NR ZBDB

AU Smith,W.; Harrap,S.B.

TI Behavioural and cardiovascular responses of rats to euthanasia using carbon dioxide gas

QU Laboratory Animals 1997 Oct; 31(4): 337-46

PT journal article

AB Our results showed more rapid falls in pulse rate and blood pressure in rats euthanized in a chamber precharged with carbon dioxide (CO2), when compared with rats euthanized more slowly, but death still took over 5 min in the former group. There was no behavioural evidence of pain or distress in either group during euthanasia. Initial ataxia and dyspnoea was punctuated by a lag before death, thus separating euthanasia into three clearly defined phases. All visual signs of death preceded complete vascular collapse by about 1 min in both groups, so we recommend that gas flow be maintained for at least 1 min after apparent death.

AD Department of Science and Technology, Western Melbourne Institute of Technical and Further Education, Footscray, Victoria, Australia.

SP englisch

PO England

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