NR ACEF
AU Cambier,J.
TI [The biology of prions, a response to the enigma of spongiform encephalopathies of sheep and humans]
OT La biologie des prions, une reponse a l'enigme des encephalopathies spongiformes des moutons et des hommes
QU Bulletin de l'Académie Nationale de Médecine 1990 Dec; 174(9): 1353-7; discussion 1357-9
PT journal article; review; review, tutorial
AB Prions are small proteinaceous infectious particles without nucleic acids. The prion protein arise from a cellular protein by a post-transduction event and constitute amyloid deposits. Prions are the agent of animal and human spongiform encephalopathies which evolve on simultaneous infectious and genetic dependence in the absence of a detectable immune response.
ZR 11
MH Animal; Biology; Creutzfeldt-Jakob Syndrome/*microbiology; English Abstract; Human; Prions/*physiology; Scrapie/*microbiology; Sheep
AD Clinique neurologique, Hopital Beaujon, Clichy.
SP französisch
PO Frankreich