NR AGQN
AU Kolomiets,N.D.; Mil'kamanovich,E.K.; Kolomiets,A.G.; Luchko,V.P.; Krishchanovich,V.V.; Protas,I.I.
TI [Intravital laboratory diagnosis of human subacute spongioid encephalopathies (Creutzfeldt-Jakob syndrome and amyotrophic leukospongiosis)]
OT Prizhiznennaia laboratornaia diagnostika podostrykh spongioznykh entsefalopatiicheloveka (bolezni Kreittsfel'da-Jakoba i amiotroficheskogo leikospongioza)
QU Zhurnal Nevropatologii i Psikhiatrii Imeni S. S. Korsakova 1991; 91(2): 9-13
PT journal article
AB Methods aimed at the detection of causative agents in the CSF and peripheral blood lymphocytes are recommended for the use in intravital laboratory diagnosis of slow infections of the central nervous system. The results obtained enable recommending the biotest on guinea-pigs or indication of the causative agent of amyotrophic leukospongiosis (AL) in cell culture coupled with the punctate immunoenzyme assay for the diagnosis of AL. As to the diagnosis of Creutzfeldt-Jakob disease, it is suggested that the biotest on guinea-pigs and the punctate immunoenzyme assay may be used.
MH Adult; Aged; Animal; Antibodies, Viral/analysis; Brain Diseases/cerebrospinal fluid/*diagnosis/microbiology; Cerebrospinal Fluid/microbiology; Creutzfeldt-Jakob Syndrome/cerebrospinal fluid/*diagnosis/microbiology; Disease Models, Animal; English Abstract; Guinea Pigs; Human; Lymphocytes/microbiology; Middle Age; Slow Virus Diseases/cerebrospinal fluid/*diagnosis/microbiology; Viruses, Unclassified/immunology/isolation & purification
SP russisch
PO Russland