NR ABYD

AU Brugere-Picoux,J.; Rerat,A.

TI [Bovine spongiform encephalopathy. Review of data collected since the statement of February 6, 1996]

OT Encephalopathie spongiforme bovine. Mise au point des donnees recueillies depuis le voeu du 6 fevrier 1996.

QU Bulletin de l'Académie Nationale de Médecine 1996 May; 180(5): 1007-12; discussion 1012-5

PT journal article; review; review, tutorial

AB The observation in 1995 and 1996 of 10 cases of a new variant of Creutzfeldt-Jakob disease (V-CJD) in U.K. suggested a possible relation between this human cases and bovine spongiform encephalopathy (BSE). Recent papers about this topic are reviewed : hypothesis of a possible genetic link between man and cattle, hypothesis of a acquired resistance against the agent of BSE after a previous infection by a less virulent agent of ovine origin, importance of polymorphism at codon 129 according to the hypothesis of a virus-induced amyloidosis, diagnostic test with cerebrospinal fluid, epidemiology of BSE and prediction of future BSE spread.

ZR 11

MH Animal; Cattle; Creutzfeldt-Jakob Syndrome/epidemiology/*genetics/virology; Encephalopathy, Bovine Spongiform/epidemiology/*genetics/virology; English Abstract; Human; Incidence; Polymorphism (Genetics)

AD Pathologie medicale du betail et des animaux de basse-cour, Ecole nationale veterinaire d'Alfort, Maisons-Alfort, France.

SP französisch

PO Frankreich

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