NR AEWJ
AU Greicius,M.D.; Geschwind,M.D.; Miller,B.L.
TI Presenile dementia syndromes: an update on taxonomy and diagnosis.
QU Journal of Neurology, Neurosurgery and Psychiatry 2002 Jun; 72(6): 691-700
PT journal article; review; review, tutorial
AB The four major degenerative dementias that often begin in presenescence: are reviewed. These are Alzheimer's disease, frontotemporal dementia, dementia with Lewy bodies, and Creutzfeldt-Jakob disease. Their epidemiological, genetic, and clinical features are reviewed, and controversies in taxonomy arising from recent discoveries described. Particular attention is given to the pathological role of protein aggregation, which appears to be a factor in each disease.
ZR 171
MH Aged; Alzheimer Disease/*diagnosis/epidemiology/genetics/*pathology; Diagnosis, Differential; *Genetic Predisposition to Disease; Human; Incidence; Support, Non-U.S. Gov't; Support, U.S. Gov't, P.H.S.
AD Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA
SP englisch
PO England