NR AJAA
AU Ojeda,V.J.; Mastaglia,F.L.; Kakulas,B.A.
TI Causes of organic dementia: a necropsy survey of 60 cases.
QU Medical Journal of Australia 1986 Jul 21; 145(2): 69-71
PT journal article
AB The neuropathological findings in all demented patients who were necropsied at the Sir Charles Gairdner Hospital during a 10-year period were reviewed. Of a total of 60 cases, 44 (73.3%) had the typical changes of Alzheimer's disease, while a variety of other conditions accounted for the remaining 16 cases - neoplasms (four patients); lacunar disease (four patients); viral infections (three patients: herpes simplex in two and Creutzfeldt-Jakob disease in one); non-specific brain atrophy (two patients); and single cases of Huntington's chorea, subdural haematomas and methotrexate-induced leucoencephalopathy. Associated cerebral pathologies were found in 17 (38.6%) of the cases of Alzheimer's disease and included vascular lesions (eight cases), subdural haematomas (six cases) and Wernicke's encephalopathy (two cases).
MH Aged; Alzheimer Disease/pathology; Brain/pathology; Cerebral Cortex/pathology; Cerebral Infarction/pathology; Delirium, Dementia, Amnestic, Cognitive Disorders/*etiology; Dementia/*etiology/pathology; Female; Hematoma, Subdural/pathology; Human; Male; Middle Age; Organ Weight; Temporal Lobe/pathology
SP englisch
PO Australien