NR AGNT
AU Kitamoto,T.; Yi,R.; Mohri,S.; Tateishi,J.
TI Cerebral amyloid in mice with Creutzfeldt-Jakob disease is influenced by the strain of the infectious agent
QU Brain Research 1990 Jan 29; 508(1): 165-7
PT journal article
AB We examined Fukuoka-1 and Fukuoka-2 mouse-adapted Creutzfeldt-Jakob disease strains. Mice infected with the Fukuoka-2 strain have a higher incidence of kuru plaques, a higher concentration of proteinase-resistant prion protein, and a higher infectivity titer than do mice with the Fukuoka-1 strain. Thus, it must be kept in mind that there is a difference in the strain of the infectious agent in murine Creutzfeldt-Jakob disease.
MH Amyloidosis/*microbiology/pathology; Animal; Brain Diseases/*microbiology/pathology; Creutzfeldt-Jakob Syndrome/*microbiology/pathology; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Support, Non-U.S. Gov't
AD Department of Neuropathology, Kyushu University, Fukuoka, Japan.
SP englisch
PO Niederlande