NR ACHO
AU Caselli,R.J.; Couce,M.E.; Osborne,D.; Deen,H.G.; Parisi,J.P.
TI From slowly progressive amnesic syndrome to rapidly progressive Alzheimer disease
QU Alzheimer Disease and Associated Disorders 1998 Sep; 12(3): 251-3
PT journal article
AB A 57-year-old woman had a neuropsychologically documented 5-year history of a slowly progressive amnesic syndrome followed by a 1-year history of rapidly progressive dementia. There was no family history of dementia. Magnetic resonance imaging failed to show a structural basis, electroencephalography failed to show changes of Creutzfeldt-Jakob disease, and cerebrospinal fluid examination was normal. A diagnosis of Alzheimer disease was confirmed by brain biopsy. The abrupt change in disease course was unique but suggested probable overlap between posited subtypes of Alzheimer disease.
MH Alzheimer Disease/*diagnosis/psychology; Amnesia/*diagnosis/psychology; Brain/pathology; Case Report; Diagnosis, Differential; Female; Follow-Up Studies; Human; Magnetic Resonance Imaging; Middle Age; Neuropsychological Tests; Support, Non-U.S. Gov't; Syndrome
AD Department of Neurology, Mayo Clinic, Scottsdale, Arizona 85259, USA
SP englisch
PO USA