of a 45-year-old female concerns a spongiform encephalopathy which appeared almost 30 years after penetrating keratoplasty. The corneal material came from a 63-year-old donor with Creutzfeldt-Jakob disease; the keratoplasty was performed at a time when the transmissibility of certain diseases was still unknown. CONCLUSION: The risk of transmission of the disease is very low but cannot be ruled out.
MH Case Report; Creutzfeldt-Jakob Syndrome/*diagnosis/transmission; English Abstract; Fatal Outcome; Female; Human; *Keratoplasty, Penetrating; Middle Age; Neurologic Examination; Postoperative Complications/*diagnosis; Risk Factors; Tissue Donors
AD Universitäts-Augenklinik Tübingen, Abt. Augenheilkunde I, Allgemeine Augenheilkunde mit Poliklinik, Schleichstrasse 12, 72076 Tübingen.
SP deutsch
PO Deutschland