NR AGEY

AU Kascsak,R.J.; Fersko,R.; Pulgiano,D.; Rubenstein,R.; Carp,R.I.

TI Immunodiagnosis of prion disease

QU Immunological Investigations 1997 Jan-Feb; 26(1-2): 259-68

PT journal article

AB The immunodiagnosis of prion diseases is of critical importance due to the transmissibility of these conditions and their fatal prognosis. A panel of monoclonal and polyclonal antibodies have been generated for use in the study and diagnosis of these diseases. This manuscript describes the generation and characterization of these antibodies as well as their diagnostic application.

ZR 21

MH Adult; Animal; Antibodies, Monoclonal/biosynthesis/diagnostic use; Antibodies, Viral/biosynthesis/diagnostic use; Hamsters; Human; Immunoassay/methods; Mesocricetus; Mice; Mice, Inbred BALB C; Mice, Knockout; Prion Diseases/*diagnosis/*immunology; Prions/*immunology; Rabbits; Support, Non-U.S. Gov't; Support, U.S. Gov't, P.H.S.

AD NYS Institute for Basic Research In Developmental Disabilities, Staten Island, New York 10314, USA

SP englisch

PO USA

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