NR AHIZ
AU Liberski,P.P.; Papierz,W.; Alwasiak,J.
TI Creutzfeldt-Jakob disease with plaques and paired helical filaments
QU Acta Neurologica Scandinavica 1987 Dec; 76(6): 428-32
PT journal article
AB A 32-year-old man with rapidly progressive dementia, pyramidal signs, myoclonic jerks and dystonic movements died following brain biopsy. neuropathological examination revealed minimal neuronal loss accompanied by mild spongiform change and astrocytic reaction. Numerous plaques and neurofibrillary tangles composed of paired helical filaments dominated the ultrastructural picture. This patient had features of both Creutzfeldt-Jakob disease and Alzheimer's disease, providing additional support for the existence of an overlap between these disorders.
MH Adult; Alzheimer Disease/pathology/transmission; Animal; Case Report; Creutzfeldt-Jakob Syndrome/*pathology/transmission; Hamsters; Human; Male; Mesocricetus; Neurofibrils/*ultrastructure; Saimiri; Support, Non-U.S. Gov't
AD Department of Neurology, Medical Academy, Lodz, Poland.
SP englisch
PO Dänemark