NR ABUX
AU Brown,P.
TI The "brave new world" of transmissible spongiform encephalopathy (infectious cerebral amyloidosis)
QU Molecular Neurobiology 1994 Apr-Jun; 8(2-3): 79-87
PT historical article; journal article; review; review, tutorial
AB The story of transmissible human spongiform encephalopathy, from its origins to the present time, enjoys the commentary of a cast of characters from Shakespeare's imaginary island in The Tempest, with a brief visit to the real island of Tasmania for a bird's eye view of the prion, and some concluding thoughts about the current state of research in the netherworlds of molecular biology and physical chemistry.
ZR 81
MH Animal; Birds; History of Medicine, Modern; Human; Prion Diseases/history/*physiopathology; Prions/chemistry; Protein Structure, Secondary; Tasmania
AD Paul Brown (pwb@codon.nih.gov), Laboratory of Central Nervous System Studies, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
SP englisch
PO USA