NR AHPK
AU Luo,Y.; Huang,K.
TI Spongy degeneration of the CNS in infancy
QU Archives of Neurology 1984 Feb; 41(2): 164-70
PT journal article
AB We studied six cases of spongy degeneration of the CNS in infancy among Chinese. The main clinical features were cyclical vomiting and wailing, blindness, megalocephaly, convulsions, lethargy, and coma. Chief findings from light microscopic studies were spongiform change, moderate outfall of neurons, and marked astrocytosis, with formation of Alzheimer's cells type 2. Demyelination was only slight, if present. Electron microscopic studies revealed membrane-bound vacuoles, often containing membranous fragments or blisters and electron-dense granules.
MH Brain/ultrastructure; Brain Diseases/*pathology; Case Report; Cerebral Cortex/pathology/ultrastructure; Creutzfeldt-Jakob Syndrome/pathology; Female; Human; Infant; Male; Mongoloid Race
SP englisch
PO USA