NR AHNJ
AU Lopez,O.L.; Larumbe,M.R.; Becker,J.T.; Martinez-Lage,J.M.; Boller,F.
TI [Difficulties in differential diagnosis of long-term Creutzfeldt-Jakob disease]
OT Dificultades en el diagnostico diferencial de la enfermedad de Creutzfeldt-Jakob de curso prolongado
QU Neurologia 1995 Jan; 10(1): 37-40
KI Neurologia. 1995 May;10(5):213-4. PMID: 7619542
ER Neurologia 1995 Apr;10(4):177
PT journal article
AB Creutzfeldt-Jakob disease (CJD) is characterized by a rapidly progressive dementia that often leads to death within a few months of onset. However, some cases evolve over a much longer period of time and have a clinical picture that is difficult to distinguish from other progressive dementias that occur in the adult, especially Alzheimer's disease (AD). We examine the clinical features of 3 patients with pathologically confirmed CJD whose course was slow (4-5 years) and who were initially diagnosed as having AD. Only two of them had shown signs of CJD in the terminal stages. In this study we examine the clinical characteristics of these patients, and discuss of differentiating CJD from other entities, especially from AD.
MH Aged; Alzheimer Disease/diagnosis/physiopathology; Brain/physiopathology; Case Report; Creutzfeldt-Jakob Syndrome/complications/*diagnosis/physiopathology; Diagnosis, Differential; English Abstract; Human; Kuru/etiology; Male; Purkinje Cells/ultrastructure; Support, U.S. Gov't, P.H.S.
AD Departamento de Neurologia, University of Pittsburgh Medical Center, Pennsylvania.
SP spanisch
PO Spanien