NR AGDZ
AU Kan,R.; Takahashi,Y.; Sato,K.; Watabe,M.; Tago,H.; Yashima,Y.; Kumashiro,H.
TI Serial changes of SPECT in periodic synchronous discharges in a case with Creutzfeldt-Jakob disease
QU Japanese Journal of Psychiatry and Neurology 1992 Mar; 46(1): 175-9
PT journal article
AB We conducted serial EEG and SPECT studies on one female with Creutzfeldt-Jakob disease (CJD). In an analysis of EEG, a periodic synchronous discharge (PSD) was observed in the middle of the third stage (terminal stage) of Bernoulli's classification. The frequency of PSD was the highest at the beginning of the third stage, followed by a gradual decrease and disappeared at the end of the third stage. In the middle of the third stage, SPECT disclosed blood flow differences between the cerebrum and other regions (the cerebellum and the brainstem), while no such difference was observed by SPECT at the end of the third stage. It was suggested that the appearance of PSD requires the presence of a pathological change in the cerebrum precedent to other regions.
MH Aged; Brain/*blood supply/pathology; Brain Mapping; Case Report; Creutzfeldt-Jakob Syndrome/pathology/*radionuclide imaging; Electroencephalography; Female; Human; Neurologic Examination; Regional Blood Flow/physiology; *Tomography, Emission-Computed, Single-Photon
AD Department of Neuropsychiatry, Fukushima Medical College, Japan.
SP englisch
PO Japan