NR AJGK

AU Patterson,W.J.; Painter,M.J.

TI Bovine spongiform encephalopathy and new variant Creutzfeldt-Jakob disease: an overview.

QU Communicable Disease and Public Health 1999 Jan; 2(1): 5-13

PT journal article; review; review, tutorial

AB About 10 years after bovine spongiform encephalopathy (BSE) appeared in British cattle, a new variant of Creutzfeldt-Jakob disease (nv-CJD) was described in the United Kingdom. This new disease is distinguishable from classical CJD in its aetiology, epidemiology, clinical profile, and neuropathology. The emergence of nv-CJD raised fears of a causal relationship between BSE and nv-CJD and of a human epidemic of indeterminate size. This paper reviews our knowledge of this group of diseases, and examines recent scientific evidence, which indicates that BSE is indeed the source of nv-CJD, and discusses the public health implications.

ZR 120

MH Animal; Cattle; Creutzfeldt-Jakob Syndrome/*epidemiology/*etiology; *Disease Outbreaks; Encephalopathy, Bovine Spongiform/*epidemiology/*transmission; Great Britain/epidemiology; Human; Public Health

AD North Yorkshire Health Authority, York. will.patterson@nyorks-ha.northy.nhs.uk

SP englisch

PO England

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