NR AJNO
AU Poon,T.P.; Tchertkoff,V.; de Jesus,M.; Lahiri,A.; Lansen,T.
TI Giant collagen plaques in Creutzfeldt-Jakob disease. Report of two cases with ultrastructural studies.
QU Acta Neuropathologica 1993; 85(3): 323-6
PT journal article
AB We report two cases of Creutzfeldt-Jakob disease with clusters of giant collagen fibers. To our knowledge, these abnormally large collagen fibers have never been described in patients with degenerative diseases of the central nervous system. The significance of the formation of such plaque-like large collagen fibers has as yet not been elucidated. It is felt that these represent a product of the degenerative process.
MH Adult; Brain/*ultrastructure; Case Report; Collagen/*metabolism; Creutzfeldt-Jakob Syndrome/*metabolism/pathology; Female; Human; Male; Microscopy, Electron; Middle Age
AD Department of Pathology, New York Medical College, Metropolitan Hospital Center, NY 10029.
SP englisch
PO Deutschland