NR AAHH

AU Andrews,N.J.; Farrington,C.P.; Cousens,S.N.; Smith,P.G.; Ward,H.J.T.; Knight,R.S.G.; Ironside,J.W.; Will,R.G.

TI Incidence of variant Creutzfeldt-Jakob disease in the UK

QU Lancet 2000 Aug 5; 356(9228): 481-2

PT letter

AB The number of deaths from variant CJD (vCJD) in the UK increased in the last quarter of 1998, although numbers were lower in subsequent quarters. We analysed the numbers of definite and probable (living and dead) vCJD cases since 1994 to assess trends in incidence. We estimated that the number of onsets increased by 23% per year for 1994-2000 (p=0.004), and that deaths increased by 33% for 1995-2000 (p=0.005). The absolute number of cases in the UK is still low, but such an increase should be a matter of concern.

MH Creutzfeldt-Jakob Syndrome/*epidemiology; Great Britain/epidemiology; Human; Incidence

AD N. J. Andrews, A. M. Molesworth, Public Health Laboratory Service, Communicable Disease Surveillance Centre, London, UK; C. P. Farrington, Department of Statistics, Open University, Milton Keynes; P. G. Smith, S. N. Cousens (s.cousens@lshtm.ac.uk), Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK; H. J. T. Ward, R. S. G. Knight, J. W. Ironside, R. G. Will, National CJD Surveillance Unit, Western General Hospital, Edinburgh, UK

SP englisch

PO England

EA pdf-Datei

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