NR ADJO
AU Dickson,D.W.
TI Neuropathology of Alzheimer's disease and other dementias
QU Clinics in Geriatric Medicine 2001 May; 17(2): 209-28
PT journal article; review; review, tutorial
AB Clinical differentiation of neurodegenerative diseases that produce dementia is imprecise. Neuropathology offers the only way to make a definite diagnosis. The CNS autopsy is also important for clinical quality control and for providing tissue that furthers research into these disabling disorders. This brief article summarizes the major neuropathologic features of largely sporadic disorders that present with late-life dementia. The common causes of dementia discussed are Alzheimer's disease, Lewy body disease, and vascular dementia; less common disorders described are dementia lacking distinctive histopathology, Pick's disease, progressive supranuclear palsy, corticobasal degeneration, and Creutzfeldt-Jakob disease.
ZR 59
MH Alzheimer Disease/etiology/*pathology; Autopsy; Creutzfeldt-Jakob Syndrome/pathology; Dementia/classification/etiology/*pathology; Diagnosis, Differential; Human; Lewy Body Disease/pathology; Pick Disease of the Brain/pathology; Reproducibility of Results; Sensitivity and Specificity; Spinocerebellar Degenerations/pathology; Support, Non-U.S. Gov't; Support, U.S. Gov't, P.H.S.; Supranuclear Palsy, Progressive/pathology
AD Department of Pathology (Neuropathology), Mayo Clinic, Jacksonville, Florida, USA
SP englisch
PO USA