NR ZCWY

AU Broomhead,C.J.; Wright,S.J.; Kiff,K.M.; Withington,P.S.

TI Thoracic electrical bioimpedance: a non-invasive measure of cardiac output for porcine research

QU Laboratory animals 1982; 32: 324-329

PT journal article

AB A comparison of two techniques for measuring cardiac output, thermodilution (TD) and thoracic electrical bioimpedance (TEB) was undertaken in a porcine model. Eight anaesthetized large white pigs were studied. A total of 436 paired measurements were performed over a range of cardiac outputs from 1.7 to 15.1 l/min as measured by thermodilution. The Pearson product moment correlation coefficient was r=0.963 with p<0.001. Analysis by Bland and Altman statistics revealed a mean difference (bias) of -0.02 l/min and the limits of agreement were + 1.6 l/min, similar to figures found in human comparative studies. These results confirm that thoracic electrical bioimpedance is a valid method of measuring cardiac output in pigs. It has significant advantages compared to thermodilution, in particular it is cheap, simple to use, noninvasive and provides continuous data.

AD The Sir Henry Souttar Research Laboratories, The Royal Hospitals Trust, The Royal London Hospital, London, UK

SP englisch

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