NR ZCWV
AU Brechner,V.L.; Bauer,R.O.; Bethune,R.W.M.; Phillips,R.E.; Kavan,E.M.; Dillon,J.B.
TI Electroencephalographic effect of arrested circulation in the normothermic human and dog
QU Anesthesia and Analgesia 1961; 40: 1-14
PT journal article
AB Electroencephalographic response of dogs to circulatory standstill is presented. It is found that duration of a single circulatory arrest is correlated with duration of time lapse until onset of continuous electrical activity following restoration of circulation as a straight line when plotted logarithmically. A similar regression line has been described previously for the hypthermic human. The difference of the slope of these two lines indicates that the human electroencephalographic response, even during hypthermia, is more susceptible to ischemic trauma than the normothermic dog. The records of 6 normothermic humans experiencing unexpected circulatory arrest are reviewed and prognostic criteria presented. A good prognosis is indicated b a return of continuous electrocortical activity within 15 minutes and a rapid progression of the activity to light levels of cerebral depression (fast frequency, low voltage) within 25 minutes of cardiorespiratory resuscitation. Poor prognosis was indicated by a delay of more than 15 minutes in return of continuous eletrocortical activity and little or no tendency for pattern, once established, to rapidly progress to levels of light cerebral depression.
AD Division of Anesthesia; Department of Surgery, University of California Medical Center, Los Angeles, California, USA
SP englisch
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