NR AAEM
AU Aksamit,A.J.Jr.; Preissner,C.M.; Homburger,H.A.
TI Quantitation of 14-3-3 and neuron-specific enolase proteins in CSF in Creutzfeldt-Jakob disease
QU Neurology 2001 Aug 28; 57(4): 728-30
PT journal article
AB CSF 14-3-3 and neuron-specific enolase (NSE) proteins were quantitated from patients who had Creutzfeldt-Jakob disease (CJD) or other rapidly dementing disorders initially considered to be CJD. Thirty-one patients were diagnosed as having CJD among 152 studied. CSF 14-3-3 values more than 8 ng/mL correlated with CJD. CSF NSE values less than 30 ng/mL and 14-3-3 values less than 8 ng/mL made a diagnosis of CJD unlikely, but did not exclude it.
MH Creutzfeldt-Jakob Syndrome/*cerebrospinal fluid/diagnosis/enzymology; Human; Phosphopyruvate Hydratase/*cerebrospinal fluid; Retrospective Studies; Tyrosine 3-Monooxygenase/*cerebrospinal fluid
AD Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
SP englisch
PO USA