NR ADCG
AU de Priester,J.A.; Jansen,G.H.; de Kruijk,J.R.; Wilmink,J.T.
TI New MRI findings in Creutzfeldt-Jakob disease: high signal in the globus pallidus on T1-weighted images.
QU Neuroradiology 1999 Apr; 41(4): 265-8
PT journal article
AB We report a 49-year-old woman with Creutzfeldt-Jakob disease (CJD). In addition to typical high-signal lesions on proton-density and T2-weighted images there was high signal in the globus pallidus bilaterally on T1-weighted images. The latter feature has not been described previously and probably due to deposition of prion protein, as found at autopsy.
IN Bei einer 49 Jahre alten Creutzfeldt-Jakob-Patientin wurde eine Magnetfeldresonanzaufnahme gemacht. Außer den typischen Veränderungen auf Protonendichtebildern und T2-gewichteten Darstellungen, fand man auf T1-gewichteten Darstellungen starke Signale beidseitig im Globus pallidus. Die Autoren vermuten Prionproteinablagerungen als Ursache.
ZR 11
MH Case Report; Caudate Nucleus/pathology; Contrast Media; Creutzfeldt-Jakob Syndrome/diagnosis/*pathology; Fatal Outcome; Female; Gadolinium DTPA/diagnostic use; Globus Pallidus/*pathology; Gyrus Cinguli/pathology; Human; Image Processing, Computer-Assisted/methods; Immunohistochemistry; Magnetic Resonance Imaging/*methods; Middle Age; Prions/analysis; Putamen/pathology
AD Department of Radiology, University Hospital Maastricht, The Netherlands.
SP englisch
PO Deutschland