NR ADHG

AU Deslys,J.P.

TI [Risk prevention of transmissible subacute spongiform encephalopathies]

OT Prevention du risque d'encephalopathie spongiforme subaigue transmissible

QU Revue du Praticien 1999 May 1; 49(9): 966-70

PT journal article

AB The risk assessment of transmissible spongiform encephalopathies (TSEs or prion diseases) can be managed at three levels: 1. control of source material that could be potentially infected (biological products of human or animal origin, instruments in contact with these products); 2. control of the processes for the purification of biological products and instrument decontamination techniques; 3. evaluation of invasive medical or surgical acts. Highest infectivity is found in central nervous system. TSE agents do resist to almost all usual decontamination procedures. National recommended procedures include sodium hypochlorite 18,500 ppm or sodium hydroxide 1N for 1 hour and autoclaving at at least 134 degrees C for at least 18 min.

MH Caustics/pharmacology; Creutzfeldt-Jakob Syndrome/*prevention & control/*transmission; Decontamination/*methods; English Abstract; Guidelines; Human; Infection Control/*methods; Risk Assessment; Sodium Hydroxide/pharmacology; Surgical Equipment/*microbiology

AD Commissariat a l'energie atomique DSV/DRM Service de neurovirologie 92265 Fontenay-aux-Roses.

SP französisch

PO Frankreich

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